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Cholinekinase alpha as an androgen receptor chaperone and prostate cancer therapeutic target

Autor: Asim, Mohammad, Massie, Charles E., Orafidiya, Folake, Pértega-Gomes, Nelma, Warren, Anne Y., Esmaeili, Mohsen, Selth, Luke A., Zecchini, Heather I., Luko, Katarina, Qureshi, Arham, Baridi, Ajoeb, Menon, Suraj, Madhu, Basetti, Escriu, Carlos, Lyons, Scott, Vowler, Sarah L., Zecchini, Vincent R., Shaw, Greg, Hessenkemper, Wiebke, Russell, Roslin, Mohammed, Hisham, Stefanos, Niki, Lynch, Andy G., Grigorenko, Elena, D’Santos, Clive, Taylor, Chris, Lamb, Alastair, Sriranjan, Rouchelle, Yang, Jiali, Stark, Rory, Dehm, Scott M., Rennie, Paul S., Carroll, Jason S., Griffiths, John R., Tavaré, Simon, Mills, Ian G., McEwan, Iain J., Baniahmad, Aria, Tilley, Wayne D., Neal, David E.

The RNA-seq data generated during this work has been submitted to Gene Expression Omnibus and is available for viewing at the following link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?token = ytazouoixxedjal&acc=GSE63700. Background: The androgen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______901::3a1f71ea0a4c63d5058780e750af3392
https://hdl.handle.net/10023/11481

Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target

Autor: Asim, Mohammad, Massie, Charles E, Orafidiya, Folake, Pértega-Gomes, Nelma, Warren, Anne Y, Esmaeili, Mohsen, Selth, Luke A, Zecchini, Heather I, Luko, Katarina, Qureshi, Arham, Baridi, Ajoeb, Menon, Suraj, Madhu, Basetti, Escriu, Carlos, Lyons, Scott, Vowler, Sarah L, Zecchini, Vincent R, Shaw, Greg, Hessenkemper, Wiebke, Russell, Roslin, Mohammed, Hisham, Stefanos, Niki, Lynch, Andy G, Grigorenko, Elena, D'Santos, Clive, Taylor, Chris, Lamb, Alastair, Sriranjan, Rouchelle, Yang, Jiali, Stark, Rory, Dehm, Scott M, Rennie, Paul S, Carroll, Jason S, Griffiths, John R, Tavaré, Simon, Mills, Ian G, McEwan, Iain J, Baniahmad, Aria, Tilley, Wayne D, Neal, David E

Publikováno v: JNCI Journal of the National Cancer Institute
Asim, M, Massie, C E, Orafidiya, F, Pértega-Gomes, N, Warren, A Y, Esmaeili, M, Selth, L A, Zecchini, H I, Luko, K, Qureshi, A, Baridi, A, Menon, S, Madhu, B, Escriu, C, Lyons, S, Vowler, S L, Zecchini, V R, Shaw, G, Hessenkemper, W, Russell, R, Mohammed, H, Stefanos, N, Lynch, A G, Grigorenko, E, D'Santos, C, Taylor, C, Lamb, A, Sriranjan, R, Yang, J, Stark, R, Dehm, S M, Rennie, P S, Carroll, J S, Griffiths, J R, Tavaré, S, Mills, I G, McEwan, I J, Baniahmad, A, Tilley, W D & Neal, D E 2016, ' Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target ', Journal of the National Cancer Institute, vol. 108, no. 5 . https://doi.org/10.1093/jnci/djv371

BACKGROUND: The androgen receptor (AR) is a major drug target in prostate cancer (PCa). We profiled the AR-regulated kinome to identify clinically relevant and druggable effectors of AR signaling.METHODS: Using genome-wide approaches, we interrogated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dfd079dddf0ec76bd511ce5978393444
http://europepmc.org/articles/PMC4849803

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