Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation.

Autor: Clausen AR; Genome Integrity &Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institute of Health (NIH), Research Triangle Park, North Carolina, USA., Lujan SA; Genome Integrity &Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institute of Health (NIH), Research Triangle Park, North Carolina, USA., Burkholder AB; Integrative Bioinformatics, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA., Orebaugh CD; Genome Integrity &Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institute of Health (NIH), Research Triangle Park, North Carolina, USA., Williams JS; Genome Integrity &Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institute of Health (NIH), Research Triangle Park, North Carolina, USA., Clausen MF; Department of Genetics, High Throughput Sequencing Facility, University of North Carolina, Chapel Hill, North Carolina, USA., Malc EP; Department of Genetics, High Throughput Sequencing Facility, University of North Carolina, Chapel Hill, North Carolina, USA., Mieczkowski PA; Department of Genetics, High Throughput Sequencing Facility, University of North Carolina, Chapel Hill, North Carolina, USA., Fargo DC; Integrative Bioinformatics, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA., Smith DJ; Center for Genomics and Systems Biology, Department of Biology, New York University, New York, New York, USA., Kunkel TA; Genome Integrity &Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institute of Health (NIH), Research Triangle Park, North Carolina, USA.

Publikováno v: Nature structural & molecular biology [Nat Struct Mol Biol] 2015 Mar; Vol. 22 (3), pp. 185-91. Date of Electronic Publication: 2015 Jan 26.

The TREX1 C-terminal region controls cellular localization through ubiquitination.

Autor: Orebaugh CD; From the Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157., Fye JM, Harvey S, Hollis T, Wilkinson JC, Perrino FW

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2013 Oct 04; Vol. 288 (40), pp. 28881-92. Date of Electronic Publication: 2013 Aug 26.

Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome.

Autor: Fye JM; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA., Orebaugh CD, Coffin SR, Hollis T, Perrino FW

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2011 Sep 16; Vol. 286 (37), pp. 32373-82. Date of Electronic Publication: 2011 Aug 01.