Zobrazeno 1 - 10
of 1 758
pro vyhledávání: '"Organotypic-culture"'
Autor:
Akina Mori, Marjolein Vermeer, Lenie J. van den Broek, Jeroen Heijmans, Arnaud Nicolas, Josse Bouwhuis, Todd Burton, Kazushi Matsumura, Kazuhiro Ohashi, Shigeaki Ito, Bart Kramer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Airway inflammation, a protective response in the human body, can disrupt normal organ function when chronic, as seen in chronic obstructive pulmonary disease (COPD) and asthma. Chronic bronchitis induces goblet cell hyperplasia and metaplas
Externí odkaz:
https://doaj.org/article/4acd63646b44459f875e9616d74284d6
Autor:
Yuka Aizawa, Kenta Haga, Nagako Yoshiba, Witsanu Yortchan, Sho Takada, Rintaro Tanaka, Eriko Naito, Tatsuya Abé, Satoshi Maruyama, Manabu Yamazaki, Jun-ichi Tanuma, Kazuyo Igawa, Kei Tomihara, Shinsaku Togo, Kenji Izumi
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2373 (2024)
Background/Objectives: Cancer organoids have emerged as a valuable tool of three-dimensional (3D) cell cultures to investigate tumor heterogeneity and predict tumor behavior and treatment response. We developed a 3D organotypic culture model of oral
Externí odkaz:
https://doaj.org/article/a0dcf2c11ca447718b24c4b0f0cb8cf8
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Introduction: Recent advances have enabled organotypic culture of beating human myocardial slices that are stable for weeks. However, human myocardial samples are rare, exhibit high variability and frequently originate from diseased hearts. Thus, the
Externí odkaz:
https://doaj.org/article/1fdc341f37ce44d291dcf8b0a66c5350
Publikováno v:
Journal of Biological Engineering, Vol 17, Iss 1, Pp 1-13 (2023)
Abstract The basic idea behind the use of 3-dimensional (3D) tools in biomedical research is the assumption that the structures under study will perform at the best in vitro if cultivated in an environment that is as similar as possible to their natu
Externí odkaz:
https://doaj.org/article/bfb0b8b3de8d43aa9bb5bbaa0df8e914
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTEnteric bacterial infections contribute substantially to global disease burden and mortality, particularly in the developing world. In vitro 2D monolayer cultures have provided critical insights into the fundamental virulence mechanisms of a
Externí odkaz:
https://doaj.org/article/486b5dc2b74d4d369b08173258974272
Publikováno v:
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, Vol 29, Iss 3, Pp 40-45 (2022)
Introduction. Melatonin, being a powerful endogenous antioxidant, provides healthy course of pregnancy and childbirth. Decrease of melatonin levels in blood correlates with severity of preeclampsia. Currently, melatonin is viewed as a perspective ant
Externí odkaz:
https://doaj.org/article/a4ccd6cc42a14abb8463f79c3010fc7e
Autor:
Una Rastovic, Sergio Francesco Bozzano, Antonio Riva, Arturo Simoni-Nieves, Nicola Harris, Rosa Miquel, Carolin Lackner, Yoh Zen, Ane Zamalloa, Krishna Menon, Nigel Heaton, Shilpa Chokshi, Elena Palma
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 150 (2023)
Alcohol-related liver disease (ALD) encompasses a range of pathological conditions that are complex to study at the clinical and preclinical levels. Despite the global burden of ALD, there is a lack of effective treatments, and mortality is high. One
Externí odkaz:
https://doaj.org/article/145c018b4afe4db7afdaef938f6c9ff3
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