Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Organ Toxicity and Mechanisms"'
Publikováno v:
Archives of Toxicology
Organophosphorus compound pesticides (OP) are widely used in pest control and might be misused for terrorist attacks. Although acetylcholinesterase (AChE) inhibition is the predominant toxic mechanism, OP may induce pneumonia and formation of lung ed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c467889720c9c985a6764ff73a94e7
https://doi.org/10.1007/s00204-021-03186-x
https://doi.org/10.1007/s00204-021-03186-x
Autor:
Julia Hoeng, Sophie Scheuner, Stephanie Johne, Claudius Pak, Emmanuel Guedj, Athanasios Kondylis, Dariusz Peric, Fabio Maranzano, Romain Piault, Walter K. Schlage, Nikolai V. Ivanov, Thomas Schneider, Carine Poussin, Marco van der Toorn, Rebecca Savioz, Manuel C. Peitsch, Moran Morelli, Anne-Laure Egesipe, Shoaib Majeed, Remi Dulize, Celine Merg
Publikováno v:
Archives of Toxicology
Aging and smoking are major risk factors for cardiovascular diseases (CVD). Our in vitro study compared, in the context of aging, the effects of the aerosol of Tobacco Heating System 2.2 (THS; an electrically heated tobacco product) and 3R4F referenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd36e7a5e84bef9b672dee515ef85d8
https://doi.org/10.1007/s00204-021-03123-y
https://doi.org/10.1007/s00204-021-03123-y
Autor:
Johanna Ebmeyer, Dirk Schaudien, Otto Creutzenberg, Georgia Guenther, Jan G. Hengstler, Albert Braeuning, Stefanie Hessel-Pras, Heike Sprenger, J.D. Rasinger, Julia Buchmueller
Publikováno v:
Archives of toxicology, 95(8):2785-2796
Archives of Toxicology
Archives of Toxicology
Pyrrolizidine alkaloids (PAs) are secondary plant metabolites synthesized by a wide range of plants as protection against herbivores. These toxins are found worldwide and pose a threat to human health. PAs induce acute effects like hepatic sinusoidal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82aa67b4c06c5449febce18cdaca3723
https://doi.org/10.1007/s00204-021-03108-x
https://doi.org/10.1007/s00204-021-03108-x
Autor:
Boglárka Csupor-Löffler, László Virág, János Prorok, András Varró, István Baczkó, Bence József Pászti, Péter Orvos, Dezső Csupor, Leila Topal, Ákos Bajtel, Norbert Jost, Muhammad Naveed, Tivadar Kiss
Publikováno v:
Archives of Toxicology
Cannabis use is associated with known cardiovascular side effects such as cardiac arrhythmias or even sudden cardiac death. The mechanisms behind these adverse effects are unknown. The aim of the present work was to study the cellular cardiac electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2b19b1991ecfdca19cc4a737f24a69
https://doi.org/10.1007/s00204-021-03086-0
https://doi.org/10.1007/s00204-021-03086-0
Autor:
Walter K. Schlage, Julia Hoeng, Dariusz Peric, Nicolas Sierro, John H. Miller, Ee Tsin Wong, Blaine Phillips, Justyna Szostak, Jingjie Zhang, Emmanuel Guedj, Patrick Vanscheeuwijck, Jovan Simicevic, Tom Lee, Manuel C. Peitsch, Patrice Leroy, Remi Dulize, Maica Corciulo, Oksana Lavrynenko, Yang Xiang, Kyeonghee Monica Lee, David Bornand, Bjoern Titz, Sin Kei Wong, Karsta Luettich, Mohamed Amin Choukrallah, Arkadiusz K. Kuczaj, Guo Jie Loh, Thomas Schneider, Nikolai V. Ivanov, Mehdi Auberson, Celine Merg, Ansgar Buettner
Publikováno v:
Archives of Toxicology
Cigarette smoking is the major cause of chronic obstructive pulmonary disease. Considerable attention has been paid to the reduced harm potential of nicotine-containing inhalable products such as electronic cigarettes (e-cigarettes). We investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4eabf5cd6852f8ca815167b04b5119
http://europepmc.org/articles/PMC8113187
http://europepmc.org/articles/PMC8113187
Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney
Autor:
Jan G. Hengstler, Wiebke Albrecht, Abdel-latif Seddek, Ute Hofmann, Reham Hassan, Gisela H. Degen, Lars Kuepfer, Benedikt Cramer, Stefan Hoehme, Adrian Friebel, Peter Boor, Hans-Ulrich Humpf, Maiju Myllys, Ahmed Ghallab, Albert Braeuning
Publikováno v:
Archives of Toxicology
Archives of toxicology, 95:2163–2177
Archives of toxicology, 95:2163–2177
Local accumulation of xenobiotics in human and animal tissues may cause adverse effects. Large differences in their concentrations may exist between individual cell types, often due to the expression of specific uptake and export carriers. Here we es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c635252774550d6dfe0df47b07e4dd6
http://europepmc.org/articles/PMC8166722
http://europepmc.org/articles/PMC8166722
Autor:
Rui Xiong, Levan Muskhelishvili, Tao Chen, Yue Wu, Qiangen Wu, Xuefei Cao, Priya Tripathi, Hans Rosenfeldt, Kelly Davis, Matthew Bryant, Sheila M Healy, Ying Chen
Publikováno v:
Archives of Toxicology
Exposure to cigarette smoke (CS) is a known risk factor in the pathogenesis of smoking-caused diseases, such as chronic obstructive pulmonary diseases (COPD) and lung cancer. To assess the effects of CS on the function and phenotype of airway epithel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb66957f0da802fc8331573af7bb510
https://doi.org/10.1007/s00204-021-03008-0
https://doi.org/10.1007/s00204-021-03008-0
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Archives of toxicology, 95(3), 1003-1021. SPRINGER HEIDELBERG
Archives of Toxicology
Universidad de Barcelona
Archives of toxicology, 95(3), 1003-1021. SPRINGER HEIDELBERG
Archives of Toxicology
The peripheral auditory and vestibular systems rely on sensorineural structures that are vulnerable to ototoxic agents that cause hearing loss and/or equilibrium deficits. Although attention has focused on hair cell loss as the primary pathology unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52f2fcbc1a2a13b61e3ff46f2fc5df9
https://doi.org/10.1007/s00204-020-02962-5
https://doi.org/10.1007/s00204-020-02962-5
Autor:
Jimmy Alarcan, Albert Braeuning, Claudia Luckert, Alfonso Lampen, Philip Marx-Stoelting, Heike Sprenger, Dajana Lichtenstein, Julia Waizenegger
Publikováno v:
Archives of Toxicology
Co-occurrence of pesticide residues in food commodities raises a potential safety issue as their mixture effects on human health are largely unknown. In a previous study, we reported the toxicological effects (pathology and histopathology) of imazali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e0504d2419bd1c295b874359dbd12a
http://europepmc.org/articles/PMC7904562
http://europepmc.org/articles/PMC7904562
Autor:
Satoru Takahashi, Ranchana Yeewa, Taku Naiki, Hiroyuki Kato, Yoshinaga Aoyama, Aya Naiki-Ito, Yuko Nagayasu, Shingo Inaguma, Shugo Suzuki
Publikováno v:
Archives of Toxicology
Non-alcoholic steatohepatitis (NASH) is a recognized risk factor for liver fibrosis and malignancies, and is associated with features of metabolic syndrome, such as obesity and insulin resistance (IR). We previously demonstrated that the disturbance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e7b04716babdbe8686b49348a71887
http://europepmc.org/articles/PMC7655588
http://europepmc.org/articles/PMC7655588