Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Organoids/virology"'
Publikováno v:
Stem Cell Reports
Many pathogenic viruses that affect man display species specificity, limiting the use of animal models. Studying viral biology and identifying potential treatments therefore benefits from the development of in vitro cell systems that closely mimic hu
Autor:
Tokameh Mahmoudi, Monique M.A. Verstegen, Tanvir Hossain, Pantelis Hatzis, Robert P. de Vries, Jan Nm IJzermans, Mir M. Khalid, Elisa De Crignis, Shahla Romal, Tsung Wai Kan, Helmuth Gehart, Christina Koutsothanassis, Luc J. W. van der Laan, Shringar Rao, Meritxell Huch, Farzin Pourfarzad, Robert-Jan Palstra, Sylvia F. Boj, Charles A. Boucher, Panagiotis Moulos, Ameneh Bazrafshan, Fabrizia Carofiglio, Hans Clevers
Publikováno v:
eLife, Vol 10 (2021)
eLife, 10. eLife Sciences Publications
eLife, 10
eLife
eLife, 10. eLife Sciences Publications
eLife, 10
eLife
The molecular events that drive hepatitis B virus (HBV)-mediated transformation and tumorigenesis have remained largely unclear, due to the absence of a relevant primary model system. Here we propose the use of human liver organoids as a platform for
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 6 (2021)
DMM Disease Models and Mechanisms, 14(6):dmm049060. Company of Biologists Ltd
Disease Models & Mechanisms
article-version (VoR) Version of Record
DMM Disease Models and Mechanisms, 14(6):dmm049060. Company of Biologists Ltd
Disease Models & Mechanisms
article-version (VoR) Version of Record
The COVID-19 pandemic has emphasised the need to develop effective treatments to combat emerging viruses. Model systems that poorly represent a virus' cellular environment, however, may impede research and waste resources. Collaborations between cell
Autor:
Dasja Pajkrt, Sylvie M. Koekkoek, Hans Clevers, Norman Sachs, Gerrit Koen, Katja C. Wolthers, Sabine M. G. van der Sanden
Publikováno v:
Emerging Microbes & Infections
Emerging Microbes & Infections, 7(1). Nature Publishing Group
Emerging Microbes and Infections, 7(1). Nature Publishing Group
Emerging microbes and infections, 7(1):00772. Nature Publishing Group
Emerging Microbes & Infections, 7(1). Nature Publishing Group
Emerging Microbes and Infections, 7(1). Nature Publishing Group
Emerging microbes and infections, 7(1):00772. Nature Publishing Group
Human enteroviruses frequently cause severe diseases in children. Human enteroviruses are transmitted via the fecal-oral route and respiratory droplets, and primary replication occurs in the gastro-intestinal and respiratory tracts; however, how ente