Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Oriana A. Perez"'
Autor:
Rebecca Leylek, Marcela Alcántara-Hernández, Zachary Lanzar, Anja Lüdtke, Oriana A. Perez, Boris Reizis, Juliana Idoyaga
Publikováno v:
Cell Reports, Vol 29, Iss 11, Pp 3736-3750.e8 (2019)
Summary: Plasmacytoid dendritic cells (pDCs) are sensor cells with diverse immune functions, from type I interferon (IFN-I) production to antigen presentation, T cell activation, and tolerance. Regulation of these functions remains poorly understood
Externí odkaz:
https://doaj.org/article/964c50e97b5745fd97497159e13df8b8
Autor:
Eric J. Wigton, Victoria Osorio-Vasquez, Cosmin Tegla, Oriana A. Perez, Marcus J. Hines, Tenny Mudianto, K. Mark Ansel, Maryaline Coffre, Robin Kageyama, David Benhamou, Marisella Panduro, Michael T. McManus, Sergei B. Koralov, Sofia Bajwa, Doron Melamed
Publikováno v:
Cell reports, vol 33, iss 9
Cell Rep
Cell Reports, Vol 33, Iss 9, Pp 108436-(2020)
Cell Rep
Cell Reports, Vol 33, Iss 9, Pp 108436-(2020)
Summary: The phosphatidylinositol 3-kinase (PI3K) signaling cascade downstream of the B cell receptor (BCR) signalosome is essential for B cell maturation. Proper signaling strength is maintained through the PI3K negative regulator phosphatase and te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed449654de28a33a9c20537d6c1badb
https://escholarship.org/uc/item/5847g2xz
https://escholarship.org/uc/item/5847g2xz
Autor:
Robert R. Clancy, Aristotelis Tsirigos, Peter M. Izmirly, Alireza Khodadadi-Jamayran, Asiya Seema Chida, Johannes Hartl, Stefano Volpi, Claudia Bracaglia, Gregg J. Silverman, Benjamin Sally, Ignacio Sanz, Mimi Y. Kim, Oriana A. Perez, Gian Marco Ghiggeri, Ali Rashidfarrokhi, Chetna Soni, Boris Reizis, Yueyang Wang, Ivan Caiello, H. Michael Belmont, Vanja Sisirak, Jill P. Buyon, Lee Serpas
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2021, 218 (5), ⟨10.1084/jem.20201138⟩
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2021, 218 (5), ⟨10.1084/jem.20201138⟩
Loss-of-function mutations in DNaseL13, the enzyme that restricts the amount of microparticle-associated DNA, cause SLE in humans and mice. In this issue of JEM, Hartl et al. uncover a reduction in plasma DNASE1L3 enzymatic activity due to the presen
Autor:
Tae Jin Yun, Suzu Igarashi, Haoquan Zhao, Adeeb Rahman, Donna L. Farber, Oriana A. Perez, Boris Reizis, Felicia Goodrum, Peter A. Sims, Emmanuel Zorn, Yufeng Shen, Marcus R. Pereira
Publikováno v:
Sci Immunol
Plasmacytoid dendritic cells (pDCs) can rapidly produce interferons and other soluble factors in response to extracellular viruses or virus mimics such as CpG-containing DNA. pDCs can also recognize live cells infected with certain RNA viruses, but t
Autor:
Joseph C. Devlin, Tasleem Samji, Payal Damani-Yokota, Basak B. Ural, Geunhyo Jang, Boris Reizis, Quynh Mai Pham, Stephen T. Yeung, Meike Dittmann, Catherine M. Sawai, Kamal M. Khanna, P'ng Loke, Maren de Vries, Leigh Maher, Oriana A. Perez, Paola Vera-Licona
Publikováno v:
Sci Immunol
Tissue-resident macrophages are a diverse population of cells that perform specialized functions including sustaining tissue homeostasis and tissue surveillance. Here we report an interstitial subset of CD169(+) lung-resident macrophages that are tra
Autor:
Jule Goike, Vanja Sisirak, Joseph Pucella, Krystal L. Ching, Justin Mehl, George Georgiou, William N. Voss, Oriana A. Perez, Boris Reizis, Chetna Soni, Lee Serpas, Gregory C. Ippolito
Publikováno v:
Immunity
Immunity, Elsevier, 2020, 52 (6), pp.1022-1038.e7. ⟨10.1016/j.immuni.2020.04.015⟩
Immunity, Elsevier, 2020, 52 (6), pp.1022-1038.e7. ⟨10.1016/j.immuni.2020.04.015⟩
International audience; Class-switched antibodies to double-stranded DNA (dsDNA) are prevalent and pathogenic in systemic lupus erythematosus (SLE), yet mechanisms of their development remain poorly understood. Humans and mice lacking secreted DNase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bc79749f46c927c0864b8568cc8917
https://hal.archives-ouvertes.fr/hal-03045224
https://hal.archives-ouvertes.fr/hal-03045224
Autor:
Oriana Marimon Perez
Publikováno v:
Documentos de trabajo Areandina.
El tipo de caracter investigativo tiene un enfoque para la concientizacion y la transmision significativa del conocimiento en los aspectos ecologicos de proyectos y planteamientos que se tomen ahora, no solo tienen un efecto inmediato en la sociedad,
Autor:
Ioanna Tiniakou, Margaret E. Kirkling, George S. Yap, Colleen M. Lau, Boris Reizis, Hanno Hock, Oriana A. Perez
Publikováno v:
The Journal of Experimental Medicine
Transcriptional control of dendritic cell (DC) functions is poorly understood. Lau, Tiniakou, et al. report that transcription factor ETV6 optimizes gene expression in DCs and facilitates their ability to cross-prime T cells and initiate tumor-specif
Autor:
Masato Tanaka, Stephen T. Yeung, Kamal M. Khanna, Basak B. Ural, Tasleem Samji, Pablo A. Romagnoli, Leigh Maher, Oriana A. Perez, Paola Vera-Licona
The spleen is an important site for generating protective immune responses against pathogens. After infection, immune cells undergo rapid reorganization to initiate and maintain localized inflammatory responses; however, the mechanisms governing this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922747cf717afe5f20cdfb8c9628df00
http://immunology.sciencemag.org/content/2/16/eaah5520
http://immunology.sciencemag.org/content/2/16/eaah5520
Autor:
Zachary Lanzar, Juliana Idoyaga, Anja Lüdtke, Marcela Alcántara-Hernández, Rebecca Leylek, Oriana A. Perez, Boris Reizis
Publikováno v:
Cell reports
Cell Reports, Vol 29, Iss 11, Pp 3736-3750.e8 (2019)
Cell Reports
Cell Reports, Vol 29, Iss 11, Pp 3736-3750.e8 (2019)
Cell Reports
SUMMARY Plasmacytoid dendritic cells (pDCs) are sensor cells with diverse immune functions, from type I interferon (IFN-I) production to antigen presentation, T cell activation, and tolerance. Regulation of these functions remains poorly understood b