Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Oren M. Becker"'
Autor:
Ofra Tirosh-Becker, Oren M. Becker
Publikováno v:
Journal of Jewish Languages. 10:24-53
The Tagged Algerian Judeo-Arabic (TAJA) corpus is the first linguistically annotated corpus of any Judeo-Arabic dialect regardless of geography and period. The corpus is a genre-diverse collection of written Modern Algerian Judeo-Arabic texts, encomp
Autor:
Alex Aizikovich, Alexander Konson, Nili Schutz, Alina Shitrit, Avihai Yacovan, Sima Mirilashvili, Rachel Ozeri, Daniel Sherman, Osnat Bohana-Kashtan, Oren M. Becker, Tzofit Kehat, Vered Behar, Efrat Ben-Zeev
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:6460-6468
Cancer cells preferentially use glycolysis rather than oxidative phosphorylation for their rapid growth. They consume large amount of glucose to produce lactate even when oxygen is abundant, a phenomenon known as the Warburg effect. This metabolic ch
Autor:
Oren M. Becker
Publikováno v:
Antitargets
Autor:
Yael Marantz, Alexander Heifetz, Dora Warshaviak, Silvia Noiman, Boaz Inbal, Maya Topf, Merav Fichman, Oren M. Becker, Zvi Naor, Noa Avisar, Sharon Shacham, Ori Kalid, Shay Bar-Haim
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 57:51-86
G-protein coupled receptors (GPCRs) are a major group of drug targets for which only one x-ray structure is known (the nondrugable rhodopsin), limiting the application of structure-based drug discovery to GPCRs. In this paper we present the details o
Publikováno v:
Proceedings of the National Academy of Sciences. 98:2188-2193
The effect of a solvation on the thermodynamics and kinetics of polyalanine (Ala 12 ) is explored on the basis of its energy landscapes in vacuum and in an aqueous solution. Both energy landscapes are characterized by two basins, one associated with
Autor:
Oren M. Becker, Michal Bachar
Publikováno v:
The Journal of Chemical Physics. 111:8672-8685
Melittin, a small peptide found in bee venom, is known to induce membrane lysis. A molecular dynamics simulation of melittin embedded in a hydrated dipalmitoylphosphatidylcholine bilayer is analyzed in order to study the peptide’s effect on water m
Autor:
Martin Karplus, Oren M. Becker
Publikováno v:
The Journal of Chemical Physics. 106:1495-1517
Topological characteristics of multidimensional potential energy surfaces are explored and the full conformation space is mapped on the set of local minima. This map partitions conformation space into energy-dependent or temperature-dependent “attr
Publikováno v:
The Journal of Chemical Physics. 103:3112-3123
Temperature quench echoes are analyzed in terms of the temperature–temperature correlation function in the harmonic approximation, and the resulting expressions are compared with molecular dynamics simulations. The relationship between the time dep
Autor:
Oren M. Becker
Publikováno v:
The Journal of Chemical Physics. 96:5488-5496
The theory of island formation in chemisorption [Becker and Ben‐Shaul, Phys. Rev. Lett. 61, 2859 (1988)], which treats chemisorption as a combination of direct adsorption and cluster formation, is generalized to account for the effects of cluster
Autor:
Oren M. Becker, Merav Fichman, Alexander Heifetz, Chen Dongli, Michael Kauffman, Dhanoa Dale S, Yael Marantz, Srinivasa Rao Cheruku, Sharon Shacham, Raphael Nudelman, Silvia Noiman, Anurag Sharadendu, Pradyumna Mohanty
Publikováno v:
Journal of medicinal chemistry. 49(11)
We report the discovery of a novel, potent, and selective amidosulfonamide nonazapirone 5-HT1A agonist for the treatment of anxiety and depression, which is now in Phase III clinical trials for generalized anxiety disorder (GAD). The discovery of 20m