Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Origianl Research"'
Publikováno v:
Chronic Obstr Pulm Dis
The SERPINA1 gene encodes the serine protease inhibitor alpha-1 antitrypsin (AAT) and is located on chromosome 14q31-32.3 in a cluster of homologous genes likely formed by exon duplication. AAT has a variety of anti-inflammatory properties. Its clini
Publikováno v:
Chronic Obstr Pulm Dis
Background: Hospital readmission rates are very high in patients with chronic obstructive pulmonary disease (COPD). Continuity of care (CoC) with general practitioners (GPs) and ambulatory specialists can impact readmission rates. This study aimed to
Autor:
Laura C, Myers, Richard K, Murray, Bonnie M K, Donato, Vincent X, Liu, Patricia, Kipnis, Asif, Shaikh, Jessica, Franchino-Elder
Publikováno v:
Chronic Obstr Pulm Dis
Background: It is unclear whether persistent inhaled steroid exposure in chronic obstructive pulmonary disease (COPD) patients before coronavirus disease 2019 (COVID-19) is associated with hospitalization risk. Objective: Our objective was to examine
Autor:
Richard H. Zou, S. Mehdi Nouraie, Harry B. Rossiter, Merry-Lynn McDonald, Dawn L. DeMeo, Stefanie Mason, George R. Washko, Punam K. Saha, Barry J. Make, Richard Casaburi, Elizabeth A. Regan, Jessica Bon
Publikováno v:
Chronic Obstr Pulm Dis
Introduction: Smokers with chronic obstructive pulmonary disease (COPD) are at increased risk of muscle weakness. There are limited data describing weakness in smokers with normal spirometry and preserved ratio-impaired spirometry (PRISm), 2 subgroup
Autor:
Mudiaga O. Sowho, Abigail L. Koch, Nirupama Putcha, Han Woo, Amanda Gassett, Laura M. Paulin, Kirsten Koehler, R. Graham Barr, Alejandro P. Comellas, Christopher B. Cooper, Igor Barjaktarevic, Michelle R. Zeidler, Martha E. Billings, Russell P. Bowler, MeiLan K. Han, Victor Kim, Robert Paine III, Trisha M. Parekh, Jerry A. Krishnan, Stephen P. Peters, Prescott G. Woodruff, Aaron M. Baugh, Joel D. Kaufman, David Couper, Nadia N. Hansel
Publikováno v:
Chronic Obstr Pulm Dis
Rationale: Ambient air pollution exposure is associated with respiratory morbidity among individuals with chronic obstructive pulmonary disease (COPD), particularly among those with concomitant obesity. Although people with COPD report high incidence
Autor:
Zhang, William Z., LaBedz, Stephanie L., Holbrook, Janet T., Gangemi, Andrew, Baalachandran, Ramasubramanian, Eakin, Michelle N., Wise, Robert A., Sumino, Kaharu
Publikováno v:
Chronic Obstr Pulm Dis
Background: Patients with chronic obstructive pulmonary disease (COPD) are at higher risk for severe coronavirus disease 2019 (COVID-19). From the pandemic’s onset there has been concern regarding effects on health and well-being of high-risk patie
Autor:
Byron, Thomashow, Marjorie, Stiegler, Gerard J, Criner, Mark T, Dransfield, David M G, Halpin, MeiLan K, Han, Peter, Lange, Fernando J, Martinez, Dawn, Midwinter, Dave, Singh, Maggie, Tabberer, Robert A, Wise, David A, Lipson, Paul, Jones
Publikováno v:
Chronic Obstr Pulm Dis
Background: In the InforMing the PAthway of COPD Treatment (IMPACT) trial, single-inhaler fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) reduced moderate/severe exacerbation rates versus FF/VI and UMEC/VI in patients with chronic obstructiv
Publikováno v:
Chronic Obstr Pulm Dis
Rationale: High-flow nasal therapy (HFNT) has beneficial effects in patients hospitalized with acute hypoxemic respiratory failure. HFNT has not been extensively studied following hospitalization for an acute exacerbation of chronic obstructive pulmo
Autor:
Matthew, Strand, Aastha, Khatiwada, David, Baraghoshi, David, Lynch, Edwin K, Silverman, Surya P, Bhatt, Erin, Austin, Elizabeth A, Regan, Aladin M, Boriek, James D, Crapo
Publikováno v:
Chronic Obstr Pulm Dis
Understanding baseline characteristics that can predict the progression of lung disease such as chronic obstructive pulmonary disease (COPD) for current or former smokers may allow for therapeutic intervention, particularly for individuals at high ri
Autor:
Wendy Lorizio, Han Woo, Meredith C. McCormack, Chen Liu, Nirupama Putcha, Megan Wood, Timothy Green, Parisa Kaviany, Daniel Belz, Ashraf Fawzy, Sara Carson, Michelle N. Eakin, Kirsten Koehler, Nadia N. Hansel
Publikováno v:
Chronic Obstr Pulm Dis
Rationale: Poor indoor air quality has been associated with worse chronic obstructive pulmonary disease (COPD) morbidity. In-home portable air cleaners reduce indoor pollutants and could improve respiratory health. Factors associated with air cleaner