Zobrazeno 1 - 10
of 843
pro vyhledávání: '"Open chromatin"'
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Open chromatin regions (OCRs) play a crucial role in transcriptional regulation and gene expression. In recent years, there has been a growing interest in using plasma cell-free DNA (cfDNA) sequencing data to detect OCRs. By analyzing the characteris
Externí odkaz:
https://doaj.org/article/d151a02571fb4a418fdab822ccead36b
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Cell‐free DNA (cfDNA) fragmentation patterns have immense potential for early cancer detection. However, the definition of fragmentation varies, ranging from the entire genome to specific genomic regions. These patterns have not been syste
Externí odkaz:
https://doaj.org/article/6834aeb9d3b34f918d64ea91979e7895
Autor:
Juan M. Debernardi, German Burguener, Kerry Bubb, Qiujie Liu, Christine Queitsch, Jorge Dubcovsky
Publikováno v:
BMC Plant Biology, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background The genetic information contained in the genome of an organism is organized in genes and regulatory elements that control gene expression. The genomes of multiple plants species have already been sequenced and the gene repertory h
Externí odkaz:
https://doaj.org/article/a1bb3d925deb42e380d744ed036240c5
Autor:
Betelehem Solomon Bera, Taylor V. Thompson, Eric Sosa, Hiroko Nomaru, David Reynolds, Robert A. Dubin, Shahina B. Maqbool, Deyou Zheng, Bernice E. Morrow, John M. Greally, Masako Suzuki
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Background Single-cell technologies to analyze transcription and chromatin structure have been widely used in many research areas to reveal the functions and molecular properties of cells at single-cell resolution. Sample multiplexing techni
Externí odkaz:
https://doaj.org/article/f1b57dbd9eda4373b99c5082f8dfd9c5
Autor:
Xionghui Zhou, Haizi Zheng, Hailu Fu, Kelsey L. Dillehay McKillip, Susan M. Pinney, Yaping Liu
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-15 (2022)
Abstract The fine-scale cell-free DNA fragmentation patterns in early-stage cancers are poorly understood. We developed a de novo approach to characterize the cell-free DNA fragmentation hotspots from plasma whole-genome sequencing. Hotspots are enri
Externí odkaz:
https://doaj.org/article/9ca69ea715234f7eacc84e879ec4296c
Publikováno v:
Physiological Reports, Vol 11, Iss 17, Pp n/a-n/a (2023)
Abstract Epidemiological studies have shown that patients who recovered from acute kidney injury (AKI) may subsequently develop chronic kidney disease (CKD). AKI is primarily caused by renal hypoxia, and it causes epigenetic alterations, known as hyp
Externí odkaz:
https://doaj.org/article/fce23d0b76bc442a88a2d700f8114393
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Jiayi Ren, Yuqian Liu, Xiaoyan Zhu, Xuwen Wang, Yifei Li, Yuxin Liu, Wenqing Hu, Xuanping Zhang, Jiayin Wang
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Open chromatin regions are the genomic regions associated with basic cellular physiological activities, while chromatin accessibility is reported to affect gene expressions and functions. A basic computational problem is to efficiently estimate open
Externí odkaz:
https://doaj.org/article/0c2a3d3b7d33405ab22e00fbbb4dd384
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-7 (2022)
Abstract Background New genes continuously emerge from non-coding DNA or by diverging from existing genes, but most of them are rapidly lost and only a few become fixed within the population. We hypothesized that young genes are subject to transcript
Externí odkaz:
https://doaj.org/article/3743f933b1b54a3298658243138e1c80