Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Ora Kofman"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionEnvironmental and genetic factors contribute to the increased risk for neurodevelopmental disorders, including deficits in the development of social communication. In the mouse, ultrasonic vocalizations emitted by the pup stimulate matern
Externí odkaz:
https://doaj.org/article/675cf58b02ba40a4904c26c0fdf50638
Autor:
Dmitry Frank, Benjamin F. Gruenbaum, Ilan Shelef, Vladislav Zvenigorodsky, Olena Severynovska, Ilya Fleidervish, Boris Knyazer, Amit Frenkel, Alexander Zlotnik, Ora Kofman, Matthew Boyko
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Traumatic brain injury (TBI) is a serious condition that is associated with an increased risk of severe, long-term psychiatric consequences. Drugs that target the glutamatergic system have proven successful in treating both TBI and many of i
Externí odkaz:
https://doaj.org/article/506aa32df8be40c4be84218f6fb61999
Autor:
Matthew Boyko, Benjamin F. Gruenbaum, Dmitry Frank, Dmitry Natanel, Shahar Negev, Abed N. Azab, Guy Barsky, Boris Knyazer, Ora Kofman, Alexander Zlotnik
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5897 (2023)
A healthy blood–brain barrier (BBB) shields the brain from high concentrations of blood glutamate, which can cause neurotoxicity and neurodegeneration. It is believed that traumatic brain injury (TBI) causes long-term BBB disruption, subsequently i
Externí odkaz:
https://doaj.org/article/321031faa31842ea852f9bc779ba86aa
Autor:
Dmitry Frank, Benjamin F. Gruenbaum, Ilan Shelef, Vladislav Zvenigorodsky, Olena Severynovska, Ron Gal, Michael Dubilet, Alexander Zlotnik, Ora Kofman, Matthew Boyko
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Depression is a common and serious complication following traumatic brain injury (TBI). Both depression and TBI have independently been associated with pathologically elevated extracellular brain glutamate levels. In the setting of TBI, blood glutama
Externí odkaz:
https://doaj.org/article/028b2f27bb6b4a10bddb39cb12e7bf01
Autor:
Itay Shekel, Shaked Giladi, Eynav Raykin, May Weiner, Vered Chalifa-Caspi, Dror Lederman, Ora Kofman, Hava M. Golan
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Studies in rodent models suggest that calls emitted by isolated pups serve as an early behavioral manifestation of communication deficits and autistic like behavior. Previous studies in our labs showed that gestational exposure to the pesticide chlor
Externí odkaz:
https://doaj.org/article/2eb0f174c9934c3ba3a1a53fc8fbc456
Publikováno v:
Behavioral and Brain Functions, Vol 15, Iss 1, Pp 1-9 (2019)
Abstract Background Signs of pervasive developmental disorder and social deficits were reported in toddlers and children whose mothers were exposed to organophosphate pesticides during pregnancy. Deficits in social preference were reported in adult m
Externí odkaz:
https://doaj.org/article/cd6e28cdbb01434b95669d2bf7c5e35b
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239738 (2020)
The levels and activity of the enzyme paraoxonase 1 affect the vulnerability to the teratogenic effects of organophosphate pesticides. Mutant mice lacking the gene for paraoxonase1 (PON1-/-) are more susceptible to the toxic effects of chlorpyrifos,
Externí odkaz:
https://doaj.org/article/d3df3ac3ee5d4da7b153e61c52d3c3f3
Publikováno v:
Environmental Health, Vol 16, Iss 1, Pp 1-10 (2017)
Abstract Background Children are at daily risk for exposure to organophosphate insecticides, of which the most common is chlorpyrifos (CPF). Exposure of pregnant women to CPF was linked to decreased birth weight, abnormal reflexes, reduction in IQ, a
Externí odkaz:
https://doaj.org/article/c7cad519a00f45569d383cacf8a0c66b
Autor:
Maya Rozenfeld, Ivana Savic Azoulay, Tsipi Ben Kasus Nissim, Alexandra Stavsky, Moran Melamed, Grace Stutzmann, Michal Hershfinkel, Ora Kofman, Israel Sekler
Publikováno v:
Cell Reports. 41:111772
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4ee7351f189475655ea3b964ffb387c
https://doi.org/10.1016/j.celrep.2022.111772
https://doi.org/10.1016/j.celrep.2022.111772
Autor:
Maya, Rozenfeld, Ivana Savic, Azoulay, Tsipi, Ben Kasus Nissim, Alexandra, Stavsky, Moran, Melamed, Grace, Stutzmann, Michal, Hershfinkel, Ora, Kofman, Israel, Sekler
Publikováno v:
Cell reports. 41(10)
Impaired phosphodiesterase (PDE) function and mitochondrial Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc47bfc1b28f57c50509d3c8e10d6628
https://pubmed.ncbi.nlm.nih.gov/36476859
https://pubmed.ncbi.nlm.nih.gov/36476859