Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Orit Harari-Steinberg"'
Autor:
Dorit Omer, Osnat Cohen Zontag, Yehudit Gnatek, Orit Harari-Steinberg, Oren Pleniceanu, Michael Namestnikov, Ayelet-Hashahar Cohen, Malka Nissim-Rafinia, Gal Tam, Tomer Kalisky, Eran Meshorer, Benjamin Dekel
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 329-346 (2023)
Upscaling of kidney epithelial cells is crucial for renal regenerative medicine. Nonetheless, the adult kidney lacks a distinct stem cell hierarchy, limiting the ability to long-term propagate clonal populations of primary cells that retain renal ide
Externí odkaz:
https://doaj.org/article/2816b5ae0eef4665ac0e00b61574ad07
Autor:
Orit Harari-Steinberg, Dorit Omer, Yehudit Gnatek, Oren Pleniceanu, Sanja Goldberg, Osnat Cohen-Zontag, Sara Pri-Chen, Itamar Kanter, Nissim Ben Haim, Eli Becker, Roi Ankawa, Yaron Fuchs, Tomer Kalisky, Zohar Dotan, Benjamin Dekel
Publikováno v:
Cell Reports, Vol 30, Iss 3, Pp 852-869.e4 (2020)
Summary: End-stage renal disease is a worldwide epidemic requiring renal replacement therapy. Harvesting tissue from failing kidneys and autotransplantation of tissue progenitors could theoretically delay the need for dialysis. Here we use healthy an
Externí odkaz:
https://doaj.org/article/9d98aec17bda4af89b45646d801e3a42
Autor:
Hana Golan, Rachel Shukrun, Revital Caspi, Einav Vax, Naomi Pode-Shakked, Sanja Goldberg, Oren Pleniceanu, Dekel D. Bar-Lev, Michal Mark-Danieli, Sara Pri-Chen, Jasmine Jacob-Hirsch, Itamar Kanter, Ariel Trink, Ginette Schiby, Ron Bilik, Tomer Kalisky, Orit Harari-Steinberg, Amos Toren, Benjamin Dekel
Publikováno v:
Stem Cell Reports, Vol 11, Iss 3, Pp 795-810 (2018)
Summary: Cancer stem cell (CSC) identification relies on transplantation assays of cell subpopulations sorted from fresh tumor samples. Here, we attempt to bypass limitations of abundant tumor source and predetermined immune selection by in vivo prop
Externí odkaz:
https://doaj.org/article/c8975f3987c644cb807934810287d3c9
Publikováno v:
Kidney International Reports, Vol 3, Iss 1, Pp 155-159 (2018)
Renal angiomyolipoma (AML) is the most common benign renal tumor. Despite a generally benign histology, AML can result in significant morbidity, from intra-abdominal hemorrhage and reduction in kidney function. While classically associated with the a
Externí odkaz:
https://doaj.org/article/b72d2bbf51cb4b6ba37c2077b1db75d7
Autor:
Naomi Pode-Shakked, Rotem Gershon, Gal Tam, Dorit Omer, Yehudit Gnatek, Itamar Kanter, Sarit Oriel, Guy Katz, Orit Harari-Steinberg, Tomer Kalisky, Benjamin Dekel
Publikováno v:
Stem Cell Reports, Vol 9, Iss 1, Pp 279-291 (2017)
During nephrogenesis, stem/progenitor cells differentiate and give rise to early nephron structures that segment to proximal and distal nephron cell types. Previously, we prospectively isolated progenitors from human fetal kidney (hFK) utilizing a co
Externí odkaz:
https://doaj.org/article/d8cb8a41442a4e62802a6d3cc08bb555
Autor:
Oren Pleniceanu, Racheli Shukrun, Dorit Omer, Einav Vax, Itamar Kanter, Klaudyna Dziedzic, Naomi Pode‐Shakked, Michal Mark‐Daniei, Sara Pri‐Chen, Yehudit Gnatek, Hadas Alfandary, Nira Varda‐Bloom, Dekel D Bar‐Lev, Naomi Bollag, Rachel Shtainfeld, Leah Armon, Achia Urbach, Tomer Kalisky, Arnon Nagler, Orit Harari‐Steinberg, Jack L Arbiser, Benjamin Dekel
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 4, Pp 508-530 (2017)
Abstract Angiomyolipoma (AML), the most common benign renal tumor, can result in severe morbidity from hemorrhage and renal failure. While mTORC1 activation is involved in its growth, mTORC1 inhibitors fail to eradicate AML, highlighting the need for
Externí odkaz:
https://doaj.org/article/04ce0232c4284454b179f5026fd0dc37
Autor:
Osnat Cohen-Zontag, Rotem Gershon, Orit Harari-Steinberg, Itamar Kanter, Dorit Omer, Oren Pleniceanu, Gal Tam, Sarit Oriel, Herzl Ben-Hur, Guy Katz, Zohar Dotan, Tomer Kalisky, Benjamin Dekel, Naomi Pode-Shakked
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/bce24d4e18a347fea8d96080238465b7
Autor:
Rachel Shukrun, Naomi Pode-Shakked, Oren Pleniceanu, Dorit Omer, Einav Vax, Eyal Peer, Sara Pri-Chen, Jasmine Jacob, Qianghua Hu, Orit Harari-Steinberg, Vicki Huff, Benjamin Dekel
Publikováno v:
Stem Cell Reports, Vol 3, Iss 1, Pp 24-33 (2014)
An open question remains in cancer stem cell (CSC) biology whether CSCs are by definition at the top of the differentiation hierarchy of the tumor. Wilms’ tumor (WT), composed of blastema and differentiated renal elements resembling the nephrogenic
Externí odkaz:
https://doaj.org/article/b7664ab913154a2d8af8c12f9ddde693
Autor:
Yuval Rinkevich, Daniel T. Montoro, Humberto Contreras-Trujillo, Orit Harari-Steinberg, Aaron M. Newman, Jonathan M. Tsai, Xinhong Lim, Renee Van-Amerongen, Angela Bowman, Michael Januszyk, Oren Pleniceanu, Roel Nusse, Michael T. Longaker, Irving L. Weissman, Benjamin Dekel
Publikováno v:
Cell Reports, Vol 7, Iss 4, Pp 1270-1283 (2014)
The mechanism and magnitude by which the mammalian kidney generates and maintains its proximal tubules, distal tubules, and collecting ducts remain controversial. Here, we use long-term in vivo genetic lineage tracing and clonal analysis of individua
Externí odkaz:
https://doaj.org/article/5859db2fcb9a4aee8444a48bed517787
Autor:
Orit Harari‐Steinberg, Sally Metsuyanim, Dorit Omer, Yehudit Gnatek, Rotem Gershon, Sara Pri‐Chen, Derya D. Ozdemir, Yaniv Lerenthal, Tzahi Noiman, Herzel Ben‐Hur, Zvi Vaknin, David F. Schneider, Bruce J. Aronow, Ronald S. Goldstein, Peter Hohenstein, Benjamin Dekel
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 10, Pp 1556-1568 (2013)
Abstract Identification of tissue‐specific renal stem/progenitor cells with nephrogenic potential is a critical step in developing cell‐based therapies for renal disease. In the human kidney, stem/progenitor cells are induced into the nephrogenic
Externí odkaz:
https://doaj.org/article/b0a80b1c58cc4d72bc2064b920df87ed