Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Orestis Faklaris"'
Autor:
Alexandra Botté, Jeanne Lainé, Laura Xicota, Xavier Heiligenstein, Gaëlle Fontaine, Amal Kasri, Isabelle Rivals, Pollyanna Goh, Orestis Faklaris, Jack-Christophe Cossec, Etienne Morel, Anne-Sophie Rebillat, Dean Nizetic, Graça Raposo, Marie-Claude Potier
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-22 (2020)
Abstract Enlarged early endosomes have been visualized in Alzheimer’s disease (AD) and Down syndrome (DS) using conventional confocal microscopy at a resolution corresponding to endosomal size (hundreds of nm). In order to overtake the diffraction
Externí odkaz:
https://doaj.org/article/26fd67e10b014d1ab8afbad372ac26f6
Autor:
Nilda Vanesa Ayala-Nunez, Gautier Follain, François Delalande, Aurélie Hirschler, Emma Partiot, Gillian L. Hale, Brigid C. Bollweg, Judith Roels, Maxime Chazal, Florian Bakoa, Margot Carocci, Sandrine Bourdoulous, Orestis Faklaris, Sherif R. Zaki, Anita Eckly, Béatrice Uring-Lambert, Frédéric Doussau, Sarah Cianferani, Christine Carapito, Frank M. J. Jacobs, Nolwenn Jouvenet, Jacky G. Goetz, Raphael Gaudin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Zika virus (ZIKV) can infect the central nervous system, but it is not clear how it reaches the brain. Here, Ayala-Nunez et al. show in ex vivo and in vivo models that ZIKV can hitch a ride in monocytes in a Trojan Horse manner to cross the endotheli
Externí odkaz:
https://doaj.org/article/80c8125c989f4ad684da8d5bd8592317
Autor:
Gloria Gonzalez Curto, Audrey Der Vartanian, Youcef El-Mokhtar Frarma, Line Manceau, Lorenzo Baldi, Selene Prisco, Nabila Elarouci, Frédéric Causeret, Daniil Korenkov, Muriel Rigolet, Frédéric Aurade, Aurélien De Reynies, Vincent Contremoulins, Frédéric Relaix, Orestis Faklaris, James Briscoe, Pascale Gilardi-Hebenstreit, Vanessa Ribes
Publikováno v:
PLoS Genetics, Vol 16, Iss 11, p e1009164 (2020)
The chromosome translocations generating PAX3-FOXO1 and PAX7-FOXO1 chimeric proteins are the primary hallmarks of the paediatric fusion-positive alveolar subtype of Rhabdomyosarcoma (FP-RMS). Despite the ability of these transcription factors to remo
Externí odkaz:
https://doaj.org/article/a5a0dd5b42044ce29ccf86fe6c876275
Autor:
Thibault Lagache, Alexandre Grassart, Stéphane Dallongeville, Orestis Faklaris, Nathalie Sauvonnet, Alexandre Dufour, Lydia Danglot, Jean-Christophe Olivo-Marin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Elucidating molecular organisation requires precise localisation and analysis. Here the authors develop SODA software for automatic and quantitative mapping of statistically coupled molecules, and use it to unravel spatial organisation of thousands o
Externí odkaz:
https://doaj.org/article/c72243110cc94c5f96e08005bd345ee6
Autor:
Nicolas Tissot, Jean-Antoine Lepesant, Fred Bernard, Kevin Legent, Floris Bosveld, Charlotte Martin, Orestis Faklaris, Yohanns Bellaïche, Maïté Coppey, Antoine Guichet
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Asymmetric nuclear positioning in the fruit fly oocyte is essential for the correct localization of axis determinants. Here, the authors show that different microtubule-dependent mechanisms contribute to nuclear transport and ensure the robustness of
Externí odkaz:
https://doaj.org/article/683345e7bb684599bdb1e55487e37dec
Autor:
Thierry Durroux, Jurriaan M. Zwier, Eric Trinquet, Orestis Faklaris, Martin Cottet, Jean-Philippe Pin
Publikováno v:
Pharmaceuticals, Vol 4, Iss 1, Pp 202-214 (2011)
The identification of new drugs exhibiting reduced adverse side-effects constitutes a great challenge for the next decade. Various steps are needed to screen for good ligand candidates and one of them is the evaluation of their binding properties. Ne
Externí odkaz:
https://doaj.org/article/ae64c31ca6164ee9b727fd83d074ad66
Autor:
Anthony Vial, Luca Costa, Patrice Dosset, Pietro Rosso, Gaëlle Boutières, Orestis Faklaris, Heiko Haschke, Pierre-Emmanuel Milhiet, Christine M. Doucet
Publikováno v:
Nanoscale. 15:5756-5770
Correlated fluorescence super-resolution and atomic force microscopy reveal the multiple conformations of human nuclear pore baskets.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9782c51c2b0a44b29dcb603d215b0c3d
https://doi.org/10.1039/d2nr06034e
https://doi.org/10.1039/d2nr06034e
Autor:
Maximiliaan Huisman, James J. Chambers, Alex Laude, Peter Bajcsy, Ulrike Boehm, Caterina Strambio-De-Castillia, Damir Sudar, Orestis Faklaris, Glyn Nelson, Mathias Hammer, Nathalie Gaudreault, Farzin Farzam, Carlas Smith, Claire M. Brown, Roland Nitschke, Alexander D. Corbett, Judith Lacoste, Jaime A. Pimentel, Alison J. North, Alessandro Rigano, David Grunwald
Publikováno v:
Nat Methods
1 -ABSTRACTDigital light microscopy provides powerful tools for quantitatively probing the real-time dynamics of subcellular structures. While the power of modern microscopy techniques is undeniable, rigorous record-keeping and quality control are re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbd113a5e98e72700c29cfdfd4a75ba
https://doi.org/10.1038/s41592-021-01327-9
https://doi.org/10.1038/s41592-021-01327-9
Autor:
Anthony Vial, Luca Costa, Patrice Dosset, Pietro Rosso, Gaëlle Boutières, Orestis Faklaris, Heiko Haschke, Pierre-Emmanuel Milhiet, Christine M. Doucet
Nuclear pore complexes (NPCs) are the only gateways between the nucleus and cytoplasm in eukaryotic cells. They restrict free diffusion to molecules below 5 nm while facilitating the active transport of selected cargoes, sometimes as large as the por
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd187d42d1df21ba141e94538fe6424
https://hal.science/hal-03871502/document
https://hal.science/hal-03871502/document
Autor:
Orestis Faklaris, Leslie Bancel-Vallée, Aurélien Dauphin, Baptiste Monterroso, Perrine Frère, David Geny, Tudor Manoliu, Sylvain de Rossi, Fabrice P. Cordelières, Damien Schapman, Roland Nitschke, Julien Cau, Thomas Guilbert
Publikováno v:
Journal of Cell Biology. 221
Although there is a need to demonstrate reproducibility in light microscopy acquisitions, the lack of standardized guidelines monitoring microscope health status over time has so far impaired the widespread use of quality control (QC) measurements. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47159226a14c82a6b9f2268c57b0caa3
https://doi.org/10.1083/jcb.202107093
https://doi.org/10.1083/jcb.202107093