Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Ori, Staszewski"'
Autor:
Azadeh Ebrahimi, Andrey Korshunov, Guido Reifenberger, David Capper, Joerg Felsberg, Elena Trisolini, Bianca Pollo, Chiara Calatozzolo, Marco Prinz, Ori Staszewski, Leonille Schweizer, Jens Schittenhelm, Patrick N. Harter, Werner Paulus, Christian Thomas, Patricia Kohlhof-Meinecke, Marcel Seiz-Rosenhagen, Till Milde, Belén M. Casalini, Abigail Suwala, Annika K. Wefers, Annekathrin Reinhardt, Philipp Sievers, Christof M. Kramm, Nima Etminam, Andreas Unterberg, Wolfgang Wick, Christel Herold-Mende, Dominik Sturm, Stefan M. Pfister, Martin Sill, David T. W. Jones, Daniel Schrimpf, David E. Reuss, Ken Aldape, Zied Abdullaev, Felix Sahm, Andreas von Deimling, Damian Stichel
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-10 (2022)
Abstract Pleomorphic xanthoastrocytoma (PXA) in its classic manifestation exhibits distinct morphological features and is assigned to CNS WHO grade 2 or grade 3. Distinction from glioblastoma variants and lower grade glial and glioneuronal tumors is
Externí odkaz:
https://doaj.org/article/3e45563738ca4626aad3e030dbd8c07b
Autor:
Moumita Datta, Ori Staszewski
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-7 (2021)
Abstract Objective Histone acetylation is an important mechanism in the regulation of gene expression and plays a crucial role in both cellular development and cellular response to external or internal stimuli. One key aspect of this form of regulati
Externí odkaz:
https://doaj.org/article/97ef9f3d1ee445ec98c01bc26c9d5537
Autor:
Christian Koelsche, Daniel Schrimpf, Damian Stichel, Martin Sill, Felix Sahm, David E. Reuss, Mirjam Blattner, Barbara Worst, Christoph E. Heilig, Katja Beck, Peter Horak, Simon Kreutzfeldt, Elke Paff, Sebastian Stark, Pascal Johann, Florian Selt, Jonas Ecker, Dominik Sturm, Kristian W. Pajtler, Annekathrin Reinhardt, Annika K. Wefers, Philipp Sievers, Azadeh Ebrahimi, Abigail Suwala, Francisco Fernández-Klett, Belén Casalini, Andrey Korshunov, Volker Hovestadt, Felix K. F. Kommoss, Mark Kriegsmann, Matthias Schick, Melanie Bewerunge-Hudler, Till Milde, Olaf Witt, Andreas E. Kulozik, Marcel Kool, Laura Romero-Pérez, Thomas G. P. Grünewald, Thomas Kirchner, Wolfgang Wick, Michael Platten, Andreas Unterberg, Matthias Uhl, Amir Abdollahi, Jürgen Debus, Burkhard Lehner, Christian Thomas, Martin Hasselblatt, Werner Paulus, Christian Hartmann, Ori Staszewski, Marco Prinz, Jürgen Hench, Stephan Frank, Yvonne M. H. Versleijen-Jonkers, Marije E. Weidema, Thomas Mentzel, Klaus Griewank, Enrique de Álava, Juan Díaz Martín, Miguel A. Idoate Gastearena, Kenneth Tou-En Chang, Sharon Yin Yee Low, Adrian Cuevas-Bourdier, Michel Mittelbronn, Martin Mynarek, Stefan Rutkowski, Ulrich Schüller, Viktor F. Mautner, Jens Schittenhelm, Jonathan Serrano, Matija Snuderl, Reinhard Büttner, Thomas Klingebiel, Rolf Buslei, Manfred Gessler, Pieter Wesseling, Winand N. M. Dinjens, Sebastian Brandner, Zane Jaunmuktane, Iben Lyskjær, Peter Schirmacher, Albrecht Stenzinger, Benedikt Brors, Hanno Glimm, Christoph Heining, Oscar M. Tirado, Miguel Sáinz-Jaspeado, Jaume Mora, Javier Alonso, Xavier Garcia del Muro, Sebastian Moran, Manel Esteller, Jamal K. Benhamida, Marc Ladanyi, Eva Wardelmann, Cristina Antonescu, Adrienne Flanagan, Uta Dirksen, Peter Hohenberger, Daniel Baumhoer, Wolfgang Hartmann, Christian Vokuhl, Uta Flucke, Iver Petersen, Gunhild Mechtersheimer, David Capper, David T. W. Jones, Stefan Fröhling, Stefan M. Pfister, Andreas von Deimling
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Sarcomas are morphologically heterogeneous tumours rendering their classification challenging. Here the authors developed a classifier using DNA methylation data from several soft tissue and bone sarcoma subtypes, which has the potential to improve c
Externí odkaz:
https://doaj.org/article/c88e43d5043848c8bc27777e780e6d5b
Publikováno v:
J, Vol 3, Iss 4, Pp 358-365 (2020)
Previously, we reported that microglial expression of histone deacetylases 1 and 2 (Hdac1 and Hdac2) is required for microglial maturation and modulates disease progression in a mouse model of Alzheimer’s disease. Here, we analyze the role of micro
Externí odkaz:
https://doaj.org/article/d83f1fb1e80e4ea3a17a5c9c6a1e2d1c
Autor:
Charlotte Mezö, Nikolaos Dokalis, Omar Mossad, Ori Staszewski, Jana Neuber, Bahtiyar Yilmaz, Daniel Schnepf, Mercedes Gomez de Agüero, Stephanie C. Ganal-Vonarburg, Andrew J. Macpherson, Melanie Meyer-Luehmann, Peter Staeheli, Thomas Blank, Marco Prinz, Daniel Erny
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Abstract It was recently revealed that gut microbiota promote amyloid-beta (Aβ) burden in mouse models of Alzheimer’s disease (AD). However, the underlying mechanisms when using either germ-free (GF) housing conditions or treatments with antibioti
Externí odkaz:
https://doaj.org/article/1ef4ef2c7b524187aa55817e1899a3d0
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1271-1281 (2020)
Microglia are resident immune cells in the central nervous system (CNS) that are capable of carrying out prominent and various functions during development and adulthood under both homeostatic and disease conditions. Although microglia are traditiona
Externí odkaz:
https://doaj.org/article/6db3c8b1320b4db996f458e7c79e066e
Autor:
Annekathrin Reinhardt, Damian Stichel, Daniel Schrimpf, Christian Koelsche, Annika K. Wefers, Azadeh Ebrahimi, Philipp Sievers, Kristin Huang, M. Belén Casalini, Francisco Fernández-Klett, Abigail Suwala, Michael Weller, Dorothee Gramatzki, Joerg Felsberg, Guido Reifenberger, Albert Becker, Volkmar H. Hans, Marco Prinz, Ori Staszewski, Till Acker, Hildegard Dohmen, Christian Hartmann, Werner Paulus, Katharina Heß, Benjamin Brokinkel, Jens Schittenhelm, Rolf Buslei, Martina Deckert, Christian Mawrin, Ekkehard Hewer, Ute Pohl, Zane Jaunmuktane, Sebastian Brandner, Andreas Unterberg, Daniel Hänggi, Michael Platten, Stefan M. Pfister, Wolfgang Wick, Christel Herold-Mende, Andrey Korshunov, David E. Reuss, Felix Sahm, David T. W. Jones, David Capper, Andreas von Deimling
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract In this multi-institutional study we compiled a retrospective cohort of 86 posterior fossa tumors having received the diagnosis of cerebellar glioblastoma (cGBM). All tumors were reviewed histologically and subjected to array-based methylati
Externí odkaz:
https://doaj.org/article/0096ccdbff054756ae8dadcbafbf2ff9
Autor:
Marius Schwabenland, Omar Mossad, Adam G. Peres, Franziska Kessler, Feres Jose Mocayar Maron, Laura-Adela Harsan, Thomas Bienert, Dominik von Elverfeldt, Klaus-Peter Knobeloch, Ori Staszewski, Frank L. Heppner, Marije E. C. Meuwissen, Grazia M. S. Mancini, Marco Prinz, Thomas Blank
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-6 (2019)
Externí odkaz:
https://doaj.org/article/236b33d0bdba497fb77c847152b3950b
Autor:
Ori Staszewski, Nora Hagemeyer
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-6 (2019)
Abstract Objective Recently we demonstrated that amoeboid microglia in white matter regions are essential for proper oligodendrocyte homeostasis and myelinogenesis in the first postnatal week. Amoeboid microglia in the mouse corpus callosum change th
Externí odkaz:
https://doaj.org/article/5ff96c21ca274e4aa859976620598840
Autor:
Patrick Süß, Alana Hoffmann, Tobias Rothe, Zhengyu Ouyang, Wolfgang Baum, Ori Staszewski, Georg Schett, Marco Prinz, Gerhard Krönke, Christopher K. Glass, Jürgen Winkler, Johannes C.M. Schlachetzki
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 4082-4095.e6 (2020)
Summary: Systemic immune dysregulation contributes to the development of neuropsychiatric and neurodegenerative diseases. The precise effect of chronic peripheral immune stimulation on myeloid cells across anatomical brain regions is unclear. Here, w
Externí odkaz:
https://doaj.org/article/bd22cf9222c14c19a516a5d90377ff74