Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Orhan G. Yigitbasi"'
Autor:
Maher N. Youne, Orhan G. Yigitbasi, Steven I. Sherman, Mahitosh Mandal, Bradley A. Schiff, FChristopher C. Holsinger, Benjamin N. Bekele, Sai Ching Yeung, Adel K. El-Naggar, Ge Zhou, Samar A. Jasser, Jeffrey N. Myers, Dao Doan, Andrea B. McMurphy, Seungwon Kim
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(15)
Autor:
James Ludwick, Mahitosh Mandal, Gordon B. Mills, Maher N. Younes, Jeffrey N. Myers, Dao Doan, Orhan G. Yigitbasi, Samar A. Jasser, Adel K. El-Naggar, Andrea Barber McMurphey, Eric A. Swan, Cora Bucana
Publikováno v:
Oral Oncology. 42:430-439
Therapies that target signaling pathways critical to the pathogenesis and progression of squamous cell carcinoma of the head and neck (HNSCC) are needed. One such target, phosphatidylinositol 3-kinase, and its downstream target serine/threonine kinas
Autor:
Mahitosh Mandal, Samar A. Jasser, Adel K. El-Naggar, Bradley A. Schiff, Gordon B. Mills, Benjamin N. Bekele, Yasemin D. Yazici, Jeffrey N. Myers, Orhan G. Yigitbasi, Maher N. Younes, Seungwon Kim
Publikováno v:
Molecular Cancer Therapeutics. 4:1146-1156
We investigated integrin-linked kinase (ILK), a focal adhesion serine-threonine protein kinase, as a new molecular target for treating anaplastic thyroid cancer. ILK mediates cell growth and survival signals and is overexpressed in a number of cancer
Autor:
Benjamin N. Bekele, Isaiah J. Fidler, Mahitosh Mandal, Yasemin D. Yazici, Samar A. Jasser, Sun Jin Kim, Valerie S. Hawthorne, Young Wook Park, Corazon D. Bucana, Maher N. Younes, Jeffrey N. Myers, Orhan G. Yigitbasi
Publikováno v:
Cancer Research. 65:4716-4727
Patients suffering from bone metastases of follicular thyroid carcinoma (FTC) have a poor prognosis because of the lack of effective treatment strategies. The overexpression of epidermal growth factor receptor (EGFR) associated with increased vascula
Autor:
Jeffrey N. Myers, Samar A. Jasser, Young Wook Park, Corazon D. Bucana, Orhan G. Yigitbasi, Benjamin N. Bekele, Ge Zhou, Maher N. Younes
Publikováno v:
Clinical Cancer Research. 11:1963-1973
Purpose: We investigated whether concomitant blockade of the epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR) signaling pathways by AEE788, a dual inhibitor of EGFR and VEGFR tyrosine kinases, would inhi
Publikováno v:
Saudi medical journal. 30(7)
To retrospectively analyze the extraordinary pathologic entities inside the concha bullosa (CB).Surgical interventions were performed on 136 patients (234 CB) at the Department of Ear, Nose, and Throat, and Head and Neck Surgery, Izmir Tepecik Traini
Autor:
Cora Bucana, Samar A. Jasser, Maher N. Younes, Jeffrey N. Myers, Orhan G. Yigitbasi, Yasemin D. Yazici, Gordon B. Mills, Adel K. El-Naggar
Publikováno v:
Archives of otolaryngology--headneck surgery. 133(1)
Objective To study the expression of integrin-linked kinase (ILK) in human squamous cell carcinoma of the head and neck (SCCHN) tumor specimens and cell lines and the efficacy of the novel small molecule QLT0267. Design Immunohistochemical analysis o
Autor:
Samar A. Jasser, Jeffrey N. Myers, Dao Doan, Orhan G. Yigitbasi, Mahitosh Mandal, Seungwon Kim, Bradley A. Schiff, B. Nebiyou Bekele
Publikováno v:
Molecular cancer therapeutics. 4(4)
Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human malignancies with a mean survival of only 6 months. The poor prognosis of patients with ATC reflects the current lack of curative therapeutic options and the need for development
Autor:
Ge Zhou, Mahitosh Mandal, Sai Ching J. Yeung, Samar A. Jasser, Jeffrey N. Myers, Dao Doan, Andrea B. McMurphy, Orhan G. Yigitbasi, Seungwon Kim, Benjamin N. Bekele, F. Christopher Holsinger, Adel K. El-Naggar, Steven I. Sherman, Maher N. Younes, Bradley A. Schiff
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 10(24)
Purpose: No effective treatment options currently are available to patients with anaplastic thyroid cancer (ATC), resulting in high mortality rates. Epidermal growth factor (EGF) has been shown to play a role in the pathogenesis of many types of canc