Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Orie, Hikabe"'
Autor:
Mayumi Shono, Keiko Kishimoto, Orie Hikabe, Masafumi Hayashi, Katsunori Semi, Yasuhiro Takashima, Erika Sasaki, Kiyoko Kato, Katsuhiko Hayashi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Reconstitution of the germ cell lineage using pluripotent stem cells provides a unique platform to deepen our understanding of the mechanisms underlying germ cell development and to produce functional gametes for reproduction. This study aim
Externí odkaz:
https://doaj.org/article/905c712859b44a5e8c01641c4eb7222b
Autor:
Norio Hamada, Nobuhiko Hamazaki, So Shimamoto, Orie Hikabe, Go Nagamatsu, Yuki Takada, Kiyoko Kato, Katsuhiko Hayashi
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008676 (2020)
A set of sex chromosomes is required for gametogenesis in both males and females, as represented by sex chromosome disorders causing agametic phenotypes. Although studies using model animals have investigated the functional requirement of sex chromos
Externí odkaz:
https://doaj.org/article/a31062b395124e8ca13ede1305a84b2a
Autor:
Hiromitsu Araki, Chisako Horikawa, Kinichi Nakashima, Hirohisa Kyogoku, Katsuhiko Hayashi, Harry G. Leitch, Fumihito Miura, Orie Hikabe, Norio Hamada, So Shimamoto, Tomoya S. Kitajima, Takashi Ito, Nobuhiko Hamazaki
Publikováno v:
Nature. 589:264-269
During female germline development, oocytes become a highly specialized cell type and form a maternal cytoplasmic store of crucial factors. Oocyte growth is triggered at the transition from primordial to primary follicle and is accompanied by dynamic
Autor:
Norio Hamada, Haruka Kita, Nobuhiko Hamazaki, So Shimamoto, Yohei Nishimura, Orie Hikabe, Go Nagamatsu, Katsuhiko Hayashi
Publikováno v:
Proceedings of the National Academy of Sciences. 116:12321-12326
In mammals, most immature oocytes remain dormant in the primordial follicles to ensure the longevity of female reproductive life. A precise understanding of mechanisms underlying the dormancy is important for reproductive biology and medicine. In thi
Autor:
So, Shimamoto, Yohei, Nishimura, Go, Nagamatsu, Norio, Hamada, Haruka, Kita, Orie, Hikabe, Nobuhiko, Hamazaki, Katsuhiko, Hayashi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(25)
In mammals, most immature oocytes remain dormant in the primordial follicles to ensure the longevity of female reproductive life. A precise understanding of mechanisms underlying the dormancy is important for reproductive biology and medicine. In thi
Autor:
Nobuhiko Hamazaki, Go Nagamatsu, Orie Hikabe, Yuki Takada, Norio Hamada, Kiyoko Kato, Katsuhiko Hayashi, So Shimamoto
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008676 (2020)
PLoS Genetics
PLoS Genetics
A set of sex chromosomes is required for gametogenesis in both males and females, as represented by sex chromosome disorders causing agametic phenotypes. Although studies using model animals have investigated the functional requirement of sex chromos
Publikováno v:
SC30201804130020
NARO成果DBd
C30201712200005_3141.pdf
NARO成果DBd
C30201712200005_3141.pdf
This protocol is an extension to: Nat. Protoc. 8, 1513-1524 (2013); doi: 10.1038/nprot.2013.090; published online 11 July 2013Generation of functional oocytes in culture from pluripotent stem cells should provide a useful model system for improving o
Publikováno v:
Molecular Reproduction and Development. 81:2-19
Induced pluripotent stem cells (iPSCs) are stem cells that can be artificially generated via "cellular reprogramming" using gene transduction in somatic cells. iPSCs have enormous potential in stem-cell biology as they can give rise to numerous cell
Publikováno v:
Protocol Exchange.
Autor:
Katsuhiko Hayashi, Kinichi Nakashima, Mitinori Saitou, Yuji Hirao, So Shimamoto, Norio Hamada, Go Nagamatsu, Takuya Imamura, Yayoi Obata, Orie Hikabe, Nobuhiko Hamazaki
Publikováno v:
Nature. 539(7628)
The female germ line undergoes a unique sequence of differentiation processes that confers totipotency to the egg. The reconstitution of these events in vitro using pluripotent stem cells is a key achievement in reproductive biology and regenerative