Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Oren Barboy"'
Publikováno v:
Cancer Discovery. :OF1-OF10
Chimeric antigen receptor (CAR) T therapies hold immense promise to revolutionize cancer treatment. Nevertheless, key challenges, primarily in solid tumor settings, continue to hinder the application of this technology. Understanding CAR T-cell mecha
Autor:
Bjørt K. Kragesteen, Amir Giladi, Eyal David, Shahar Halevi, Laufey Geirsdóttir, Olga M. Lempke, Baoguo Li, Andreas M. Bapst, Ken Xie, Yonatan Katzenelenbogen, Sophie L. Dahl, Fadi Sheban, Anna Gurevich-Shapiro, Mor Zada, Truong San Phan, Roberto Avellino, Shuang-Yin Wang, Oren Barboy, Shir Shlomi-Loubaton, Sandra Winning, Philipp P. Markwerth, Snir Dekalo, Hadas Keren-Shaul, Merav Kedmi, Martin Sikora, Joachim Fandrey, Thorfinn S. Korneliussen, Josef T. Prchal, Barak Rosenzweig, Vladimir Yutkin, Fernando Racimo, Eske Willerslev, Chamutal Gur, Roland H. Wenger, Ido Amit
Publikováno v:
Nature Medicine. 29:1191-1200
Autor:
Merav Cohen, Amir Giladi, Oren Barboy, Pauline Hamon, Baoguo Li, Mor Zada, Anna Gurevich-Shapiro, Cristian Gabriel Beccaria, Eyal David, Barbara B. Maier, Mark Buckup, Iris Kamer, Aleksandra Deczkowska, Jessica Le Berichel, Jair Bar, Matteo Iannacone, Amos Tanay, Miriam Merad, Ido Amit
Publikováno v:
Nature Cancer
Nature Cancer, 2022, 3 (3), pp.303-317. ⟨10.1038/s43018-022-00338-5⟩
Nature Cancer, 2022, 3 (3), pp.303-317. ⟨10.1038/s43018-022-00338-5⟩
Comment in: DePICting T cell-APC crosstalk in cancer. Zhang T, Dong C. Nat Cancer. 2022 Mar;3(3):265-267. doi: 10.1038/s43018-022-00345-6. PMID: 35352059 No abstract available.; International audience; Despite their key regulatory role and therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb531288175fdd091b68b5f57f25bd1
https://hal-pasteur.archives-ouvertes.fr/pasteur-03866082
https://hal-pasteur.archives-ouvertes.fr/pasteur-03866082
Autor:
Ido Yofe, Tomer Landsberger, Adam Yalin, Isabelle Solomon, Cristobal Costoya, Dafne Franz Demane, Mansi Shah, Eyal David, Chamutal Borenstein, Oren Barboy, Ignacio Matos, Karl S. Peggs, Sergio A. Quezada, Ido Amit
Publikováno v:
Nature cancer. 3(11)
Despite the clinical success of checkpoint inhibitors, a substantial gap still exists in our understanding of their mechanism of action. While antibodies to cytotoxic T lymphocyte-associated protein-4 (CTLA-4) were developed to block inhibitory signa
Autor:
Ido Yofe, Tomer Landsberger, Adam Yalin, Isabelle Solomon, Cristobal Costoya, Dafne Franz Demane, Mansi Shah, Eyal David, Chamutal Borenstein, Oren Barboy, Ignacio Matos, Karl S. Peggs, Sergio A. Quezada, Ido Amit
Publikováno v:
Nature Cancer. 3:1404-1404
Autor:
Ido Yofe, Shir Shlomi-Loubaton, Yana Davidov, Oranit Cohen-Ezra, Oren Barboy, Diego Jaitin, David Goitein, Dominik Pfister, Aleksandra Deczkowska, Amir Giladi, Merav Cohen, Chamutal Gur, Mathias Heikenwalder, Michael Safran, Susanne Roth, Sandrine Henri, Assaf Weiner, Eylon Lahat, Ziv Ben-Ari, Gil Ben Yakov, Bernard Malissen, Mengjie Qiu, Ido Amit, Shing Kam, Hila Hermon, Yousuf Suhail, Mariya Likhter, Achim Weber, Eran Elinav, Eyal David, Pierluigi Ramadori
Publikováno v:
Nature Medicine
Nature Medicine, Nature Publishing Group, 2021, ⟨10.1038/s41591-021-01344-3⟩
Nature Medicine, 2021, ⟨10.1038/s41591-021-01344-3⟩
Nature Medicine, Nature Publishing Group, 2021, ⟨10.1038/s41591-021-01344-3⟩
Nature Medicine, 2021, ⟨10.1038/s41591-021-01344-3⟩
International audience; Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are prevalent liver conditions that underlie the development of life-threatening cirrhosis, liver failure and liver cancer. Chronic necro-infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a635b1f210791c3fa08beb091c7565
https://hal.archives-ouvertes.fr/hal-03234079
https://hal.archives-ouvertes.fr/hal-03234079
Autor:
Merav, Cohen, Amir, Giladi, Oren, Barboy, Pauline, Hamon, Baoguo, Li, Mor, Zada, Anna, Gurevich-Shapiro, Cristian Gabriel, Beccaria, Eyal, David, Barbara B, Maier, Mark, Buckup, Iris, Kamer, Aleksandra, Deczkowska, Jessica, Le Berichel, Jair, Bar, Matteo, Iannacone, Amos, Tanay, Miriam, Merad, Ido, Amit
Publikováno v:
Nature cancer. 3(3)
Despite their key regulatory role and therapeutic potency, the molecular signatures of interactions between T cells and antigen-presenting myeloid cells within the tumor microenvironment remain poorly characterized. Here, we systematically characteri
Autor:
Aleksandra, Deczkowska, Eyal, David, Pierluigi, Ramadori, Dominik, Pfister, Michal, Safran, Baoguo, Li, Amir, Giladi, Diego Adhemar, Jaitin, Oren, Barboy, Merav, Cohen, Ido, Yofe, Chamutal, Gur, Shir, Shlomi-Loubaton, Sandrine, Henri, Yousuf, Suhail, Mengjie, Qiu, Shing, Kam, Hila, Hermon, Eylon, Lahat, Gil, Ben Yakov, Oranit, Cohen-Ezra, Yana, Davidov, Mariya, Likhter, David, Goitein, Susanne, Roth, Achim, Weber, Bernard, Malissen, Assaf, Weiner, Ziv, Ben-Ari, Mathias, Heikenwälder, Eran, Elinav, Ido, Amit
Publikováno v:
Nature medicine. 27(6)
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are prevalent liver conditions that underlie the development of life-threatening cirrhosis, liver failure and liver cancer. Chronic necro-inflammation is a critical fa
Autor:
Miriam Merad, Merav Cohen, Jessica Le Berichel, Myron Schwartz, Nausicaa Malissen, Joel Kim, Amir Giladi, Steven Hamel, Eyal David, Assaf Magen, Alexandra Tabachnikova, Mark Buckup, Fiona Desland, Ephraim Kenigsberg, Leanna Troncoso, Pauline Hamon, Oren Barboy, Thomas U. Marron, Ido Amit, Zhen Zhao, Christie Chang
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A713-A713
BackgroundHepatocellular carcinoma (HCC) has a dismal prognosis, and though checkpoint blocking antibodies have significantly improved patient outcome, many patients remain left out, highlighting the need to identify additional immune target to enhan
Autor:
Chamutal Gur, Shuang-Yin Wang, Fadi Sheban, Mor Zada, Baoguo Li, Fadi Kharouf, Hagit Peleg, Suhail Aamar, Adam Yalin, Daniel Kirschenbaum, Yolanda Braun-Moscovici, Diego Adhemar Jaitin, Tomer meir-salame, Efrat Hagai, Bjørt K. Kragesteen, Batia Avni, Sigal Grisariu, Chamutal Bornstein, Shir Shlomi-Loubaton, Eyal David, Rony Shreberk-Hassidim, Vered Molho-Pessach, Dalit Amar, Tomer Tzur, Rottem Kuint, Moshe Gross, Oren Barboy, Adi Moshe, Liat Fellus-Alyagor, Dana Hirsch, Yoseph Addadi, Shlomit Erenfeld, Moshe Biton, Tehila Tzemach, Anat Elazary, Yaakov Naparstek, Reut Tzemach, Assaf Weiner, Amir Giladi, Alexandra Balbir-Gurman, Ido Amit
Publikováno v:
Cell
Systemic sclerosis (scleroderma, SSc) is an incurable autoimmune disease with high morbidity and mortality rates. Here, we conducted a population-scale single-cell genomic analysis of skin and blood samples of 56 healthy controls and 97 SSc patients