Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Oriol Sunyer"'
Autor:
Ariel Shepley-McTaggart, Jingjing Liang, Yang Ding, Marija A Djurkovic, Valeriia Kriachun, Olena Shtanko, Oriol Sunyer, Ronald N Harty
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011595 (2023)
Ebola (EBOV) and Marburg viruses (MARV) cause severe hemorrhagic fever associated with high mortality rates in humans. A better understanding of filovirus-host interactions that regulate the EBOV and MARV lifecycles can provide biological and mechani
Externí odkaz:
https://doaj.org/article/fbe473186be64d29a4b95c1fd33611c7
Autor:
Susana Magadan, Aleksei Krasnov, Saida Hadi-Saljoqi, Sergey Afanasyev, Stanislas Mondot, Delphine Lallias, Rosario Castro, Irene Salinas, Oriol Sunyer, John Hansen, Ben F. Koop, Marie-Paule Lefranc, Pierre Boudinot
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
In teleost fish as in mammals, humoral adaptive immunity is based on B lymphocytes expressing highly diverse immunoglobulins (IG). During B cell differentiation, IG loci are subjected to genomic rearrangements of V, D, and J genes, producing a unique
Externí odkaz:
https://doaj.org/article/6d0ab8ee5edf4b4b96373c27329bfcc8
Autor:
Susana Magadan, Luc Jouneau, Maximilian Puelma Touzel, Simon Marillet, Wahiba Chara, Adrien Six, Edwige Quillet, Thierry Mora, Aleksandra M. Walczak, Frédéric Cazals, Oriol Sunyer, Simon Fillatreau, Pierre Boudinot
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Vaccination induces “public” antibody clonotypes common to all individuals of a species, that may mediate universal protection against pathogens. Only few studies tried to trace back the origin of these public B-cell clones. Here we used Illumina
Externí odkaz:
https://doaj.org/article/ecf3be8b01c347e9bd318d5dedbe6dc7
Autor:
Rosario Castro, Luc Jouneau, Hang-Phuong Pham, Olivier Bouchez, Véronique Giudicelli, Marie-Paule Lefranc, Edwige Quillet, Abdenour Benmansour, Frédéric Cazals, Adrien Six, Simon Fillatreau, Oriol Sunyer, Pierre Boudinot
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003098 (2013)
Upon infection, B-lymphocytes expressing antibodies specific for the intruding pathogen develop clonal responses triggered by pathogen recognition via the B-cell receptor. The constant region of antibodies produced by such responding clones dictates
Externí odkaz:
https://doaj.org/article/7be38ef00475454db7f8e1a913d761bf
Autor:
Fumio Takizawa, Keiichiro Hashimoto, Ryuichiro Miyazawa, Yuko Ohta, Ana Veríssimo, Martin F. Flajnik, David Parra, Kotaro Tokunaga, Hiroaki Suetake, J. Oriol Sunyer, Johannes M. Dijkstra
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
CD4 and LAG-3 are related molecules that are receptors for MHC class II molecules. Their major functional differences are situated in their cytoplasmic tails, in which CD4 has an activation motif and LAG-3 an inhibitory motif. Here, we identify shark
Externí odkaz:
https://doaj.org/article/de4d4f3355de47cb9c19eab95512dd69
Autor:
Yongyao Yu, Zhenyu Huang, Weiguang Kong, Fen Dong, Xiaoting Zhang, Xue Zhai, Gaofeng Cheng, Mengting Zhan, Jiafeng Cao, Liguo Ding, Guangkun Han, Fumio Takizawa, Yang Ding, J. Oriol Sunyer, Zhen Xu
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-18 (2022)
Abstract The air-filled organs (AOs) of vertebrates (lungs and swim bladders) have evolved unique functions (air-breathing or buoyancy control in water) to adapt to different environments. Thus far, immune responses to microbes in AOs have been descr
Externí odkaz:
https://doaj.org/article/d9661bdf14964fa69426b6f3bb1ce769
Autor:
Yong-Yao Yu, Wei-Guang Kong, Hao-Yue Xu, Zhen-Yu Huang, Xiao-Ting Zhang, Li-Guo Ding, Shuai Dong, Guang-Mei Yin, Fen Dong, Wei Yu, Jia-Feng Cao, Kai-Feng Meng, Xia Liu, Yu Fu, Xue-zhen Zhang, Yong-an Zhang, J. Oriol Sunyer, Zhen Xu
Publikováno v:
iScience, Vol 19, Iss , Pp 821-835 (2019)
Summary: The buccal mucosa (BM) is a critical first line of defense in terrestrial animals. To gain further insights into the evolutionary origins and primordial roles of BM in teleosts here we show that rainbow trout, a teleost fish, contains a diff
Externí odkaz:
https://doaj.org/article/48c6bc436b3d40f785ec8de9eaf40210
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Understanding of immune function in humans and model organisms, such as mice, has advanced in the last few decades because of technological breakthroughs and availability of reagents. While novel genomic technologies have helped to increase knowledge
Externí odkaz:
https://doaj.org/article/f349d5a4bee34d1da45f6881f00c1682
Autor:
Yang Ding, Alvaro Fernández-Montero, Amir Mani, Elisa Casadei, Yasuhiro Shibasaki, Fumio Takizawa, Ryuichiro Miyazawa, Irene Salinas, J. Oriol Sunyer
Publikováno v:
bioRxiv
The co-evolution between secretory immunoglobulins (sIgs) and microbiota began with the emergence of IgM over half a billion years ago. Yet, IgM function in vertebrates is mostly associated with systemic immunity against pathogens. sIgA and sIgT are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fcaedb7fb34f163a81c0c7818000aef
https://doi.org/10.1101/2023.02.26.530119
https://doi.org/10.1101/2023.02.26.530119
Autor:
Meng-Ting Zhan, Jia-Feng Cao, Zheng-Ben Wu, Kai-Feng Meng, J. Oriol Sunyer, Zhenyu Huang, Li-Guo Ding, Xia Liu, Weiguang Kong, Yongyao Yu, Nan Li, Guang-Kun Han, Xiao-Ting Zhang, Fumio Takizawa, Zhen Xu, Hao-Yue Xu
Publikováno v:
The Journal of Immunology. 206:1088-1101
The skin of vertebrates is the outermost organ of the body and serves as the first line of defense against external aggressions. In contrast to mammalian skin, that of teleost fish lacks keratinization and has evolved to operate as a mucosal surface