Relevance of tissue-resident memory CD8 T cells in the onset of Parkinson’s disease and examination of its possible etiologies: infectious or autoimmune?

Autor: Oriol de Fàbregues, Maria Sellés, David Ramos-Vicente, Gerard Roch, Miquel Vila, Jordi Bové

Publikováno v: Neurobiology of Disease, Vol 187, Iss , Pp 106308- (2023)

Tissue-resident memory CD8 T cells are responsible for local immune surveillance in different tissues, including the brain. They constitute the first line of defense against pathogens and cancer cells and play a role in autoimmunity. A recently publi

Externí odkaz: https://doaj.org/article/d2e156eb33404de8ba4e16826f5c3081

The Onset of Nonmotor Symptoms in Parkinson's Disease (The ONSET PD Study)

Autor: Claustre, Pont-Sunyer, Anna, Hotter, Carles, Gaig, Klaus, Seppi, Yaroslau, Compta, Regina, Katzenschlager, Natalia, Mas, Dominik, Hofeneder, Thomas, Brücke, Angels, Bayés, Karoline, Wenzel, Jon, Infante, Heidemarie, Zach, Walter, Pirker, Ignacio J, Posada, Ramiro, Álvarez, Lourdes, Ispierto, Oriol, De Fàbregues, Antoni, Callén, Antoni, Palasí, Miquel, Aguilar, Maria José, Martí, Francesc, Valldeoriola, Manel, Salamero, Werner, Poewe, Eduardo, Tolosa

Publikováno v: MOVEMENT DISORDERS
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

Nonmotor symptoms (NMS) in Parkinson's disease (PD) can precede onset of motor symptoms. Relationship between premotor symptoms onset and motor features is limited. Our aim is to describe the presence and perceived onset of NMS in PD as well as their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f23db9b0486f5952f7dca54971ed86b1
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=9417

Identifying comorbidities and lifestyle factors contributing to the cognitive profile of early Parkinson’s disease

Autor: Saul Martínez-Horta, Helena Bejr-Kasem, Andrea Horta-Barba, Berta Pascual-Sedano, Diego Santos-García, Teresa de Deus-Fonticoba, Silvia Jesús, Miquel Aguilar, Lluis Planellas, Juan García-Caldentey, Nuria Caballol, Bárbara Vives-Pastor, Jorge Hernández-Vara, Iria Cabo-Lopez, Lydia López-Manzanares, Isabel González-Aramburu, Maria Asunción Ávila-Rivera, Maria Jose Catalán, Luis Manuel López-Díaz, Victor Puente, Jose Manuel García-Moreno, Carmen Borrué, Berta Solano-Vila, Maria Álvarez-Sauco, Lydia Vela, Sonia Escalante, Esther Cubo, Francisco Carrillo-Padilla, Juan Carlos Martínez-Castrillo, Pilar Sánchez-Alonso, Maria Gema Alonso-Losada, Nuria López-Ariztegui, Itziar Gastón, Marta Blázquez-Estrada, Manual Seijo-Martínez, Javier Rúiz-Martínez, Caridad Valero-Merino, Monica Kurtis, Oriol de Fábregues-Boixar, Jessica González-Ardura, Cristina Prieto-Jurczynska, Pablo Martinez-Martin, Pablo Mir, Jaime Kulisevsky, COPPADIS Study Group

Publikováno v: BMC Neurology, Vol 21, Iss 1, Pp 1-10 (2021)

Abstract Background Identifying modifiable risk factors for cognitive impairment in the early stages of Parkinson’s disease (PD) and estimating their impact on cognitive status may help prevent dementia (PDD) and the design of cognitive trials. Met

Externí odkaz: https://doaj.org/article/0b9e0017c31e42568071f0f6b4ae9a90

Motor Fluctuations Development Is Associated with Non-Motor Symptoms Burden Progression in Parkinson’s Disease Patients: A 2-Year Follow-Up Study

Autor: Diego Santos-García, Teresa de Deus Fonticoba, Carlos Cores Bartolomé, Maria J. Feal Painceiras, Ester Suárez Castro, Héctor Canfield, Cristina Martínez Miró, Silvia Jesús, Miquel Aguilar, Pau Pastor, Lluís Planellas, Marina Cosgaya, Juan García Caldentey, Nuria Caballol, Ines Legarda, Jorge Hernández-Vara, Iria Cabo, Lydia López Manzanares, Isabel González Aramburu, Maria A. Ávila Rivera, Víctor Gómez Mayordomo, Víctor Nogueira, Víctor Puente, Julio Dotor García-Soto, Carmen Borrué, Berta Solano Vila, María Álvarez Sauco, Lydia Vela, Sonia Escalante, Esther Cubo, Francisco Carrillo Padilla, Juan C. Martínez Castrillo, Pilar Sánchez Alonso, Maria G. Alonso Losada, Nuria López Ariztegui, Itziar Gastón, Jaime Kulisevsky, Marta Blázquez Estrada, Manuel Seijo, Javier Rúiz Martínez, Caridad Valero, Mónica Kurtis, Oriol de Fábregues, Jessica González Ardura, Ruben Alonso Redondo, Carlos Ordás, Luis M. López Díaz, Darrian McAfee, Pablo Martinez-Martin, Pablo Mir, COPPADIS Study Group

Publikováno v: Diagnostics, Vol 12, Iss 5, p 1147 (2022)

Objective: The aim of the present study was to analyze the progression of non-motor symptoms (NMS) burden in Parkinson’s disease (PD) patients regarding the development of motor fluctuations (MF). Methods: PD patients without MF at baseline, who we

Externí odkaz: https://doaj.org/article/1218cb6a14ba4fd18f2a0c554798e52f

Diplopia Is Frequent and Associated with Motor and Non-Motor Severity in Parkinson’s Disease: Results from the COPPADIS Cohort at 2-Year Follow-Up

Autor: Diego Santos García, Lucía Naya Ríos, Teresa de Deus Fonticoba, Carlos Cores Bartolomé, Lucía García Roca, Maria Feal Painceiras, Cristina Martínez Miró, Hector Canfield, Silvia Jesús, Miquel Aguilar, Pau Pastor, Marina Cosgaya, Juan García Caldentey, Nuria Caballol, Inés Legarda, Jorge Hernández Vara, Iria Cabo, Lydia López Manzanares, Isabel González Aramburu, María A. Ávila Rivera, Víctor Gómez Mayordomo, Víctor Nogueira, Víctor Puente, Julio Dotor, Carmen Borrué, Berta Solano Vila, María Álvarez Sauco, Lydia Vela, Sonia Escalante, Esther Cubo, Francisco Carrillo Padilla, Juan C. Martínez Castrillo, Pilar Sánchez Alonso, Maria G. Alonso Losada, Nuria López Ariztegui, Itziar Gastón, Jaime Kulisevsky, Marta Blázquez Estrada, Manuel Seijo, Javier Rúiz Martínez, Caridad Valero, Mónica Kurtis, Oriol de Fábregues, Jessica González Ardura, Ruben Alonso Redondo, Carlos Ordás, Luis M. López Díaz, Darrian McAfee, Pablo Martinez-Martin, Pablo Mir

Publikováno v: Diagnostics, Vol 11, Iss 12, p 2380 (2021)

Background and objective: Diplopia is relatively common in Parkinson’s disease (PD) but is still understudied. Our aim was to analyze the frequency of diplopia in PD patients from a multicenter Spanish cohort, to compare the frequency with a contro

Externí odkaz: https://doaj.org/article/ef37b897ddbc45bc869ba2deee31cd15