Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Orestes Foresto-Neto"'
Autor:
Orestes Foresto-Neto, Ana Ruth Paolinetti Alves da Silva, Marcella Cipelli, Fernanda Paula Roncon Santana-Novelli, Niels Olsen Saraiva Camara
Publikováno v:
Kidney Research and Clinical Practice, Vol 42, Iss 5, Pp 561-578 (2023)
Kidneys are sensitive to disturbances in oxygen homeostasis. Hypoxia and activation of the hypoxia-inducible factor (HIF) pathway alter the expression of genes involved in the metabolism of renal and immune cells, interfering with their functioning.
Externí odkaz:
https://doaj.org/article/59f02d5eb6194696ab9350b200074fb9
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/5bf759e690094dd798fbb9cfbbf2e4a7
Autor:
Rodrigo Barbosa de Souza, Renan Barbosa Lemes, Orestes Foresto-Neto, Luara Lucena Cassiano, Dieter P Reinhardt, Keith M Meek, Ivan Hong Jun Koh, Philip N Lewis, Lygia V Pereira
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285418 (2023)
Fibrillin-1 is a pivotal structural component of the kidney's glomerulus and peritubular tissue. Mutations in the fibrillin-1 gene result in Marfan syndrome (MFS), an autosomal dominant disease of the connective tissue. Although the kidney is not con
Externí odkaz:
https://doaj.org/article/9b61dbdc740445ba97f4a1ca1dc341ef
Autor:
Amanda Helen Albino, Fernanda Florencia Fregnan Zambom, Orestes Foresto-Neto, Karin Carneiro Oliveira, Victor Ferreira Ávila, Simone Costa Alarcon Arias, Antonio Carlos Seguro, Denise Maria Avancini Costa Malheiros, Niels Olsen Saraiva Camara, Clarice Kazue Fujihara, Roberto Zatz
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Subjects recovering from acute kidney injury (AKI) are at risk of developing chronic kidney disease (CKD). The mechanisms underlying this transition are unclear and may involve sustained activation of renal innate immunity, with resulting renal infla
Externí odkaz:
https://doaj.org/article/e70aa310fc7a4cc89eb0342615a60cf4
Autor:
Ingrid Kazue Mizuno Watanabe, Magaiver Andrade-Silva, Orestes Foresto-Neto, Raphael José Ferreira Felizardo, Marco Aurélio Costa Matheus, Reinaldo Correa Silva, Marcos Antônio Cenedeze, Tâmisa Seeko Bandeira Honda, Luiz Augusto Buoro Perandini, Rildo Aparecido Volpini, Alvaro Pacheco-Silva, Niels Olsen Saraiva Câmara
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Increasing evidence shows the essential participation of gut microbiota in human health and diseases by shaping local and systemic immunity. Despite an accumulating body of studies showing that chronic kidney disease (CKD) is closely associated with
Externí odkaz:
https://doaj.org/article/db516efbd61a46d08a15fd735ac81ec2
Autor:
Orestes Foresto-Neto, Amanda Helen Albino, Simone Costa Alarcon Arias, Viviane Dias Faustino, Fernanda Florencia Fregnan Zambom, Marcos Antonio Cenedeze, Rosilene Motta Elias, Denise Maria Avancini Costa Malheiros, Niels Olsen Saraiva Camara, Clarice Kazue Fujihara, Roberto Zatz
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
High glucose concentration can activate TLR4 and NF-κB, triggering the production of proinflammatory mediators. We investigated whether the NF-κB pathway is involved in the pathogenesis and progression of experimental diabetic kidney disease (DKD)
Externí odkaz:
https://doaj.org/article/b6f26670264f4f4abaef66d9050fb5db
Autor:
Vinicius Andrade-Oliveira, Orestes Foresto-Neto, Ingrid Kazue Mizuno Watanabe, Roberto Zatz, Niels Olsen Saraiva Câmara
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Inflammation, a process intimately linked to renal disease, can be defined as a complex network of interactions between renal parenchymal cells and resident immune cells, such as macrophages and dendritic cells, coupled with recruitment of circulatin
Externí odkaz:
https://doaj.org/article/f486e94f65f84f7db75ddaada813eda6
Autor:
Orestes Foresto-Neto, Daniel R. Turin, Heather L. Holmes, Carmen J. Reynolds, Mariah L. Arneson, Pablo Cabrero, Muthuvel Jayachandran, Julian A.T. Dow, John C. Lieske, Eva Furrow, Michael F. Romero
Publikováno v:
Physiology. 38
Anoctamins (ANO) are activated by intracellular Ca2+ and function as phospholipid scramblases and/or Cl- channels. ANO4 is mutated in miniature schnauzers with calcium oxalate stones (CaOx), and ANO4 protein in urinary extracellular vesicles is decre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f84a642453bc3e8095dc190fce13ece0
https://doi.org/10.1152/physiol.2023.38.s1.5731663
https://doi.org/10.1152/physiol.2023.38.s1.5731663
Autor:
Barbara Bruna Abreu Castro, Helady Sanders-Pinheiro, Niels Olsen Saraiva-Camara, Orestes Foresto-Neto
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 48:1579-1588
In recent decades, there has been a progressive increase in the prevalence of obesity and chronic kidney disease. Renal lipotoxicity has been associated with obesity. Although lipids play fundamental physiological roles, the accumulation of lipids in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579adbd81ac474fc45f68a58851e144a
https://doi.org/10.1111/1440-1681.13556
https://doi.org/10.1111/1440-1681.13556
Publikováno v:
Kidney360
Seminal works have now revealed the gut microbiota is connected with several diseases, including renal disorders. The balance between optimal and dysregulated host-microbiota interactions has completely changed our understanding of immunity and infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e98f54073a69f2eb27f9311301841f
https://doi.org/10.34067/kid.0000292021
https://doi.org/10.34067/kid.0000292021