Isolation and characterization of neural crest-derived stem cells from dental pulp of neonatal mice.

Autor: Kajohnkiart Janebodin, Orapin V Horst, Nicholas Ieronimakis, Gayathri Balasundaram, Kanit Reesukumal, Busadee Pratumvinit, Morayma Reyes

Publikováno v: PLoS ONE, Vol 6, Iss 11, p e27526 (2011)

Dental pulp stem cells (DPSCs) are shown to reside within the tooth and play an important role in dentin regeneration. DPSCs were first isolated and characterized from human teeth and most studies have focused on using this adult stem cell for clinic

Externí odkaz: https://doaj.org/article/84b6a1403098409b81c0a61447c7ab86

Laser capture microdissection enables cellular and molecular studies of tooth root development

Autor: Orapin V. Horst, Martha J. Somerman, Jian Xun Sun, Roger E. Bumgarner, Bryce Lakely, Hai Zhang

Publikováno v: International Journal of Oral Science

Epithelial-mesenchymal interactions (EMIs) are critical for tooth development. Molecular mechanisms mediating these interactions in root formation is not well understood. Laser capture microdissection (LCM) and subsequent microarray analyses enable l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d40ab61f0c0fe74359735763d31d685
https://doi.org/10.1038/ijos.2012.15

WDR72 models of structure and function: a stage-specific regulator of enamel mineralization

Autor: D. Chandra, Li Zhu, K.A. Katsura, Thuan Le, Yaou Zhang, Orapin V. Horst, Pamela DenBesten, Michael H. Le, Jeremy A. Horst, Yukiko Nakano

Publikováno v: Matrix biology : journal of the International Society for Matrix Biology
Katsura, KA; Horst, JA; Chandra, D; Le, T; Nakano, Y; Zhang, Y; et al.(2013). WDR72 models of structure and function: A stage-specific regulator of enamel mineralization. Matrix Biology. doi: 10.1016/j.matbio.2014.06.005. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/8003v4qx

Amelogenesis Imperfecta (AI) is a clinical diagnosis that encompasses a group of genetic mutations, each affecting processes involved in tooth enamel formation and thus, result in various enamel defects. The hypomaturation enamel phenotype has been d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7513b61f8b3875c2fb9ae6a21f471804
https://escholarship.org/uc/item/8003v4qx

Fluorosed Mouse Ameloblasts Have Increased SATB1 Retention and Gαq Activity

Autor: Yan Zhang, Pamela K. Den Besten, Li Zhu, Ralf J. Radlanski, Sunita P. Ho, Yukiko Nakano, Jiyeon Kim, Orapin V. Horst

Publikováno v: PLoS ONE, Vol 9, Iss 8, p e103994 (2014)
PLoS ONE

Dental fluorosis is characterized by subsurface hypomineralization and increased porosity of enamel, associated with a delay in the removal of enamel matrix proteins. To investigate the effects of fluoride on ameloblasts, A/J mice were given 50 ppm s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14e0edd919640de8e303bc507960310
https://doi.org/10.17169/refubium-19335

Stem cell and biomaterials research in dental tissue engineering and regeneration

Autor: Ophir D. Klein, Orapin V. Horst, Tejal A. Desai, Miquella G. Chavez, Andrew H. Jheon

Publikováno v: Dental clinics of North America, vol 56, iss 3

The emergence of tissue engineering and regenerative medicine shed new light on the treatment of patients with degenerative disorders. These approaches combine tools from a variety of fields such as stem-cell biology, biomaterials, and developmental

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce120bd8123d5ddaced65840eda15bc
https://escholarship.org/uc/item/3bp6n5xj