Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Oresta Makaruha Stegić"'
Autor:
Jasna Padovan, Linda Tomaskovic, Stribor Markovic, Milan Mesic, Hana Čipčić Paljetak, Mladen Mercep, Ines Glojnarić, Mihailo Banjanac, Barbara Stanić, Jovica Ralić, Vesna Munić, Oresta Makaruha Stegić, Marijana Komac, Vesna Eraković Haber, Boska Hrvacic
new concept in design of safe glucocorticoid therapy was introduced by conjugating potent glucocorticoid steroids with macrolides (macrolactonolides). These compounds were synthesized from various steroid 17β-carboxylic acids and 9a-N-(3-aminoalkyl)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef738a49ddc32a931c0b944f69099b06
https://www.zora.uzh.ch/id/eprint/76109/
https://www.zora.uzh.ch/id/eprint/76109/
Modeling Cellular Pharmacokinetics of 14- and 15-membered Macrolides with Physicochemical Properties
Autor:
Višnja Stepanić, Goran Kragol, Selvira Zulfikari, Mario Hlevnjak, Vesna Munić, Sanja Koštrun, Irena Ćaleta, Klára Valkó, Branka Tavčar, Oresta Makaruha-Stegić, Lara Mikac, Marko Dukši, Jovica Ralić, Iva Tatić, Kristina Butković, Ivica Malnar
Macrolides with 14- and 15-membered ring are characterized by high and extensive tissue distribution, as well as good cellular accumulation and retention. Since macrolide structures do not fit the Lipinski rule of five, macrolide pharmacokinetic prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecfa7ae4e0c0750281d380f8fbd31888
https://doi.org/10.1021/jm101317f
https://doi.org/10.1021/jm101317f