Zobrazeno 1 - 10
of 2 242
pro vyhledávání: '"Oral Treatment"'
Autor:
Edward P. Feener, Rebecca L. Davie, Nivetha Murugesan, Stephen J. Pethen, Sally L. Hampton, Michael D. Smith, Paul K. Audhya, Chris M. Yea
Publikováno v:
Drugs and Drug Candidates, Vol 3, Iss 2, Pp 328-341 (2024)
Sebetralstat is a novel, potent, and selective oral plasma kallikrein inhibitor drug candidate in clinical development for the on-demand treatment of hereditary angioedema (HAE). Upon binding, sebetralstat induces a conformational change in the activ
Externí odkaz:
https://doaj.org/article/c898ea85087542009c61e6fcd2741b8b
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract This investigation addresses the challenge of suboptimal unnatural amino acid (UAA) utilization in the site‐specific suppression of nonsense mutations through genetic code expansion, which is crucial for protein restoration and precise pro
Externí odkaz:
https://doaj.org/article/90abd7c242664e328fc9fb7dc8e338e0
Autor:
Eligio Parente, Giulia Colannino, Gabriele Bilotta, Maria Salomé Bezerra Espinola, Sara Proietti, Mario Montanino Oliva, Isabella Neri, Cesare Aragona, Vittorio Unfer
Publikováno v:
Clinics and Practice, Vol 13, Iss 5, Pp 1123-1129 (2023)
Background—Pregnancy represents a nutritional challenge, since macro- and micronutrients intake can affect mother’ health and influence negative outcomes. The aim of this retrospective pilot study is to evidence whether the oral supplementation w
Externí odkaz:
https://doaj.org/article/85e7ab4ad45c4932a3c3e3da83f073fe
Publikováno v:
BMC Oral Health, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Sexual dimorphism is obvious not only in the overall architecture of human body, but also in intraoral details. Many studies have found a correlation between gender and morphometric features of teeth, such as mesio-distal diameter
Externí odkaz:
https://doaj.org/article/a15c447cad614223a366d06d1bd6cef5
Publikováno v:
Arthroplasty, Vol 5, Iss 1, Pp 1-7 (2023)
Abstract The antibiotic treatment of periprosthetic joint infections (PJI) is complicated by the presence of biofilm produced by bacteria on the abiotic surface of the implant. Bacteria within the deeper layers of the biofilm become metabolically les
Externí odkaz:
https://doaj.org/article/fb834154bccd4b4cbba4824f2306a89f
SWOT and Root Cause Analyses of Antimicrobial Resistance to Oral Antimicrobial Treatment of Cystitis
Publikováno v:
Antibiotics, Vol 13, Iss 4, p 328 (2024)
Nearly 150 million cases of urinary tract infections (UTIs) are reported each year, of which uncomplicated cystitis triggers > 25% of outpatient prescriptions of oral antimicrobial treatment (OAT). OAT aids immune cells infiltrating the urothelium in
Externí odkaz:
https://doaj.org/article/dddb42d0f54d470d8caa545980c889f6
Autor:
Mahamadou Bassirou Souleymane, Tom Decroo, Alphazazi Soumana, Ibrahim Maman Lawan, Assiatou Gagara-Issoufou, Souleymane Halidou-Moussa, Nimer Ortuño-Gutiérrez, Eric Adehossi, Saïdou Mamadou, Armand Van Deun, Alberto Piubello
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background Rifampicin-resistant tuberculosis (RR-TB) treatment requires combination treatment, which frequently causes serious adverse events and globally results in not much more than 60% treatment success. In Niger, a high cure rate was ob
Externí odkaz:
https://doaj.org/article/7a5ecc45907945e595f10525773246fc
Oral Antibiotics for Bacteremia and Infective Endocarditis: Current Evidence and Future Perspectives
Autor:
Gerasimos Eleftheriotis, Markos Marangos, Maria Lagadinou, Sanjay Bhagani, Stelios F. Assimakopoulos
Publikováno v:
Microorganisms, Vol 11, Iss 12, p 3004 (2023)
Bacteremia and endocarditis are two clinical syndromes that, for decades, were managed exclusively with parenteral antimicrobials, irrespective of a given patient’s clinical condition, causative pathogen, or its antibiotic susceptibility profile. T
Externí odkaz:
https://doaj.org/article/d4f1078ceda348cea7b09ae639f0cd34
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Autor:
Matthias A. Fante, Dennis C. Harrer, Barbara Zartner, Florian Lüke, Stephanie Mayer, Karin Menhart, Albrecht Reichle, Wolfgang Herr, Martin Vogelhuber, Daniel Heudobler
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposePeripheral T-cell lymphoma (PTCL) is a rare and heterogenous hematologic malignancy with poor prognosis especially in elderly and frail patients who are not eligible for intensive treatment. The resulting palliative setting necessitates tolera
Externí odkaz:
https://doaj.org/article/e088df970cad4128946c8c59a3664e32