Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Orhan Rasid"'
Autor:
Wenyang Dong, Orhan Rasid, Christine Chevalier, Michael Connor, Matthew J.G. Eldridge, Melanie Anne Hamon
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 4016-4026.e4 (2020)
Summary: Pathogenic bacteria can alter host gene expression through post-translational modifications of histones. We show that a natural colonizer, Streptococcus pneumoniae, induces specific histone modifications, including robust dephosphorylation o
Externí odkaz:
https://doaj.org/article/44f0c95bcbf74b7abfb2d660e701bf50
Autor:
Edith Gouin, Damien Balestrino, Orhan Rasid, Marie-Anne Nahori, Véronique Villiers, Francis Impens, Stevenn Volant, Thomas Vogl, Yves Jacob, Olivier Dussurget, Pascale Cossart
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT Listeria monocytogenes is a pathogenic bacterium causing potentially fatal foodborne infections in humans and animals. While the mechanisms used by Listeria to manipulate its host have been thoroughly characterized, how the host controls bac
Externí odkaz:
https://doaj.org/article/581f08c8189d4367abe55222fb84327f
Autor:
Orhan Rasid, Christine Chevalier, Tiphaine Marie-Noelle Camarasa, Catherine Fitting, Jean-Marc Cavaillon, Melanie Anne Hamon
Publikováno v:
Cell Reports, Vol 29, Iss 12, Pp 3933-3945.e3 (2019)
Summary: Natural killer (NK) cells are unique players in innate immunity and, as such, an attractive target for immunotherapy. NK cells display immune memory properties in certain models, but the long-term status of NK cells following systemic inflam
Externí odkaz:
https://doaj.org/article/f43df46125154cb4a2112aa02b25e9ca
Autor:
Mark S. Gresnigt, Cristina Cunha, Martin Jaeger, Samuel M. Gonçalves, R. K. Subbarao Malireddi, Anne Ammerdorffer, Rosalie Lubbers, Marije Oosting, Orhan Rasid, Grégory Jouvion, Catherine Fitting, Dirk J. de Jong, João F. Lacerda, António Campos, Willem J. G. Melchers, Katrien Lagrou, Johan Maertens, Thirumala-Devi Kanneganti, Agostinho Carvalho, Oumaima Ibrahim-Granet, Frank L. van de Veerdonk
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
NOD2 has been shown to be crucial for immune recognition of Aspergillus infection. Here the authors show that a common NOD2 genetic variant associated with Crohn’s disease is associated with reduced risk of disease due to enhanced antifungal activa
Externí odkaz:
https://doaj.org/article/b13bbdc0097e4f22afcd8c24f2411e03
Autor:
Ignacio Santecchia, Frédérique Vernel-Pauillac, Orhan Rasid, Jessica Quintin, Maria Gomes-Solecki, Ivo G Boneca, Catherine Werts
Publikováno v:
PLoS Pathogens, Vol 15, Iss 5, p e1007811 (2019)
Leptospira interrogans are pathogenic spirochetes responsible for leptospirosis, a worldwide reemerging zoonosis. Many Leptospira serovars have been described, and prophylaxis using inactivated bacteria provides only short-term serovar-specific prote
Externí odkaz:
https://doaj.org/article/5ad4ef85cad449cb953accca0b741457
Autor:
Mark S. Gresnigt, Martin Jaeger, R. K. Subbarao Malireddi, Orhan Rasid, Grégory Jouvion, Catherine Fitting, Willem J. G. Melchers, Thirumala-Devi Kanneganti, Agostinho Carvalho, Oumaima Ibrahim-Granet, Frank L. van de Veerdonk
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
One of the major life-threatening infections for which severely immunocompromised patients are at risk is invasive aspergillosis (IA). Despite the current treatment options, the increasing antifungal resistance and poor outcome highlight the need for
Externí odkaz:
https://doaj.org/article/00586c1236914765882d64088a249774
Autor:
Orhan Rasid, Véronique Mériaux, Erin M Khan, Chloé Borde, Ioana S Ciulean, Catherine Fitting, Bénédicte Manoury, Jean-Marc Cavaillon, Noëlle Doyen
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 5, p e0004716 (2016)
A critical role for intracellular TLR9 has been described in recognition and host resistance to Leishmania parasites. As TLR9 requires endolysosomal proteolytic cleavage to achieve signaling functionality, we investigated the contribution of differen
Externí odkaz:
https://doaj.org/article/bca00c507b58435996ee66f1db7c9826
Autor:
Amélie Savers, Orhan Rasid, Marianna Parlato, Matthias Brock, Gregory Jouvion, Bernhard Ryffel, Jean-Marc Cavaillon, Gerard Eberl, Oumaïma Ibrahim-Granet
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153829 (2016)
Phagocytes restrict the germination of Aspergillus fumigatus conidia and prevent the establishment of invasive pulmonary aspergillosis in immunecompetent mice. Here we report that immunecompetent mice recovering from a primary A. fumigatus challenge
Externí odkaz:
https://doaj.org/article/18871e35acec4b7091887cd6d507fcf1
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95378 (2014)
Proteasomes play a fundamental role in intracellular protein degradation and therewith regulate a variety of cellular processes. Exposure of cells to (pro)inflammatory cytokines upregulates the expression of three inducible catalytic proteasome subun
Externí odkaz:
https://doaj.org/article/6256ed97b95a40d49593c2a16a355e7b
Autor:
Caroline Chauché, Orhan Rasid, Anne‐Marie Donachie, Caitlin M. McManus, Stephan Löser, Tiffany Campion, Josh Richards, Danielle J. Smyth, Henry J. McSorley, Rick M. Maizels
Publikováno v:
Immunology. 167:197-211
Type 2-high asthma is a chronic inflammatory disease of the airways which is increasingly prevalent in countries where helminth parasite infections are rare, and characterized by T helper 2 (Th2)-dependent accumulation of eosinophils in the lungs. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bfffa352a5ccb45849a6b6748ac2ec0
https://doi.org/10.1111/imm.13528
https://doi.org/10.1111/imm.13528