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Akademický článek
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Autor:
Oriana Y. Teran, Matthew R. Zanotelli, Miao-chong Joy Lin, Richard A. Cerione, Kristin F. Wilson
Cancer cells, both within a developing tumor and during metastatic spread, encounter many stresses that require adaptive mechanisms to survive and maintain malignant progression. Here we describe a signaling complex involving the small GTPase Cdc42 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::660736ab97cc7695fb1621f9244cd1a4
https://doi.org/10.1101/2023.01.03.522657
https://doi.org/10.1101/2023.01.03.522657
Autor:
Oriana Y. Teran, Miao-chong J. Lin, Matthew R. Zanotelli, Kristin F. Wilson, Richard A. Cerione
Publikováno v:
Cancer Research. 82:139-139
Akt is a well-known target of mitogenic signaling, which is activated by phosphoinositide 3-kinase, PDK1 and mTORC2, and is commonly regarded as a master regulator of cell survival. However, there is still a good deal to learn regarding how Akt can p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff431a3586b3321b4db66dfbdff51e55
https://doi.org/10.1158/1538-7445.am2022-139
https://doi.org/10.1158/1538-7445.am2022-139
Autor:
Robert Cousins, Min-Hyun Kim, Tolunay Beker Aydemir, Jinhee Kim, Oriana Y. Teran, Catalina Troche, Christiaan Leeuwenburgh
Publikováno v:
Experimental Gerontology. 85:88-94
Inflammation and zinc dyshomeostasis are two common hallmarks of aging. A major zinc transporter ZIP14 (slc39a14) is upregulated by proinflammatory stimuli, e.g. interleukin-6. We have evaluated the influence of age on the Zip14 KO phenotype using wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e315fbd4b78fe3838b2bff12d06a52
https://doi.org/10.1016/j.exger.2016.09.013
https://doi.org/10.1016/j.exger.2016.09.013
Publikováno v:
Cancer Research. 80:1447-1447
Akt is a serine/threonine protein kinase that receives signals from a plethora of external and internal stimuli in order to promote survival and regulate cellular growth and metabolism. Akt is part of the highly conserved PI3K/Akt signaling axis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48240f21aa768eb8bb823fcaee68e744
https://doi.org/10.1158/1538-7445.am2020-1447
https://doi.org/10.1158/1538-7445.am2020-1447