Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Orhan YILMAZ"'
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 12, Pp 3197-3210 (2024)
Abstract Atopic dermatitis (AD) is a common chronic inflammatory skin disease involving complex immune dysregulation, including the OX40-OX40L pathway. Rocatinlimab and amlitelimab, monoclonal antibodies targeting OX40 and OX40L, respectively, have s
Externí odkaz:
https://doaj.org/article/3c82968962094c8792c041dae172e29e
Autor:
Orhan Yilmaz, Tiago Torres
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 9, Pp 2393-2406 (2024)
Abstract Atopic dermatitis (AD) is a chronic, inflammatory skin disease characterized by intense pruritus and eczematous lesions, significantly impacting physical health and quality of life. The pathogenesis of AD involves genetic predisposition, imm
Externí odkaz:
https://doaj.org/article/f1e28122a36b41758fc211c60f146520
Publikováno v:
Drugs in Context, Vol 13, Pp 1-24 (2024)
Psoriasis is a chronic inflammatory skin disease affecting 2–3% of the global population. Traditional systemic treatments, such as methotrexate, cyclosporine, acitretin and fumaric acid esters, have limited efficacy and are associated with signific
Externí odkaz:
https://doaj.org/article/9560566152224b9383272fb94ad653ef
Publikováno v:
Journal of International Medical Research, Vol 52 (2024)
Atopic dermatitis (AD) is a common, chronic, and recurrent inflammatory skin condition that affects a considerable portion of the population, and is particularly prevalent among children. The development of AD is influenced by environmental and genet
Externí odkaz:
https://doaj.org/article/5b8f25f5af17407aa7597a6bfb0e3879
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1841 (2024)
Atopic dermatitis is a chronic inflammatory dermatosis characterized by pruritic, scaly, erythematous lesions. Its incidence varies but is estimated to be approximately 20% in children and between 7 and 14% in adults, with variation amongst countries
Externí odkaz:
https://doaj.org/article/067d93e57bc044a681d157a966040c80
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 908 (2024)
Generalized Pustular Psoriasis (GPP) is a rare and severe subtype of psoriasis that significantly impacts patients’ quality of life. Until recently, no specific treatment modalities were available, and treatment for GPP followed the guidelines for
Externí odkaz:
https://doaj.org/article/4b0434174ceb44e9a3955c09ac893a0f
Publikováno v:
Journal of International Advanced Otology, Vol 18, Iss 6, Pp 530-536 (2022)
Externí odkaz:
https://doaj.org/article/9ed24d69c7da42fb996e0f15280e69a7
Autor:
Dan L. McElroy, Andrew J. Roebuck, Quentin Greba, Sumanta Garai, Asher L. Brandt, Orhan Yilmaz, Stuart M. Cain, Terrance P. Snutch, Ganesh A. Thakur, Robert B. Laprairie, John G. Howland
Publikováno v:
IBRO Neuroscience Reports, Vol 12, Iss , Pp 121-130 (2022)
Childhood absence epilepsy (CAE) is a non-convulsive seizure disorder primarily in children characterized by absence seizures. Absence seizures consist of 2.5–5 Hz spike-and-wave discharges (SWDs) detectable using electroencephalography (EEG). Curr
Externí odkaz:
https://doaj.org/article/b926279b3de946e6b0d7bbfc1871a059
Autor:
Kimberly A. Jett, Zakery N. Baker, Amzad Hossain, Aren Boulet, Paul A. Cobine, Sagnika Ghosh, Philip Ng, Orhan Yilmaz, Kris Barreto, John DeCoteau, Karen Mochoruk, George N. Ioannou, Christopher Savard, Sai Yuan, Osama H.M.H. Abdalla, Christopher Lowden, Byung-Eun Kim, Hai-Ying Mary Cheng, Brendan J. Battersby, Vishal M. Gohil, Scot C. Leary
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 1 (2023)
Signaling circuits crucial to systemic physiology are widespread, yet uncovering their molecular underpinnings remains a barrier to understanding the etiology of many metabolic disorders. Here, we identified a copper-linked signaling circuit activate
Externí odkaz:
https://doaj.org/article/018c1e9c28eb4a92a02a5abcb7afd106
Autor:
Xiaojie Luan, George Belev, Julian S. Tam, Santosh Jagadeeshan, Noman Hassan, Paula Gioino, Nikolay Grishchenko, Yanyun Huang, James L. Carmalt, Tanya Duke, Teela Jones, Bev Monson, Monique Burmester, Tomer Simovich, Orhan Yilmaz, Veronica A. Campanucci, Terry E. Machen, L. Dean Chapman, Juan P. Ianowski
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Cystic fibrosis is caused by mutations in the CFTR chloride channel, leading to reduced airway surface liquid secretion. Here the authors show that exposure to bacteria triggers secretion in wild-type but not in pig models of cystic fibrosis, suggest
Externí odkaz:
https://doaj.org/article/b1726fa086ae482099aa7acc7f31f83b