Differential miRNA Expression Contributes to Emergence of Multiple Cancer Stem Cell Subpopulations in Human Colorectal Cancer.

Autor: Stark VA; Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA.; Center for Translational Cancer Research, Helen F. Graham Cancer Center & Research Institute, Newark, DE 19713, USA., Facey COB; Center for Translational Cancer Research, Helen F. Graham Cancer Center & Research Institute, Newark, DE 19713, USA., Opdenaker L; Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA.; Center for Translational Cancer Research, Helen F. Graham Cancer Center & Research Institute, Newark, DE 19713, USA., Fields JZ; CATX Inc, Princeton NJ USA., Boman BM; Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA.; Center for Translational Cancer Research, Helen F. Graham Cancer Center & Research Institute, Newark, DE 19713, USA.; Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Feb 06. Date of Electronic Publication: 2023 Feb 06.

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MicroRNA Expression Profiling of Normal and Malignant Human Colonic Stem Cells Identifies miRNA92a as a Regulator of the LRIG1 Stem Cell Gene.

Autor: Viswanathan V; Center for Translational Cancer Research, Helen F Graham Cancer Center and Research Institute, Newark, DE 19713, USA.; Department of Biological Sciences, University of Delaware, Newark, DE 19711, USA., Opdenaker L; Center for Translational Cancer Research, Helen F Graham Cancer Center and Research Institute, Newark, DE 19713, USA.; Department of Biological Sciences, University of Delaware, Newark, DE 19711, USA., Modarai S; Center for Translational Cancer Research, Helen F Graham Cancer Center and Research Institute, Newark, DE 19713, USA.; Department of Biological Sciences, University of Delaware, Newark, DE 19711, USA., Fields JZ; CA*TX Inc., Princeton, NJ 08542, USA., Gonye G; Nanostring Technologies, Seattle, WA 98109, USA.; Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University & Kimmel Cancer Center, Philadelphia, PA 19107, USA., Boman BM; Center for Translational Cancer Research, Helen F Graham Cancer Center and Research Institute, Newark, DE 19713, USA.; Department of Biological Sciences, University of Delaware, Newark, DE 19711, USA.; Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University & Kimmel Cancer Center, Philadelphia, PA 19107, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2020 Apr 17; Vol. 21 (8). Date of Electronic Publication: 2020 Apr 17.

An miRNA Expression Signature for the Human Colonic Stem Cell Niche Distinguishes Malignant from Normal Epithelia.

Autor: Viswanathan V; Center for Translational Cancer Research, Helen F Graham Cancer Center and Research Institute, Newark, Delaware.; Department of Biological Sciences, University of Delaware, Newark, Delaware.; Department of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, Massachusetts., Damle S; Thomas Jefferson University and Kimmel Cancer Center, Philadelphia, Pennsylvania., Zhang T; Center for Translational Cancer Research, Helen F Graham Cancer Center and Research Institute, Newark, Delaware.; Department of Biological Sciences, University of Delaware, Newark, Delaware.; Thomas Jefferson University and Kimmel Cancer Center, Philadelphia, Pennsylvania., Opdenaker L; Center for Translational Cancer Research, Helen F Graham Cancer Center and Research Institute, Newark, Delaware.; Department of Biological Sciences, University of Delaware, Newark, Delaware., Modarai S; Center for Translational Cancer Research, Helen F Graham Cancer Center and Research Institute, Newark, Delaware.; Department of Biological Sciences, University of Delaware, Newark, Delaware., Accerbi M; Department of Plant and Soil Sciences, Delaware Biotechnology Institute, Newark, Delaware., Schmidt S; Department of Plant and Soil Sciences, Delaware Biotechnology Institute, Newark, Delaware., Green P; Department of Plant and Soil Sciences, Delaware Biotechnology Institute, Newark, Delaware., Galileo D; Department of Biological Sciences, University of Delaware, Newark, Delaware., Palazzo J; Thomas Jefferson University and Kimmel Cancer Center, Philadelphia, Pennsylvania., Fields J; CA*TX Inc., Gladwyne, Pennsylvania., Haghighat S; Center for Translational Cancer Research, Helen F Graham Cancer Center and Research Institute, Newark, Delaware.; Department of Biological Sciences, University of Delaware, Newark, Delaware.; Thomas Jefferson University and Kimmel Cancer Center, Philadelphia, Pennsylvania., Rigoutsos I; Thomas Jefferson University and Kimmel Cancer Center, Philadelphia, Pennsylvania., Gonye G; Thomas Jefferson University and Kimmel Cancer Center, Philadelphia, Pennsylvania.; Nanostring Technologies, Seattle, Washington., Boman BM; Center for Translational Cancer Research, Helen F Graham Cancer Center and Research Institute, Newark, Delaware. BrBoman@ChristianaCare.org.; Department of Biological Sciences, University of Delaware, Newark, Delaware.; Thomas Jefferson University and Kimmel Cancer Center, Philadelphia, Pennsylvania.

Publikováno v: Cancer research [Cancer Res] 2017 Jul 15; Vol. 77 (14), pp. 3778-3790. Date of Electronic Publication: 2017 May 09.