Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Oriol Bassas"'
Publikováno v:
ARKIVOC, Vol 2003, Iss 10, Pp 69-81 (2003)
Externí odkaz:
https://doaj.org/article/b424d21d7cfc42b8bca0508a9f5f0a5e
Publikováno v:
European Journal of Organic Chemistry. 2009:1340-1351
This paper describes a new procedure for the enantioselective synthesis of the important anticonvulsant drug Pregabalin, which shows biological properties as the (S) enantiomer only. The key step of the synthetic sequence is the Michael addition reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452db65652fd6f5f73bc5004782a8b4d
https://doi.org/10.1002/ejoc.200801220
https://doi.org/10.1002/ejoc.200801220
Autor:
Oriol Bassas, Mark Edgar, Mercedes Amat, Liam J. Duffy, Joan Bosch, Philip C. Bulman Page, Michael J. McKenzie, Vickie McKee, Steven M. Allin, Maria M. M. Santos
Publikováno v:
Tetrahedron Letters. 47:5713-5716
We report new and complementary routes for the highly stereoselective construction of functionalized benzoquinolizidine targets from readily available, non-racemic chiral templates. The methods developed allow us to predetermine relative product ster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1236bc341aca2bc00b2367af2584ec25
https://doi.org/10.1016/j.tetlet.2006.06.035
https://doi.org/10.1016/j.tetlet.2006.06.035
Publikováno v:
Tetrahedron. 61:7693-7702
Several synthetic routes to 3-acetonyl- and 3-(2-oxoethyl)glutarates 1–5 have been explored. The most advantageous involves, as the key steps, the conjugate addition of an appropriately substituted vinylmagnesium bromide to an alkylidenemalonic est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d64935c72365ea55570e775359ff43bc
https://doi.org/10.1016/j.tet.2005.05.084
https://doi.org/10.1016/j.tet.2005.05.084
Autor:
Marta Huguet, Juan Aguilar, Mercedes Amat, Oriol Bassas, Laura Baldomà, Josefa Badia, Núria Llor, Antonia M. Gómez, Joan Bosch
Publikováno v:
Tetrahedron Letters. 45:5355-5358
Cyclocondensation of ( R )-phenylglycinol with appropriately γ-substituted δ -oxo acid derivatives provides bicyclic lactams from which the enantioselective synthesis of 1-deoxy- d -gulonojirimycin has been reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92b62fd65de98986a8719276128fbffb
https://doi.org/10.1016/j.tetlet.2004.05.089
https://doi.org/10.1016/j.tetlet.2004.05.089
Publikováno v:
ARKIVOC, Vol 2003, Iss 10, Pp 69-81 (2003)
The stereochemical outcome of cyclocondensation reactions of racemic and prochiral aldehyde and keto acid derivatives with (R)-phenylglycinol, leading to 7-substituted pyrrolidine-derived bicyclic lactams, is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c04ad1c99f9a419793f3c94896b417
https://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.0004.a09
https://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.0004.a09
Publikováno v:
Chem. Commun.. :1327-1329
Cyclocondensation reactions of aminoalcohols and with racemic or prochiral delta-oxoacid derivatives provide polysubstituted lactams with high enantioselectivity in a process that involves dynamic kinetic resolution and/or desymmetrization of enantio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d07b5c1d93bd7bab5f9d0c74c9e628a
https://doi.org/10.1039/b413937b
https://doi.org/10.1039/b413937b
Autor:
Carmen Escolano, Oriol Bassas, Joan Bosch, Maria M. M. Santos, Steven M. Allin, Núria Llor, Arantxa Gómez-Esqué, Mercedes Amat, Elies Molins, Vickie McKee
Publikováno v:
The Journal of organic chemistry. 72(14)
An enantioselective two-step route to substituted benzo[a]- and indolo[2,3-a]quinolizidines has been developed. It consists of (i) a stereoselective cyclocondensation of a racemic or prochiral delta-oxo(di)ester with either (S)-(3,4-dimethoxyphenyl)a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b7de54b18091df57ef9723794b9e98
https://pubmed.ncbi.nlm.nih.gov/17547461
https://pubmed.ncbi.nlm.nih.gov/17547461
Autor:
Oriol Bassas, Joan Bosch, Mercedes Amat, Margalida Cantó, Elies Molins, Núria Llor, Maria Pérez
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
A straightforward procedure for the synthesis of enantiopure polysubstituted piperidines is reported. It involves the direct generation of chiral non-racemic oxazolo[3,2-a]piperidone lactams that already incorporate carbon substituents on the heteroc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ec124d87b541e5d80fab87fd8dbb7b
http://hdl.handle.net/2445/162922
http://hdl.handle.net/2445/162922
Autor:
Rosa Griera, Oriol Bassas, Elies Molins, Joan Bosch, Maria M. M. Santos, Mercedes Amat, Núria Llor
Publikováno v:
Organic letters. 7(14)
[reaction: see text] Racemic oxodiester 1 undergoes stereoselective cyclocondensation with (S)-tryptophanol, (S)-(3,4-dimethoxyphenyl)alaninol, or the corresponding amino acids, in a process involving a tandem dynamic kinetic resolution/desymmetrizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db61daecaa804072cbd665c08caadc5a
https://pubmed.ncbi.nlm.nih.gov/15987144
https://pubmed.ncbi.nlm.nih.gov/15987144