Zobrazeno 1 - 10
of 1 776
pro vyhledávání: '"Orally active"'
Autor:
Takanobu Nakajima, Maiko Shobako, Kentaro Kaneko, Atsushi Kurabayashi, Masaru Sato, Kousaku Ohinata
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 7, Pp 177-188 (2024)
Abstract Eggs not only contain all the molecules necessary to nurture new life but are also rich in nutrients such as high‐quality protein. For example, epidemiologic studies have shown that egg intake is positively correlated with cognitive functi
Externí odkaz:
https://doaj.org/article/6d8fca493c1546d3bac740feaed0997b
Akademický článek
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Publikováno v:
Pharmaceutical Fronts, Vol 04, Iss 01, Pp e22-e29 (2022)
Abstract In this study, the synthesis and biological evaluation of a variety of benzoheterocyclic-containing benzamide derivatives were described. Some of these compounds were proved to inhibiting the activity of histone deacetylase 1 (HDAC1) with IC
Externí odkaz:
https://doaj.org/article/652a7f8b7fe445a4a95d61be96e99bb0
Autor:
Yoshimasa Asada, Yoshiki Hashiba, Yukio Hattori, Daichi Inoue, Rie Ito, Noritaka Fukunaga, Megumi Sonohara
Publikováno v:
Reproductive Medicine and Biology, Vol 18, Iss 3, Pp 290-295 (2019)
Abstract Purpose The clinical utility of chlormadinone acetate tablets (Lutoral™), an orally active progestin which has been available since June 2007, was compared to an in‐house vaginal suppository formulation of progesterone used between 2006
Externí odkaz:
https://doaj.org/article/1a98013a1d9241aaa06f21b91faeab6c
Akademický článek
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Akademický článek
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Publikováno v:
Expert Opinion on Pharmacotherapy. 23:19-28
Introduction Anemia is one of the major complications of chronic kidney disease (CKD) and is associated with poor clinical outcomes. Erythropoiesis-stimulating agents (ESAs) have been the mainstay of renal anemia treatment. However, there are several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa3ba61f9fed189e3a0073172500c16
https://doi.org/10.1080/14656566.2021.1993821
https://doi.org/10.1080/14656566.2021.1993821
Publikováno v:
Clinical Obstetrics & Gynecology. 64:837-849
Gonadotropin-releasing hormone (GnRH) analogues have been used in clinical practice for nearly 3 decades. Beginning with GnRH agonists, these agents have been used to treat hormone-dependent disease and to suppress gonadotropin production in assisted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8c5021475a021e514ca159e3d91d61
https://doi.org/10.1097/grf.0000000000000664
https://doi.org/10.1097/grf.0000000000000664
Publikováno v:
Molecules, Vol 20, Iss 6, Pp 11046-11062 (2015)
Thrombotic disorders represent the major share of the various cardiovascular diseases, and significant progress has been made in the development of synthetic thrombin inhibitors as new anticoagulants. In addition to the development of highly potent a
Externí odkaz:
https://doaj.org/article/1c70f1844f3e46b2b7ec1238d96d7318
Autor:
Qian He, Jing-Rui Chai, Liming Shao, Yujun Wang, Zixiang Li, Yuan-Yuan Wei, Zhuibai Qiu, Rongrong Ye, Wei Li, Wei Fu, Linqian Yu, Xiao Liu, Jing-Gen Liu, Shuang Jiang, Qiong Xie, Linghui Kong
Publikováno v:
Journal of Medicinal Chemistry. 64:12414-12433
The search for selective kappa opioid receptor (κOR) agonists with an improved safety profile is an area of interest in opioid research. In this work, a series of m-substituted analogs were designed, synthesized, and assayed, resulting in the identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::782b113f193a9a9d39406c4ee485eb9c
https://doi.org/10.1021/acs.jmedchem.1c01082
https://doi.org/10.1021/acs.jmedchem.1c01082