Výsledky vyhledávání - "Opetaia Aati"

Effects of Allopurinol Dose Escalation on Bone Erosion and Urate Volume in Gout: A Dual‐Energy Computed Tomography Imaging Study Within a Randomized, Controlled Trial

Autor: Opetaia Aati, Karen Billington, Lisa K. Stamp, Jill Drake, Anthony Doyle, Nicola Dalbeth, Anne Horne, Jordyn Allan, Chris Frampton, Paul Tan

Publikováno v: Arthritis & Rheumatology. 71:1739-1746

OBJECTIVE To examine whether allopurinol dose escalation to achieve serum urate (SU) target can influence bone erosion or monosodium urate (MSU) crystal deposition, as measured by dual-energy computed tomography (DECT) in patients with gout. METHODS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d997cb4f2ab2e3afad8ead23b5aab51b
https://doi.org/10.1002/art.40929

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Relationship of bone erosion with the urate and soft tissue components of the tophus in gout: a dual energy computed tomography study

Autor: Anne Horne, Mark Sapsford, Nicola Dalbeth, Gregory D. Gamble, Opetaia Aati, Anthony Doyle, Julie Knight

Publikováno v: Rheumatology. 56:129-133

Objectives Imaging and pathology studies have established a close relationship between tophus and bone erosion in gout. The tophus is an organized structure consisting of urate crystals and chronic inflammatory tissue. The aim of this work was to exa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2456a94f03731c795aa1d31529012314
https://doi.org/10.1093/rheumatology/kew383

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Development of a patient-reported outcome measure of tophus burden: the Tophus Impact Questionnaire (TIQ-20)

Autor: Jill Drake, Nicola Dalbeth, Paul Tan, Richard J. Siegert, Meaghan E House, Lisa K. Stamp, William J. Taylor, Anne Horne, Opetaia Aati

Publikováno v: Annals of the Rheumatic Diseases. 74:2144-2150

BackgroundTophus burden is currently measured using physical examination and imaging methods. The aim of this study was to develop a patient-reported outcome (PRO) tool to assess tophus burden in people with gout.MethodsThe responses from interviews

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d65ee8e29f0e263d297b934bbd1a649
https://doi.org/10.1136/annrheumdis-2014-205671

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Zoledronate for prevention of bone erosion in tophaceous gout: a randomised, double-blind, placebo-controlled trial

Autor: Ashika Chhana, Meaghan E House, Ian R. Reid, Nicola Dalbeth, Fiona M McQueen, Gregory D. Gamble, Mark Roger, Opetaia Aati, Anthony Doyle, Anne Horne

Publikováno v: Annals of the Rheumatic Diseases. 73:1044-1051

Objectives The osteoclast has been implicated in development of bone erosion in gout. The aim of this study was to determine whether zoledronate, a potent antiosteoclast drug, influences bone erosion in people with tophaceous gout. Methods This was a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a2ce26a9bff003026f0b59b5e33a42
https://doi.org/10.1136/annrheumdis-2013-205036

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Do Patient Preferences for Core Outcome Domains for Chronic Gout Studies Support the Validity of Composite Response Criteria?

Autor: Melanie Brown, William J. Taylor, Nicola Dalbeth, Mark Weatherall, Opetaia Aati

Publikováno v: Arthritis Care & Research. 65:1259-1264

Objective To determine patient-derived weights or prioritization for core outcome domains in chronic gout clinical studies. Methods Three patient groups participated in a conjoint decision-making exercise using 1000Minds software, which asked partici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bfaa74a1421dffcb955ebea97c747052
https://doi.org/10.1002/acr.21955

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Tendon involvement in the feet of patients with gout: a dual-energy CT study

Autor: Nicola Dalbeth, Ramanamma Kalluru, Fiona M McQueen, Opetaia Aati, Anthony Doyle, Anne Horne

Publikováno v: Annals of the Rheumatic Diseases. 72:1545-1548

To examine the frequency and patterns of monosodium urate (MSU) crystal deposition in tendons and ligaments in patients with gout using dual-energy CT (DECT).Ninety-two patients with tophaceous gout had DECT scanning of both feet. Two readers scored

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a92b782504a32fe64e6b5eeb1cb2fb0
https://doi.org/10.1136/annrheumdis-2012-202786

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Dual-Energy CT of Urate Deposits in Costal Cartilage and Intervertebral Disks of Patients With Tophaceous Gout and Age-Matched Controls

Autor: Alexander Carr, Nicola Dalbeth, Opetaia Aati, Anthony Doyle, Fiona M McQueen

Publikováno v: AJR. American journal of roentgenology. 206(5)

OBJECTIVE. The purpose of this study was to investigate whether monosodium urate (MSU) deposits could be identified within the abdomen and axial skeleton of patients with tophaceous gout using dual-energy CT (DECT). CONCLUSION. DECT of the abdomen, c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52919f0dac329e28d813b64d00f06fc0
https://pubmed.ncbi.nlm.nih.gov/26958708

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Assessment of Tophus Size

Autor: Nicola Dalbeth, Qiliang Liu, Meaghan E House, Fiona M McQueen, Anne Horne, Opetaia Aati, Anthony Doyle, Angela Gao

Publikováno v: JCR: Journal of Clinical Rheumatology. 18:23-27

Dual-energy computed tomography (DECT) has recently been described as a sensitive method to detect urate deposits in patients with gout.The aim of this study was to compare the reproducibility of DECT with various physical measurement methods of toph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5146d6fd16fd9ea55df4b6dcb1208586
https://doi.org/10.1097/rhu.0b013e31823e5cda

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