Zobrazeno 1 - 10
of 338
pro vyhledávání: '"Operant self-administration paradigm"'
Autor:
Lindsey Felth, Sarah Gooding, Randi Foxhall, Zachary Rosa, Kyle Ireton, Izabella Sall, Joshua Gipoor, Anirudh Gaur, Madeline King, Noah Dirks, Cheryl A. Whistler, Jennifer L. Whistler
Opioid drugs are potent analgesics that mimic the endogenous opioid peptides, endorphins and enkephalins, by activating the µ-opioid receptor. Opioid use is limited by side effects, including significant risk of opioid use disorder. Improvement of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::147aa5c4b20c5ebfbdb100a7b5b9d480
https://doi.org/10.1101/2023.03.30.534994
https://doi.org/10.1101/2023.03.30.534994
Autor:
Martí-Prats, Lucía1, Zornoza, Teodoro1, López-Moreno, José2, Granero, Luis1, Polache, Ana1 ana.polache@uv.es
Publikováno v:
Psychopharmacology. Oct2015, Vol. 232 Issue 19, p3597-3606. 10p. 1 Diagram, 4 Graphs.
Publikováno v:
Psychopharmacology. 232:3597-3606
Previous experiments in our laboratory have shown that d-penicillamine (DP) (acetaldehyde sequestering agent) is able to block the increase in ethanol consumption observed after a period of imposed deprivation (the so-called alcohol deprivation effec
Akademický článek
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Publikováno v:
Drug Week; 4/21/2023, p416-416, 1p
Autor:
SUTERA, Flavia Maria, DE CARO, Viviana, GIANNOLA, Libero Italo, CANNIZZARO, Carla, Incandela, G
Rewarding and reinforcing properties of alcohol have been shown to be mediated by activation of the mesolimbic dopaminergic system. Experimental evidences suggest that mesolimbic dopamine system is hypofunctional in addicted brain; further, reduced d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3658::4a9f90ea4d7cf684d7664d91248e73f8
http://hdl.handle.net/10447/99900
http://hdl.handle.net/10447/99900
Publikováno v:
Pharmacology Biochemistry and Behavior. 46:315-322
The effect of intermittent footshock stress (0.8 mA; 0.2 s on; 40 s off on the average; for 10 min/day) on oral fentanyl (50 or 75 micrograms/ml) self-administration (SA) in operant chambers was examined in male rats. In Experiment 1, after 1 month o
Autor:
Jaehne, Emily J., McInerney, Elizabeth, Sharma, Ronan, Genders, Shannyn G., Djouma, Elvan, van den Buuse, Maarten
Publikováno v:
Biology (2079-7737); Jun2023, Vol. 12 Issue 6, p799, 17p
Autor:
Lovelock, Dennis F.1 (AUTHOR), Liu, Wen1 (AUTHOR), Langston, Sarah E.1 (AUTHOR), Liu, Jiaqi1 (AUTHOR), Van Voorhies, Kalynn1 (AUTHOR), Giffin, Kaitlin A.1 (AUTHOR), Vetreno, Ryan P.1,2 (AUTHOR), Crews, Fulton T.1,2,3 (AUTHOR), Besheer, Joyce1,2 (AUTHOR) jbesheer@med.unc.edu
Publikováno v:
Addiction Biology. May2022, Vol. 27 Issue 3, p1-13. 13p.
Autor:
Flavia Maria Sutera, Fulvio Plescia, Viviana De Caro, Carla Cannizzaro, Libero Italo Giannola, Gianluca Lavanco
Publikováno v:
Behavioural Brain Research. 310:109-118
The mesolimbic dopamine (DA) system plays a key role in drug reinforcement and is involved in the development of alcohol addiction. Manipulation of the DAergic system represents a promising strategy to control drug-seeking behavior. Previous studies