Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Orest Kuzyk"'
Autor:
Alessandra Riva, Orest Kuzyk, Erica Forsberg, Gary Siuzdak, Carina Pfann, Craig Herbold, Holger Daims, Alexander Loy, Benedikt Warth, David Berry
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Here, employing laser capture microdissection and omics, the authors determine the effects of fiber-deprived diet on the spatial structure of the murine colon microbiome, finding that the absence of dietary fiber and polysaccharides leads to local ch
Externí odkaz:
https://doaj.org/article/70178dfc05084f05adfe981c845fca81
Autor:
Christoph Gasche, Nicole Meisner-Kober, Guglielmo Roma, Martin Beibel, Vineeta Khare, Pavel Kovarik, Orest Kuzyk, Alexander Loy, Kyle Dammann, Rayko Evstatiev, Vitaly Sedlyarov, Florian Ebner, Sabin Bhuju, Ildiko Mesteri, Katharina Passecker, David Berry, Michaela Lang
CD8+ cytotoxic T-lymphocytes, NKp46+ natural killer cells and F4/80+ macrophages in tumors of AOM/DSS and APCMin mice. Analysis of cytokines secreted by small intestinal organoids upon MS-444 treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62bd3e10c0ddc740c6690074712f13d5
https://doi.org/10.1158/0008-5472.22410987
https://doi.org/10.1158/0008-5472.22410987
Autor:
Christoph Gasche, Nicole Meisner-Kober, Guglielmo Roma, Martin Beibel, Vineeta Khare, Pavel Kovarik, Orest Kuzyk, Alexander Loy, Kyle Dammann, Rayko Evstatiev, Vitaly Sedlyarov, Florian Ebner, Sabin Bhuju, Ildiko Mesteri, Katharina Passecker, David Berry, Michaela Lang
MS-444 restores splenic lymphoid follicles and decreases spleen weight in APCMin mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1cb82193dbe6290cc92bce2f297300
https://doi.org/10.1158/0008-5472.22410984
https://doi.org/10.1158/0008-5472.22410984
Autor:
Christoph Gasche, Nicole Meisner-Kober, Guglielmo Roma, Martin Beibel, Vineeta Khare, Pavel Kovarik, Orest Kuzyk, Alexander Loy, Kyle Dammann, Rayko Evstatiev, Vitaly Sedlyarov, Florian Ebner, Sabin Bhuju, Ildiko Mesteri, Katharina Passecker, David Berry, Michaela Lang
HuR is an RNA-binding protein implicated in immune homeostasis and various cancers, including colorectal cancer. HuR binding to AU-rich elements within the 3′ untranslated region of mRNAs encoding oncogenes, growth factors, and various cytokines le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c298f217fbe792ebb9434787d0395c6
https://doi.org/10.1158/0008-5472.c.6508122
https://doi.org/10.1158/0008-5472.c.6508122
Autor:
Christoph Gasche, Nicole Meisner-Kober, Guglielmo Roma, Martin Beibel, Vineeta Khare, Pavel Kovarik, Orest Kuzyk, Alexander Loy, Kyle Dammann, Rayko Evstatiev, Vitaly Sedlyarov, Florian Ebner, Sabin Bhuju, Ildiko Mesteri, Katharina Passecker, David Berry, Michaela Lang
Alpha diversity in feces of AOM/DSS and APCMin upon MS-444 treatment and indicator OTUs in AOM/DSS mouse feces.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833d817d5a438ee68d29e1ddb93d8af1
https://doi.org/10.1158/0008-5472.22410981.v1
https://doi.org/10.1158/0008-5472.22410981.v1
Autor:
Christoph Gasche, Nicole Meisner-Kober, Guglielmo Roma, Martin Beibel, Vineeta Khare, Pavel Kovarik, Orest Kuzyk, Alexander Loy, Kyle Dammann, Rayko Evstatiev, Vitaly Sedlyarov, Florian Ebner, Sabin Bhuju, Ildiko Mesteri, Katharina Passecker, David Berry, Michaela Lang
Weight curves of AOM/DSS and APCMin mice, DSS water consummtion and large bowel tumorigenesis in APCMin mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2430d8cfc69211aafe46528d2ab0077e
https://doi.org/10.1158/0008-5472.22410999
https://doi.org/10.1158/0008-5472.22410999
Autor:
Christoph Gasche, Nicole Meisner-Kober, Guglielmo Roma, Martin Beibel, Vineeta Khare, Pavel Kovarik, Orest Kuzyk, Alexander Loy, Kyle Dammann, Rayko Evstatiev, Vitaly Sedlyarov, Florian Ebner, Sabin Bhuju, Ildiko Mesteri, Katharina Passecker, David Berry, Michaela Lang
HuR nucleocytoplasmic shuttling is increased with increasing MS-444 concentrationsin an acute colitis model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153b770f193c989b918f66fd2a987f91
https://doi.org/10.1158/0008-5472.22410993
https://doi.org/10.1158/0008-5472.22410993
Autor:
Christoph Gasche, Nicole Meisner-Kober, Guglielmo Roma, Martin Beibel, Vineeta Khare, Pavel Kovarik, Orest Kuzyk, Alexander Loy, Kyle Dammann, Rayko Evstatiev, Vitaly Sedlyarov, Florian Ebner, Sabin Bhuju, Ildiko Mesteri, Katharina Passecker, David Berry, Michaela Lang
CRISPR/Cas9 HuR ko in RAW 264.7 macrophage cells confirmed by Sanger sequencing and Western blot analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf80a83468b95f9378643537deeea11
https://doi.org/10.1158/0008-5472.22410990.v1
https://doi.org/10.1158/0008-5472.22410990.v1
Autor:
Christoph Gasche, Nicole Meisner-Kober, Guglielmo Roma, Martin Beibel, Vineeta Khare, Pavel Kovarik, Orest Kuzyk, Alexander Loy, Kyle Dammann, Rayko Evstatiev, Vitaly Sedlyarov, Florian Ebner, Sabin Bhuju, Ildiko Mesteri, Katharina Passecker, David Berry, Michaela Lang
Crypt-villus length and HuR subcellular distribution as analyzed by immunohistochemistry and Western blot of nuclear and cytoplasmic fractions from isolated tumors in MS-444 treated and control mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa7f502970976c654a7621ac6dbfeda
https://doi.org/10.1158/0008-5472.22410996
https://doi.org/10.1158/0008-5472.22410996
Autor:
Christoph Gasche, Nicole Meisner-Kober, Guglielmo Roma, Martin Beibel, Vineeta Khare, Pavel Kovarik, Orest Kuzyk, Alexander Loy, Kyle Dammann, Rayko Evstatiev, Vitaly Sedlyarov, Florian Ebner, Sabin Bhuju, Ildiko Mesteri, Katharina Passecker, David Berry, Michaela Lang
Additional information on mouse experiments, colonoscopy, histology, immunohistochemical analysis and amplicon sequencing for microbiota analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eac164495355e49092910a4cbd38aed
https://doi.org/10.1158/0008-5472.22410975.v1
https://doi.org/10.1158/0008-5472.22410975.v1