Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Opsenica Dejan"'
Autor:
Dmitrović Slavica, Skorić Marijana, Boljević Jelena, Aničić Neda, Božić Dragana, Mišić Danijela, Filipović Vuk, Opsenica Dejan
Publikováno v:
Journal of the Serbian Chemical Society, Vol 81, Iss 9, Pp 999-1012 (2016)
The present study was aimed to investigate the elicitation possibility of the main secondary metabolites production in Nepeta cataria L. and N. pannonica L. plants, by exposing them to synthetic compounds from the group of tetraoxanes and tiophene
Externí odkaz:
https://doaj.org/article/52d1f47f210349e78a157d5b6ce82adc
Autor:
Opsenica Dejan M., Radivojević Jelena, Matić Ivana Z., Štajner Tijana, Knežević-Ušaj Slavica, Đurković-Đaković Olgica, Šolaja Bogdan A.
Publikováno v:
Journal of the Serbian Chemical Society, Vol 80, Iss 11, Pp 1339-1359 (2015)
New cyclohexylidene 1,2,4,5-tetraoxanes with polar guanidine and urea based groups were synthesized and evaluated for antimalarial activity against chloroquine resistant and susceptible Plasmodium falciparum strains. Derivatives showed moderate nM
Externí odkaz:
https://doaj.org/article/df329dab51e94fe78e661c48589bffc9
Autor:
Tot Mikloš, Opsenica Dejan M., Mitrić Milena, Burnett James C., Gomba Laura, Bavari Sina, Šolaja Bogdan A.
Publikováno v:
Journal of the Serbian Chemical Society, Vol 78, Iss 12, Pp 1847-1864 (2013)
Steroidal and adamantane aminoacridine derivatives were prepared and tested as both botulinum neurotoxin (BoNT) inhibitors and antimalarials. Steroid-bound acridines provided good potency against both the BoNT/A and BoNT/B light chains (LCs). The
Externí odkaz:
https://doaj.org/article/75226cb702de4637883a749ade6f9fc9
Autor:
Opsenica Dejan M., Šolaja Bogdan A.
Publikováno v:
Journal of the Serbian Chemical Society, Vol 74, Iss 11, Pp 1155-1193 (2009)
The problem of endemic malaria continues unabated globally. Malaria affects 40 % of the global population, causing an estimated annual mortality of 1.5-2.7 million people. The World Health Organization (WHO) estimates that 90 % of these deaths occur
Externí odkaz:
https://doaj.org/article/66f8dccae7f841c1b6e2aaa6a8d394f9
Autor:
Opsenica Igor, Opsenica Dejan, Jadranin Milka, Smith Kirsten, Milhous Wilbur K., Stratakis Manolis, Šolaja Bogdan
Publikováno v:
Journal of the Serbian Chemical Society, Vol 72, Iss 12, Pp 1181-1190 (2007)
Several dicyclohexylidene tetraoxanes were prepared in order to gain a further insight into structure-activity relationship of this kind of antimalarials. The tetraoxanes 2-5, obtained as a cis/trans mixture, showed pronounced antimalarial activity a
Externí odkaz:
https://doaj.org/article/22ff099dd36949a79ef058aa2ec43c93
Publikováno v:
Journal of the Serbian Chemical Society, Vol 70, Iss 3, Pp 329-345 (2005)
A three-dimensional QSAR pharmacophore model for antimalarial activity of steroidal 1,2,4,5-tetraoxanes was developed from a set of 17 substituted antimalarial derivatives out of 27 analogues that exhibited remarkable in vitro activity (below 100 ng/
Externí odkaz:
https://doaj.org/article/2a701ffd0c4c48f781d2e1bf0a56a04e
Publikováno v:
Journal of the Serbian Chemical Society, Vol 69, Iss 11, Pp 919-922 (2004)
Several C2 symmetrical mixed tetraoxanes were prepared starting from a gemdihydroperoxide and a ketone. The obtained tetraoxanes showed pronounced antimalarial activity against P. falciparum chloroquine resistant W2 and chloroquine susceptible D6 str
Externí odkaz:
https://doaj.org/article/f42d5f3c67f3426a82aaa02b27131044
Publikováno v:
Journal of the Serbian Chemical Society, Vol 68, Iss 4-5, Pp 291-302 (2003)
Mixed tetraoxanes of the 4"-phenyl-substituted cyclohexyl-spirotetraoxacyclohexyl- spirocholate series have been prepared and evaluated as possible antimalarials, antiproliferatives and antimycobacterials. The activity of the (4"R or S)-phenyl series
Externí odkaz:
https://doaj.org/article/2fc48deacf844e8484bf75a4ac2fd707
Publikováno v:
Journal of the Serbian Chemical Society, Vol 67, Iss 7, Pp 465-471 (2002)
An intramolecular steroidal 1,2,4,5-tetraoxane has been synthesised in six steps starting from methyl3-oxo-7α,12α-diacetoxy-5β-cholan-24-oate. The synthesised 1,2,4,5-tetraoxane has moderate in vitro antimalarial activity against P. falciparum str
Externí odkaz:
https://doaj.org/article/8d3f7c6121a242d2912f97d80b7d531d
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