Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Ophelia Rogers"'
Autor:
Jerry L Spivak, Akil Merchant, Donna M Williams, Ophelia Rogers, Wanke Zhao, Amy Duffield, Linda S Resar, Alison R Moliterno, Zhizhuang J Zhao
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0232801 (2020)
The myeloproliferative neoplasms, polycythemia vera, essential thrombocytosis and primary myelofibrosis are hematopoietic stem cell disorders and share driver mutations that either directly activate the thrombopoietin receptor, MPL, or activate it in
Externí odkaz:
https://doaj.org/article/e50e6b55a5c045599a6aaacfc14d5345
Autor:
Brady L. Stein, Donna M. Williams, Christine O’Keefe, Ophelia Rogers, Roxann G. Ingersoll, Jerry L. Spivak, Amit Verma, Jarek P. Maciejewski, Michael A. McDevitt, Alison R. Moliterno
Publikováno v:
Haematologica, Vol 96, Iss 10 (2011)
Background The myeloproliferative neoplasms, essential thrombocytosis, polycythemia vera and primary myelofibrosis, share the same acquired genetic lesion, but the concept of JAK2 V617F serving as the sole lesion responsible for these neoplasms is un
Externí odkaz:
https://doaj.org/article/973542ce9e5d4ee99e958d209f7a50b8
Autor:
Brady L. Stein, Donna M. Williams, Nae-Yuh Wang, Ophelia Rogers, Mary Ann Isaacs, Naveen Pemmaraju, Jerry L. Spivak, Alison R. Moliterno
Publikováno v:
Haematologica, Vol 95, Iss 7 (2010)
Background The JAK2V617F allele burden is a variable measure, determined by the frequency of mitotic recombination events and the expansion of JAK2V617F clones. Since variability in the JAK2V617F allele burden is partly responsible for the distinct p
Externí odkaz:
https://doaj.org/article/7927a7304a3e430fbf3fb6c21b2987c4
Autor:
Alison R. Moliterno, Ophelia Rogers, Theodoros Karantanos, Jerry L. Spivak, Donna M. Williams, Styliani Karanika, Shruti Chaturvedi, Evan M. Braunstein, Linda M.S. Resar, Christopher D. Gocke
Publikováno v:
Blood Adv
The factors underlying the variable presentation and clinical course of myeloproliferative neoplasms (MPNs) remain unclear. The aim of this study was to evaluate the independent effect of sex on MPN presentation and outcomes. A total of 815 patients
Autor:
Liping Li, Jung-Hyun Kim, Wenyan Lu, Donna M. Williams, Joseph Kim, Leslie Cope, Raajit K. Rampal, Richard P. Koche, Lingling Xian, Li Z. Luo, Marija Vasiljevic, Daniel R. Matson, Zhizhuang Joe Zhao, Ophelia Rogers, Matthew C. Stubbs, Karen Reddy, Antonio-Rodriguez Romero, Bethan Psaila, Jerry L. Spivak, Alison R. Moliterno, Linda M. S. Resar
Publikováno v:
Blood
Myeloproliferative neoplasms (MPNs) transform to myelofibrosis (MF) and highly lethal acute myeloid leukemia (AML), although the actionable mechanisms driving progression remain elusive. Here, we elucidate the role of the high mobility group A1 (HMGA
Autor:
Li Luo, Linda M.S. Resar, Donna M. Williams, Burles A. Johnson, Lionel Chia, Noah M. Hahn, Mingxiao Feng, Dominic Dordai, Stephen Desiderio, Jack Mountain, Theodore S. Johnson, Adam K. Aragaki, Ophelia Rogers, David J. McConkey, Wenhao Zhang, Lingling Xian
B cells have been implicated as central regulators of immune responses in settings as diverse as mammalian pregnancy, mucosal tolerance, chronic infection states, autoimmunity, and the tumor microenvironment. Despite the established importance of B c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fca7c880f385244fdb15433e93daf19e
https://doi.org/10.1101/2021.08.25.456776
https://doi.org/10.1101/2021.08.25.456776
Autor:
Wanke Zhao, Akil Merchant, Donna M. Williams, Jerry L. Spivak, Linda S. Resar, Alison R. Moliterno, Zhizhuang Joe Zhao, Ophelia Rogers, Amy S. Duffield
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0232801 (2020)
PLoS ONE, Vol 15, Iss 6, p e0232801 (2020)
The myeloproliferative neoplasms, polycythemia vera, essential thrombocytosis and primary myelofibrosis are hematopoietic stem cell disorders and share driver mutations that either directly activate the thrombopoietin receptor, MPL, or activate it in
Autor:
Jerry L. Spivak, Liping Li, Matthew C. Stubbs, Donna M. Williams, Raajit K. Rampal, Ophelia Rogers, Marija Vasiljevic, Leslie Cope, Alison R. Moliterno, Karen L. Reddy, Richard Koche, Daniel R. Matson, Joseph Kim, Jung-Hyun Kim, Wenyan Lu, Linda M.S. Resar, Lingling Xian, Li Luo, Zhizhuang Joe Zhao
Publikováno v:
Blood. 138:625-625
Introduction: Myeloproliferative neoplasms (MPN) are clonal hematopoietic stem cell (HSC) disorders characterized by hyperactive JAK/STAT signaling and increased risk of transformation to myelofibrosis (MF) and acute myeloid leukemia (AML). However,
Autor:
Wenyan Lu, Linda M.S. Resar, Joseph Kim, Jung-Hyun Kim, Jerry L. Spivak, Lingling Xian, Richard Koche, Ophelia Rogers, Donna M. Williams, Joe Zhao, Karen L. Reddy, Daniel R. Matson, Leslie Cope, Liping Li, Alison R. Moliterno, Raajit K. Rampal
Publikováno v:
Cancer Research. 81:2666-2666
Myeloproliferative neoplasms (MPN) are clonal hematopoietic stem cell (HSC) disorders characterized by hyperactive JAK/STAT signaling and increased risk of transformation to myelofibrosis (MF) and acute myeloid leukemia (AML). However, mechanisms dri
Autor:
Lionel Chia, Li Luo, Adam K. Aragaki, Lingling Xian, Linda M.S. Resar, Donna M. Williams, David J. McConkey, Noah M. Hahn, Ophelia Rogers, Stephen Desiderio, Theodore S. Johnson, Burles A. Johnson
Publikováno v:
Cancer Research. 81:2765-2765
Immunotherapy has revolutionized cancer treatment by improving survival in many cancer subtypes. While tumor infiltrating B (TIL-B) cells correlate with response to immunotherapy in selected solid tumors, they portend resistance to BRAF inhibitors in