Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ophélie Vaillant"'
Autor:
Marcel Garcia, Ophélie Vaillant, Dominique P. Arama, Joëlle Dubois, Ludovic T. Maillard, Jean Martinez, Audrey Gallud, Vincent Lisowski, Marie Maynadier, Nicolas Masurier
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2014, 75C, pp.382-390. ⟨10.1016/j.ejmech.2014.01.044⟩
European Journal of Medicinal Chemistry, Elsevier, 2014, 75C, pp.382-390. ⟨10.1016/j.ejmech.2014.01.044⟩
International audience; : A series of 15 pyrido-imidazo-1,3-diazepin-5-ones and pyrido-1,3-diazepine-2,5-diones were synthesized and their anticancer activities were evaluated. Among tested compounds on a cell lines panel, compound 6a presents the be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55bffd0e315c8eb696dbc616586bae86
https://hal.archives-ouvertes.fr/hal-00952223
https://hal.archives-ouvertes.fr/hal-00952223
Autor:
Lubomir Vezenkov, Vincent Martin, Marie Maynadier, Céline Gandreuil, Jean Martinez, Ilaria Basile, Jean-François Hernandez, Magali Gary-Bobo, Ophélie Vaillant, Marcel Garcia, Muriel Amblard
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 171(2)
Implication of the intracellular proteolytic activity of Cathepsin D (CathD), a lysosomal aspartyl-protease overexpressed in numerous solid tumors, has been evidenced on tumor growth. Its intracellular inhibition by potent inhibitors such as pepstati
Autor:
X. Rebillard, Elise Bouffard, Ophélie Vaillant, Philippe Nirdé, Audrey Gallud, Ilaria Basile, Marie Maynadier, Magali Gary-Bobo, K. El Cheikh, Alain Morere, M. Garcia, P. Puche
Publikováno v:
Current Medicinal Chemistry
Current Medicinal Chemistry, Bentham Science Publishers, 2013, 20 (15), pp.1946-1955. ⟨10.2174/0929867311320150002⟩
Current Medicinal Chemistry, Bentham Science Publishers, 2013, 20 (15), pp.1946-1955. ⟨10.2174/0929867311320150002⟩
International audience; In this mini-review, we focus on different strategies to bring nanotools specifically to cancer cells. We discuss about a better targeting of tumor, combining the characteristics of tumor environment, the increase in nanoparti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bcff9f4ddef5f1ee38ac90e5d60a836
https://hal.archives-ouvertes.fr/hal-00841552
https://hal.archives-ouvertes.fr/hal-00841552
Autor:
Jingxue Shi, Anne-Marie Cathiard, Ophélie Vaillant, Michel Gleizes, Jonathan Lee Tin Wah, Marcel Garcia, Ilaria Basile, M. Saeed Sheikh, Magali Gary-Bobo, Marie Maynadier
Publikováno v:
Molecular cancer research : MCR. 10(11)
Proteasome inhibitors such as bortezomib constitute novel therapeutic agents that are currently in clinical use and in clinical trials. In some neoplasms, cyclin-dependent kinase inhibitors (CKI) such as p21WAF1 have been proposed as key targets of p
Autor:
Marie Maynadier, Laurence Raehm, Ophélie Vaillant, Jean-Olivier Durand, Cédric Rouxel, Marcel Garcia, Ilaria Basile, Youssef Mir, Magali Gary-Bobo, Olivier Mongin, David Brevet, Mireille Blanchard-Desce, Alain Morère
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, 2011, pp.11425-11429. ⟨10.1002/anie.201104765⟩
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2011, pp.11425-11429. ⟨10.1002/anie.201104765⟩
Angewandte Chemie International Edition, 2011, pp.11425-11429. ⟨10.1002/anie.201104765⟩
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2011, pp.11425-11429. ⟨10.1002/anie.201104765⟩
In the context of national systematic screenings for cancer,photodynamic therapy (PDT) has arisen as an alternative tochemo- and radiotherapy for the non-invasive selectivedestruction of small tumors. PDT involves the use of aphotosensitizer which, u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca9f460d661a708dee6c620e6228aec
https://hal.science/hal-00646023
https://hal.science/hal-00646023