Effect of Therapeutic Drug Monitoring on Adherence and Blood Pressure: A Multicenter Randomized Clinical Trial.

Autor: Halvorsen LV; Department of Nephrology, Oslo University Hospital Ullevål, Oslo, Norway.; Section for Cardiovascular and Renal Research, Oslo University Hospital Ullevål, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Søraas CL; Section for Cardiovascular and Renal Research, Oslo University Hospital Ullevål, Oslo, Norway.; Section for Environmental and Occupational Medicine, Oslo University Hospital Ullevål, Oslo, Norway., Larstorp ACK; Section for Cardiovascular and Renal Research, Oslo University Hospital Ullevål, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Medical Biochemistry, Oslo University Hospital Ullevål, Oslo, Norway., Hjørnholm U; Section for Cardiovascular and Renal Research, Oslo University Hospital Ullevål, Oslo, Norway., Kjær VN; Section for Cardiovascular and Renal Research, Oslo University Hospital Ullevål, Oslo, Norway., Liestøl K; Department of Informatics, University of Oslo, Oslo, Norway., Aune A; Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Heart Disease, Haukeland University Hospital, Bergen, Norway., Olsen E; Norwegian University of Science and Technology, Trondheim, Norway.; Department of Emergency Medicine, St. Olav's University Hospital, Trondheim, Norway., Brobak KM; Metabolic and Renal Research Group, UiT, The Arctic University of Norway, Tromsø, Norway.; Section of Nephrology, University Hospital of North Norway, Tromsø, Norway., Bergland OU; Section for Cardiovascular and Renal Research, Oslo University Hospital Ullevål, Oslo, Norway., Rognstad S; Section for Cardiovascular and Renal Research, Oslo University Hospital Ullevål, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Pharmacology, Oslo University Hospital Ullevål, Oslo, Norway., Aarskog NR; Section for Cardiovascular and Renal Research, Oslo University Hospital Ullevål, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Acute Medicine, Oslo University Hospital Ullevål, Oslo, Norway., Heimark S; Department of Nephrology, Oslo University Hospital Ullevål, Oslo, Norway.; Section for Cardiovascular and Renal Research, Oslo University Hospital Ullevål, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Fadl Elmula FEM; Section for Cardiovascular and Renal Research, Oslo University Hospital Ullevål, Oslo, Norway., Gerdts E; Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Heart Disease, Haukeland University Hospital, Bergen, Norway., Mo R; Department of Emergency Medicine, St. Olav's University Hospital, Trondheim, Norway.; Department of Cardiology, St. Olav's University Hospital, Trondheim, Norway., Solbu MD; Metabolic and Renal Research Group, UiT, The Arctic University of Norway, Tromsø, Norway.; Section of Nephrology, University Hospital of North Norway, Tromsø, Norway., Opdal MS; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Pharmacology, Oslo University Hospital Ullevål, Oslo, Norway., Kjeldsen SE; Department of Nephrology, Oslo University Hospital Ullevål, Oslo, Norway.; Section for Cardiovascular and Renal Research, Oslo University Hospital Ullevål, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Cardiology, Oslo University Hospital Ullevål, Oslo, Norway., Rostrup M; Section for Cardiovascular and Renal Research, Oslo University Hospital Ullevål, Oslo, Norway.; Department of Acute Medicine, Oslo University Hospital Ullevål, Oslo, Norway.; Department of Behavioral Sciences, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Høieggen A; Department of Nephrology, Oslo University Hospital Ullevål, Oslo, Norway.; Section for Cardiovascular and Renal Research, Oslo University Hospital Ullevål, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Publikováno v: American journal of hypertension [Am J Hypertens] 2024 Sep 16; Vol. 37 (10), pp. 826-836.

Usefulness of measuring the serum concentration of antihypertensive drugs in uncontrolled hypertension.

Autor: Opdal MS, Rognstad S, Edvardsen F, Halvorsen LV, Mo R, Gustavsen I, Larstorp ACK, Søraas CL, Helland A

Publikováno v: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke [Tidsskr Nor Laegeforen] 2024 Jul 18; Vol. 144 (9). Date of Electronic Publication: 2024 Jul 18 (Print Publication: 2024).

Development of UHPLC-MS/MS methods to quantify 25 antihypertensive drugs in serum in a cohort of patients treated for hypertension.

Autor: Thorstensen CW; Department of Pharmacology, Oslo University Hospital, Ullevål, Oslo, Norway., Clasen PE; Department of Pharmacology, Oslo University Hospital, Ullevål, Oslo, Norway., Rognstad S; Department of Pharmacology, Oslo University Hospital, Ullevål, Oslo, Norway; Section of Cardiovascular and Renal Research, Oslo University Hospital, Ullevål, Oslo, Norway; Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway. Electronic address: stirog@ous-hf.no., Haldsrud R; Department of Pharmacology, Oslo University Hospital, Ullevål, Oslo, Norway., Føreid S; Department of Pharmacology, Oslo University Hospital, Ullevål, Oslo, Norway., Helstrøm T; Department of Pharmacology, Oslo University Hospital, Ullevål, Oslo, Norway., Bergland OU; Section of Cardiovascular and Renal Research, Oslo University Hospital, Ullevål, Oslo, Norway; Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway., Halvorsen LV; Section of Cardiovascular and Renal Research, Oslo University Hospital, Ullevål, Oslo, Norway; Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway; Department of Nephrology, Oslo University Hospital, Ullevål, Oslo, Norway., Aune A; Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Heart Disease, Haukeland University Hospital, Bergen, Norway., Olsen E; Department of Cardiology, St Olav University Hospital, Trondheim, Norway; Norwegian University of Science and Technology, Trondheim, Norway., Brobak KM; Section of Nephrology, University Hospital of North Norway, Tromsø, Norway; Metabolic and Renal Research Group, The Arctic University of Norway, Tromsø, Norway., Høieggen A; Section of Cardiovascular and Renal Research, Oslo University Hospital, Ullevål, Oslo, Norway; Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway; Department of Nephrology, Oslo University Hospital, Ullevål, Oslo, Norway., Gustavsen I; Department of Pharmacology, Oslo University Hospital, Ullevål, Oslo, Norway., Larstorp ACK; Section of Cardiovascular and Renal Research, Oslo University Hospital, Ullevål, Oslo, Norway; Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway; Department of Medical Biochemistry, Oslo University Hospital, Ullevål, Oslo, Norway., Søraas CL; Section of Cardiovascular and Renal Research, Oslo University Hospital, Ullevål, Oslo, Norway; Section for Environmental and Occupational Medicine, Oslo University Hospital, Ullevål, Oslo, Norway., Opdal MS; Department of Pharmacology, Oslo University Hospital, Ullevål, Oslo, Norway; Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway.

Publikováno v: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2022 Sep 20; Vol. 219, pp. 114908. Date of Electronic Publication: 2022 Jun 23.

Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations.

Autor: Bergland OU; From the Section for Cardiovascular and Renal Research (O.U.B., L.V.H., C.L.S., U.H., V.N.K., S.R., Y.M.F., S.H., M.R., S.E.K., A.H., A.C.K.L., F.E.M.F.E.).; Oslo University Hospital Ullevål; Institute of Clinical Medicine (O.U.B., L.V.H., S.R., S.H., S.E.K., A.H., A.C.K.L.), University of Oslo., Halvorsen LV; From the Section for Cardiovascular and Renal Research (O.U.B., L.V.H., C.L.S., U.H., V.N.K., S.R., Y.M.F., S.H., M.R., S.E.K., A.H., A.C.K.L., F.E.M.F.E.).; Department of Nephrology (L.V.H., S.H., A.H.).; Oslo University Hospital Ullevål; Institute of Clinical Medicine (O.U.B., L.V.H., S.R., S.H., S.E.K., A.H., A.C.K.L.), University of Oslo., Søraas CL; From the Section for Cardiovascular and Renal Research (O.U.B., L.V.H., C.L.S., U.H., V.N.K., S.R., Y.M.F., S.H., M.R., S.E.K., A.H., A.C.K.L., F.E.M.F.E.).; Section for Environmental and Occupational Medicine (C.L.S.)., Hjørnholm U; From the Section for Cardiovascular and Renal Research (O.U.B., L.V.H., C.L.S., U.H., V.N.K., S.R., Y.M.F., S.H., M.R., S.E.K., A.H., A.C.K.L., F.E.M.F.E.)., Kjær VN; From the Section for Cardiovascular and Renal Research (O.U.B., L.V.H., C.L.S., U.H., V.N.K., S.R., Y.M.F., S.H., M.R., S.E.K., A.H., A.C.K.L., F.E.M.F.E.)., Rognstad S; From the Section for Cardiovascular and Renal Research (O.U.B., L.V.H., C.L.S., U.H., V.N.K., S.R., Y.M.F., S.H., M.R., S.E.K., A.H., A.C.K.L., F.E.M.F.E.).; Department of Pharmacology (S.R., C.W.T., M.S.O.).; Oslo University Hospital Ullevål; Institute of Clinical Medicine (O.U.B., L.V.H., S.R., S.H., S.E.K., A.H., A.C.K.L.), University of Oslo., Brobak KM; Metabolic and Renal Research Group (K.M.B., M.D.S.), University Hospital of North Norway, Tromsø.; UiT The Arctic University of Norway, and Section of Nephrology (K.M.B., M.D.S.), University Hospital of North Norway, Tromsø., Aune A; Department of Clinical Science, University of Bergen (A.A., E.G.).; Department of Heart Disease, Haukeland University Hospital, Bergen (A.A., E.G.)., Olsen E; Department of Cardiology, Trondheim University Hospital, University of Trondheim (E.O., R.M.)., Fauchald YM; From the Section for Cardiovascular and Renal Research (O.U.B., L.V.H., C.L.S., U.H., V.N.K., S.R., Y.M.F., S.H., M.R., S.E.K., A.H., A.C.K.L., F.E.M.F.E.)., Heimark S; From the Section for Cardiovascular and Renal Research (O.U.B., L.V.H., C.L.S., U.H., V.N.K., S.R., Y.M.F., S.H., M.R., S.E.K., A.H., A.C.K.L., F.E.M.F.E.).; Department of Nephrology (L.V.H., S.H., A.H.).; Oslo University Hospital Ullevål; Institute of Clinical Medicine (O.U.B., L.V.H., S.R., S.H., S.E.K., A.H., A.C.K.L.), University of Oslo., Thorstensen CW; Department of Pharmacology (S.R., C.W.T., M.S.O.)., Liestøl K; Department of Informatics (K.L.), University of Oslo., Solbu MD; Metabolic and Renal Research Group (K.M.B., M.D.S.), University Hospital of North Norway, Tromsø.; UiT The Arctic University of Norway, and Section of Nephrology (K.M.B., M.D.S.), University Hospital of North Norway, Tromsø., Gerdts E; Department of Clinical Science, University of Bergen (A.A., E.G.).; Department of Heart Disease, Haukeland University Hospital, Bergen (A.A., E.G.)., Mo R; Department of Cardiology, Trondheim University Hospital, University of Trondheim (E.O., R.M.)., Rostrup M; From the Section for Cardiovascular and Renal Research (O.U.B., L.V.H., C.L.S., U.H., V.N.K., S.R., Y.M.F., S.H., M.R., S.E.K., A.H., A.C.K.L., F.E.M.F.E.).; Department of Acute Medicine (M.R., F.E.M.F.E.).; Department of Behavioral Sciences, Institute of Basic Medical Sciences (M.R.), University of Oslo., Kjeldsen SE; From the Section for Cardiovascular and Renal Research (O.U.B., L.V.H., C.L.S., U.H., V.N.K., S.R., Y.M.F., S.H., M.R., S.E.K., A.H., A.C.K.L., F.E.M.F.E.).; Department of Cardiology (S.E.K.).; Oslo University Hospital Ullevål; Institute of Clinical Medicine (O.U.B., L.V.H., S.R., S.H., S.E.K., A.H., A.C.K.L.), University of Oslo., Høieggen A; From the Section for Cardiovascular and Renal Research (O.U.B., L.V.H., C.L.S., U.H., V.N.K., S.R., Y.M.F., S.H., M.R., S.E.K., A.H., A.C.K.L., F.E.M.F.E.).; Department of Nephrology (L.V.H., S.H., A.H.).; Oslo University Hospital Ullevål; Institute of Clinical Medicine (O.U.B., L.V.H., S.R., S.H., S.E.K., A.H., A.C.K.L.), University of Oslo., Opdal MS; Department of Pharmacology (S.R., C.W.T., M.S.O.)., Larstorp ACK; From the Section for Cardiovascular and Renal Research (O.U.B., L.V.H., C.L.S., U.H., V.N.K., S.R., Y.M.F., S.H., M.R., S.E.K., A.H., A.C.K.L., F.E.M.F.E.).; Department of Medical Biochemistry (A.C.K.L.).; Oslo University Hospital Ullevål; Institute of Clinical Medicine (O.U.B., L.V.H., S.R., S.H., S.E.K., A.H., A.C.K.L.), University of Oslo., Fadl Elmula FEM; From the Section for Cardiovascular and Renal Research (O.U.B., L.V.H., C.L.S., U.H., V.N.K., S.R., Y.M.F., S.H., M.R., S.E.K., A.H., A.C.K.L., F.E.M.F.E.).; Department of Acute Medicine (M.R., F.E.M.F.E.).

Publikováno v: Hypertension (Dallas, Tex. : 1979) [Hypertension] 2021 Sep; Vol. 78 (3), pp. 617-628. Date of Electronic Publication: 2021 Jul 19.

Developing a rapid semi-automated sample preparation with alkaline hydrolysis in a 96-well plate for quantification of 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid in urine samples by UHPLC-MS/MS.

Autor: Müller LD; Section of Clinical Pharmacology, Department of Pharmacology, Oslo University Hospital, N-0424 Oslo, Norway. Electronic address: UXMUIL@ous-hf.no., Opdal MS; Section of Clinical Pharmacology, Department of Pharmacology, Oslo University Hospital, N-0424 Oslo, Norway; Institute of Clinical medicine, University of Oslo, Postbox 1171 Blindern 0318 Oslo, Norway.

Publikováno v: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2018 Nov 30; Vol. 161, pp. 296-304. Date of Electronic Publication: 2018 Aug 23.