Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Oriana Q. H. Zinani"'
Autor:
Kemal Keseroglu, Oriana Q. H. Zinani, Sevdenur Keskin, Hannah Seawall, Eslim E. Alpay, Ertuğrul M. Özbudak
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Mutations of several genes cause incomplete penetrance and variable expressivity of phenotypes, which are usually attributed to modifier genes or gene-environment interactions. Here, we show stochastic gene expression underlies the variabili
Externí odkaz:
https://doaj.org/article/c65165bd15f749a28627def134f94a5b
Autor:
M. Fethullah Simsek, Angad Singh Chandel, Didar Saparov, Oriana Q. H. Zinani, Nicholas Clason, Ertuğrul M. Özbudak
Publikováno v:
Nature
Sequential segmentation creates modular body plans of diverse metazoan embryos(1-4). Somitogenesis establishes segmental pattern of vertebrate body axis. A molecular segmentation clock in the presomitic mesoderm (PSM) sets the pace of somite formatio
Publikováno v:
Trends Genet
Coordinated spatiotemporal expression of large sets of genes is required for the development and homeostasis of organisms. To achieve this goal, organisms use myriad strategies where they form operons, utilize bidirectional promoters, cluster genes,
Publikováno v:
Nature. 589:431-436
Gene expression is an inherently stochastic process1,2; however, organismal development and homeostasis require cells to coordinate the spatiotemporal expression of large sets of genes. In metazoans, pairs of co-expressed genes often reside in the sa