Zobrazeno 1 - 10
of 1 779
pro vyhledávání: '"Orhan K"'
Autor:
Katie Rubitschung, Amber Sherwood, Rasesh Kapadia, Yin Xi, Asghar Hajibeigi, Katya B Rubinow, Joseph E Zerwekh, Orhan K Öz
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0296390 (2024)
Estradiol is an important regulator of bone accumulation and maintenance. Circulating estrogens are primarily produced by the gonads. Aromatase, the enzyme responsible for the conversion of androgens to estrogen, is expressed by bone marrow cells (BM
Externí odkaz:
https://doaj.org/article/efec4e92327f450db54d0cee9fa0d877
Autor:
Aditi Mulgaonkar, Durga Udayakumar, Yaxing Yang, Shelby Harris, Orhan K. Öz, Praveen Ramakrishnan Geethakumari, Xiankai Sun
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Chimeric antigen receptor (CAR) T-cell therapies have evolved as breakthrough treatment options for the management of hematological malignancies and are also being developed as therapeutics for solid tumors. However, despite the impressive patient re
Externí odkaz:
https://doaj.org/article/f1f1996dcbf2454e873de44322b482f4
Autor:
Melike Can, Tugce Sengül, Secil Akyildiz Demir, Orhan K. İnci, Hande Basırlı, Volkan Seyrantepe
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Introduction: Tay–Sachs disease is an autosomal recessively inherited lysosomal storage disease that results from loss-of-function mutations in the HEXA gene coding β-hexosaminidase A. HEXA gene deficiency affects the central nervous system owing
Externí odkaz:
https://doaj.org/article/9b1293ecff614b7da31e20e3327be828
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Copper-67 (t1/2 = 2.58 days) decays by β− ( $$\text{E}_{{\upbeta^{-}\text{max}}}$$ E β - max : 562 keV) and γ-rays (93 keV and 185 keV) rendering it with potential for both radionuclide therapy and single-photon emission computed tomogr
Externí odkaz:
https://doaj.org/article/bd8333e81bf24b33981c236b7c5fe9b7
Autor:
Naim M. Maalouf, Avneesh Chhabra, Jason Zafereo, Ross Querry, Dwight A. Towler, Uma J. Thakur, Joseph Frankl, John R. Poindexter, Bayan Mogharrabi, May Xac, Orhan K. Öz, Craig D. Rubin
Publikováno v:
JBMR Plus, Vol 6, Iss 1, Pp n/a-n/a (2022)
ABSTRACT Androgen deprivation therapy (ADT) is a cornerstone of advanced prostate cancer (PCa) therapy. Its use is associated with a loss of bone mineral density (BMD) and a greater risk of falls and osteoporotic fractures. In this prospective cohort
Externí odkaz:
https://doaj.org/article/ba243cf05fe844e882cc911d182f738a
Autor:
Thomas Pacicco, Shayna Ratner, Yin Xi, Takeshi Yokoo, David Fetzer, Orhan K Oz, Craig D Rubin, Avneesh Chhabra
Publikováno v:
Indian Journal of Radiology and Imaging, Vol 29, Iss 02, Pp 155-162 (2019)
Purpose: To evaluate interreader performance in the measurement of the cross-sectional area and myosteatosis of pelvic skeletal muscles using fat quantification magnetic resonance imaging (MRI) and correlate with patient anthropomorphic characteristi
Externí odkaz:
https://doaj.org/article/3187b17f61f04c2aac9702b45ce706d0
Autor:
Roberta S. Santos, Aaron P. Frank, Luciana A. Fátima, Biff F. Palmer, Orhan K. Öz, Deborah J. Clegg
Publikováno v:
Molecular Metabolism, Vol 18, Iss , Pp 51-59 (2018)
Objectives: Brown adipose tissue (BAT) and BAT-like adipose tissues, referred to as ‘beige’ adipose tissues uncouple respiration from ATP synthesis via uncoupling protein one (UCP-1). There is a sexual dimorphism with respect to beige and BAT tis
Externí odkaz:
https://doaj.org/article/6c3928e0f6d44d7286faaa978b65117f
Autor:
Na Li, Shangang Zhao, Zhuzhen Zhang, Yi Zhu, Christy M Gliniak, Lavanya Vishvanath, Yu A An, May-yun Wang, Yingfeng Deng, Qingzhang Zhu, Bo Shan, Amber Sherwood, Toshiharu Onodera, Orhan K Oz, Ruth Gordillo, Rana K Gupta, Ming Liu, Tamas L Horvath, Vishwa Deep Dixit, Philipp E Scherer
Publikováno v:
eLife, Vol 10 (2021)
Adiponectin is essential for the regulation of tissue substrate utilization and systemic insulin sensitivity. Clinical studies have suggested a positive association of circulating adiponectin with healthspan and lifespan. However, the direct effects
Externí odkaz:
https://doaj.org/article/cc9c31e77b504b8e89c7e9bde51878cd
Autor:
Joseph A. Frankl, Yu An, Amber Sherwood, Guiyang Hao, Feng-Yun Huang, Pawan Thapa, Deborah J. Clegg, Xiankai Sun, Philipp E. Scherer, Orhan K. Öz
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4880 (2022)
Obesity is a leading cause of preventable death and morbidity. To elucidate the mechanisms connecting metabolically active brown adipose tissue (BAT) and metabolic health may provide insights into methods of treatment for obesity-related conditions.
Externí odkaz:
https://doaj.org/article/71e8a0b270084dfcb80f9fe72f709e60
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227830 (2020)
Estrogens are important for maintaining metabolic health in males. However, the key sources of local estrogen production for regulating energy metabolism have not been fully defined. Immune cells exhibit aromatase activity and are resident in metabol
Externí odkaz:
https://doaj.org/article/53f402a55b064808a1112826da71d4a5