Výsledky vyhledávání - "Oriane Scholler"

Cerebrospinal fluid and serum glycosphingolipid biomarkers in canine globoid cell leukodystrophy (Krabbe Disease)

Autor: Allison M. Bradbury, Patricia O'Donnell, Samantha J. Fisher, Evelyn M. Galban, Oriane Scholler, Jason Pinkstaff, Charles H. Vite, Jessica H. Bagel, Daniel S. Ory, Xuntian Jiang, Carley R. Corado, Chris B. Russell

Publikováno v: Mol Cell Neurosci

Globoid cell leukodystrophy (GLD, Krabbe disease, Krabbe's disease) is caused by genetic mutations in the gene encoding, galactosylceramidase (GALC). Deficiency of this enzyme results in central and peripheral nervous system pathology, and is charact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d296927a98ff9b1e4d179f0dd64941e
https://europepmc.org/articles/PMC7032565/

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Abstract B67: Correlation of pharmacokinetics (PK), pharmacodynamics (PD) and in vivo antitumor activity of BMN 673 in preclinical models

Autor: Don Musson, Ying Feng, Oriane Scholler, Huiyu Zhou, Yuqiao Shen, Leonard Post

Publikováno v: Molecular Cancer Therapeutics. 10:B67-B67

Poly (ADP-ribose) polymerase (PARP) inhibitors are emerging as an exciting class of novel chemotherapeutic agents for the treatment of cancers with specific DNA-repair defects, such as homologous recombination (HR) deficiency as a result of mutations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3071c7bd443a6581a08eb714ac1c27de
https://doi.org/10.1158/1535-7163.targ-11-b67

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