Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Oranee Daniels"'
Autor:
Kathryn Kersey, Christina B. Campbell, K.H.S. Kim, Ross G. Vickery, Scott R. Armstrong, Julia L. McCullough, David Beattie, Oranee Daniels, Yu-Ping Li, Carrie Richardson, Pamela R. Tsuruda
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 2 (2011)
Frontiers in Pharmacology, Vol 2 (2011)
This study evaluated the in vitro and in vivo pharmacological properties of TD-8954, a potent and selective 5-HT4 receptor agonist. TD-8954 had high affinity (pKi = 9.4) for human recombinant 5-HT4(c) (h5-HT4(c)) receptors, and selectivity (> 2,000-f
Autor:
Minghan Wang, John M. Rossi, Maurice Emery, Edgar Bautista, Oranee Daniels, Riccardo Perfetti, Katherine Paweletz, Anna Akrami, Marc R. Gastonguay, Megan A. Gibbs, John P. Gibbs, Ian McCaffery, Brian H. Smith
Publikováno v:
Journal of clinical pharmacology. 51(6)
Inhibition of 11β-HSD1 is hypothesized to improve measures of insulin sensitivity and hepatic glucose output in patients with type II diabetes. AMG 221 is a potent, small molecule inhibitor of 11β-HSD1. The objective of this analysis is to describe
Publikováno v:
American Journal of Gastroenterology. 106:S513-S514