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Open Targets: 10 years of partnership in target discovery.

Autor: Hulcoop DG, Trynka G, McDonagh EM

Publikováno v: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2024 Dec 17. Date of Electronic Publication: 2024 Dec 17.

Empowering the discovery of novel target-disease associations via machine learning approaches in the open targets platform

Autor: Yingnan Han, Katherine Klinger, Deepak K. Rajpal, Cheng Zhu, Erin Teeple

Publikováno v: BMC Bioinformatics, Vol 23, Iss 1, Pp 1-19 (2022)

Abstract Background The Open Targets (OT) Platform integrates a wide range of data sources on target-disease associations to facilitate identification of potential therapeutic drug targets to treat human diseases. However, due to the complexity that

Externí odkaz: https://doaj.org/article/4eb572ecb500418a8a1987ce45810b5e

Identification of Potential Therapeutic Targets on the Level of DNA/mRNAs, Proteins and Metabolites: A Systematic Mapping Review of Scientific Texts’ Fragments from Open Targets

Autor: Pavel V. Pogodin, Olga I. Kiseleva, Ekaterina V. Ilgisonis

Publikováno v: Current Issues in Molecular Biology, Vol 45, Iss 4, Pp 3406-3418 (2023)

Database records contain useful information, which is readily available, but, unfortunately, limited compared to the source (publications). Our study reviewed the text fragments supporting the association between the biological macromolecules and dis

Externí odkaz: https://doaj.org/article/0513cb6bf0ff40b4be871fbefbce49cd

Predicting Behavioral Target Mastery With Age, Intensity and Duration, Open Targets, and Maintenance Failure With Applied Behavior Analysis in Individuals With Autism.

Autor: Peterson T; Special Education, The Oxford Center, Brighton, USA., Dodson J; Applied Behavior Analysis, The Oxford Center, Brighton, USA., Strale F Jr; Biostatistics, The Oxford Center, Brighton, USA.

Publikováno v: Cureus [Cureus] 2024 Feb 10; Vol. 16 (2), pp. e53964. Date of Electronic Publication: 2024 Feb 10 (Print Publication: 2024).