Zobrazeno 1 - 10
of 468
pro vyhledávání: '"Oral formulation"'
Autor:
Varricchio A, Ciprandi G
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 5471-5477 (2024)
Attilio Varricchio,1 Giorgio Ciprandi,2 Study Group on respiratory infection management in clinical practice included:Francesco Paolo Brunese, Luigi Costanzo, Lorenzo Cresta, Maurizio Daccò, Donatella Del Gaizo, Carla Dominici, Cosimo Lanza, Michele
Externí odkaz:
https://doaj.org/article/7dfed8a5ac6c40c3bab546a86d029e83
Publikováno v:
Shipin gongye ke-ji, Vol 45, Iss 10, Pp 395-400 (2024)
Astaxanthin is a fat-soluble lutein carotenoid with good antioxidant, anti-inflammatory and immunomodulatory activities. However, its poor oral bioavailability lead to limited clinical application. Recently, in order to improve the bioavailability of
Externí odkaz:
https://doaj.org/article/253894a7513d4bcabe29de99c7388b37
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 886 (2024)
This study aimed to develop an effective oral formulation of semaglutide, a glucagon-like peptide-1 receptor agonist, using an organometallic phyllosilicate-based colonic delivery system. The core nanocomplex (AMP-Sema) of 3-aminopropyl-functionalize
Externí odkaz:
https://doaj.org/article/478dc4f4a03d44a6854097455217f81d
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractAmphotericin B (AmB) is regarded as a first-line therapy against life-threatening invasive fungal infections. Due to its poor oral bioavailability, AmB is restricted to intravenous administration in clinical practice. As science continues to
Externí odkaz:
https://doaj.org/article/ffcbbbb50a594155b7731a1f3df533eb
Autor:
Issraa Al-Obaidi, Anna K. Krome, Karl G. Wagner, Kenneth Pfarr, Annette C. Kuesel, Hannah K. Batchelor
Publikováno v:
Parasites & Vectors, Vol 15, Iss 1, Pp 1-22 (2022)
Abstract It is recognised that paediatric indications and age-appropriate formulations are required to ensure that paediatric populations receive appropriate pharmacotherapeutic treatment. The lack of information on dosing, efficacy and safety data (
Externí odkaz:
https://doaj.org/article/cb081ec4d0ac400c810988dfbaf38ade
Autor:
Muhammad Khurram Waqas, Shees Safdar, Manal Buabeid, Akram Ashames, Muhammad Akhtar, Ghulam Murtaza
Publikováno v:
Journal of Experimental Nanoscience, Vol 17, Iss 1, Pp 522-534 (2022)
Chitosan-based nano-sized particles increase the penetration of the drug through the narrow junction into the bloodstream and target the specific site. The objective of this study was to prepare chitosan nanoparticles to entrap a hydrophobic drug (ta
Externí odkaz:
https://doaj.org/article/a7566fce75234656ae66fe5abcd5c795
Autor:
Cristina Matteo, Isabella Orienti, Adriana Eramo, Ann Zeuner, Mariella Ferrari, Alice Passoni, Renzo Bagnati, Marianna Ponzo, Ezia Bello, Massimo Zucchetti, Roberta Frapolli
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 387 (2024)
We describe the development and validation of a HPLC-MS/MS method to assess the pharmacokinetics and tumor distribution of fenretinide, a synthetic retinoid chemically related to all-trans-retinoic acid, after administration of a novel oral nanoformu
Externí odkaz:
https://doaj.org/article/27825a3d5a704a958b9781168ea195db
Akademický článek
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Autor:
Celeste Manfredi, Lorenzo Spirito, Francesco Paolo Calace, Raffaele Balsamo, Marco Terribile, Marco Stizzo, Lorenzo Romano, Luigi Napolitano, Gianluigi Califano, Luigi Cirillo, Giovanni Maria Fusco, Claudia Rosati, Carmelo Quattrone, Carmine Sciorio, Massimiliano Creta, Nicola Longo, Marco De Sio, Davide Arcaniolo
Publikováno v:
Pathophysiology, Vol 29, Iss 3, Pp 365-373 (2022)
Intravesical chemotherapy may cause chemical cystitis and related lower urinary tract symptoms (LUTS). The aims of this study were to evaluate the efficacy and safety of an oral preparation of hyaluronic acid (HA), chondroitin sulfate (CS), curcumin,
Externí odkaz:
https://doaj.org/article/f74fb24f9d41488f9a3ac6557ac1d4cd
Autor:
Jaylen C. Mans, Xiaowei Dong
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2691 (2023)
Sorafenib (SFN) is an anticancer multi-kinase inhibitor with great therapeutic potential. However, SFN has low aqueous solubility, which limits its oral absorption. Lipids and surfactants have the potential to improve the solubility of water-insolubl
Externí odkaz:
https://doaj.org/article/c58bed6b9284458a924fdd3d75201720