Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Oriane B. Matthys"'
Publikováno v:
Current Opinion in Biomedical Engineering. 13:160-167
The rapid progress of organoid technologies is attributable to the application of developmental biology principles, but organoid methods need further refinement provided by engineering approaches. However, we must first begin with common consensus on
Autor:
Oriane B. Matthys, Todd C. McDevitt
Publikováno v:
Methods in Molecular Biology ISBN: 9781071622605
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8da36ceaf36d83efd5ba55443d4cf067
https://doi.org/10.1007/978-1-0716-2261-2_3
https://doi.org/10.1007/978-1-0716-2261-2_3
Autor:
Charles M. Kerr, Timothy J. Kamp, Brenda M. Ogle, Martha E. Floy, Alexandra B. Steinberg, Sophie E. Givens, Ana C. Silva, Jianhua Zhang, Ying Mei, Oriane B. Matthys, Sean P. Palecek, Taylor D. Mateyka, Todd C. McDevitt
Publikováno v:
FASEB J
Cardiac fibroblasts (CFBs) support heart function by secreting extracellular matrix (ECM) and paracrine factors, respond to stress associated with injury and disease, and therefore are an increasingly important therapeutic target. We describe how dev
Autor:
David A Joy, Tracy A. Hookway, Oriane B. Matthys, Todd C. McDevitt, Reuben Thomas, Jessica E. Sepulveda
Technological advancements have enabled the design of increasingly complex engineered tissue constructs, which better mimic native tissue cellularity. Therefore, dissecting the bi-directional interactions between distinct cell types in 3D is necessar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8baed1ec0b45a564cfa2fc3a3417d174
https://doi.org/10.1101/2020.07.06.190504
https://doi.org/10.1101/2020.07.06.190504
Autor:
Michael H. Lai, Andrew P. Blair, Oriane B. Matthys, David A Joy, Benoit G. Bruneau, Michael Alexanian, Ana C. Silva, Mara A. Kauss, Todd C. McDevitt, Vaishaali Natarajan, Diwaker Turaga
Publikováno v:
Cell stem cell. 28(12)
Summary During embryogenesis, paracrine signaling between tissues in close proximity contributes to the determination of their respective cell fate(s) and development into functional organs. Organoids are in vitro models that mimic organ formation an
Autor:
Benoit G. Bruneau, Vaishaali Natarajan, Ana C. Silva, Michael Alexanian, Michael H. Lai, David A Joy, Diwakar Turaga, M.A. Kauss, Todd C. McDevitt, Oriane B. Matthys
During embryogenesis, paracrine signaling between tissues in close proximity contributes to the determination of their respective cell fate(s) and development into functional organs. Organoids arein vitromodels that mimic organ formation and cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1128982dcd466d9d4e27b864f14b15
Single-Cell Determination of Cardiac Microtissue Structure and Function Using Light Sheet Microscopy
Autor:
David A Joy, Meredith E. K. Calvert, Diwakar Turaga, Todd C. McDevitt, Tracy A. Hookway, Oriane B. Matthys
Publikováno v:
Tissue engineering. Part C, Methods. 26(4)
Native cardiac tissue is composed of heterogeneous cell populations that work cooperatively for proper tissue function; thus, engineered tissue models have moved toward incorporating multiple cardiac cell types in an effort to recapitulate native mul
Single cell determination of cardiac microtissue structure and function using light sheet microscopy
Autor:
Todd C. McDevitt, David A Joy, Meredith E. K. Calvert, Diwakar Turaga, Tracy A. Hookway, Oriane B. Matthys
Native cardiac tissue is comprised of heterogeneous cell populations that work cooperatively for proper tissue function; thus, engineered tissue models have moved toward incorporating multiple cardiac cell types in an effort to recapitulate native mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0466187497ab9e8b1d4f5fcfd2db6042
https://doi.org/10.1101/2020.01.22.915926
https://doi.org/10.1101/2020.01.22.915926
Phenotypic Variation Between Stromal Cells Differentially Impacts Engineered Cardiac Tissue Function
Autor:
David A Joy, Jessica E. Sepulveda, Tracy A. Hookway, Oriane B. Matthys, Sarah Rains, Federico N Mendoza-Camacho, Todd C. McDevitt
Publikováno v:
Tissue Eng Part A
Tissue engineering. Part A, vol 25, iss 9-10
Tissue engineering. Part A, vol 25, iss 9-10
Throughout heart development, cardiomyocytes differentiate and mature in direct contact with nonparenchymal cell types, such as cardiac fibroblasts. Thus, when modeling myocardial tissue in vitro, tissue engineers include a supporting stromal cell po
Publikováno v:
Current stem cell reports, vol 2, iss 1
Recent advances in human pluripotent stem cell (hPSC) technologies have enabled the engineering of human tissue constructs for developmental studies, disease modeling, and drug screening platforms. In vitro tissue formation can be generally described