Výsledky vyhledávání - "Opalina Vetrichelvan"

Akademický článek

Bergamottin a CYP3A inhibitor found in grapefruit juice inhibits prostate cancer cell growth by downregulating androgen receptor signaling and promoting G0/G1 cell cycle block and apoptosis.

Autor: Opalina Vetrichelvan, Priyatham Gorjala, Oscar Goodman, Ranjana Mitra

Publikováno v: PLoS ONE, Vol 16, Iss 9, p e0257984 (2021)

Prostate cancer is the second leading cause of cancer related death in American men. Several therapies have been developed to treat advanced prostate cancer, but these therapies often have severe side effects. To improve the outcome with fewer side e

Externí odkaz: https://doaj.org/article/189da2492d3d4aeea0a10690886dd5d5

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Bergamottin a CYP3A inhibitor found in grapefruit juice inhibits prostate cancer cell growth by downregulating androgen receptor signaling causing cell cycle block and apoptosis

Autor: Opalina Vetrichelvan, Priyatham Gorjala, Oscar B. Goodman, Ranjana Mitra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d35abb3ef4514ddf8303691073201f0
https://doi.org/10.1101/2021.05.06.442999

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Abstract 3475: CYP3A5 inhibitor bergamottin present in grape fruit extract blocks prostate cancer cell growth

Autor: Ranjana Mitra, Opalina Vetrichelvan, Priyatham Gorjala, Oscar B. Goodman

Publikováno v: Cancer Research. 80:3475-3475

Background: Previous research has revealed that the androgen receptor (AR), which upon activation goes to the nucleus, is the driving force of prostate cancer growth. Once activated, AR promotes transcription of genes responsible for promoting cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d653509cc58b30158026eafc6576ad5
https://doi.org/10.1158/1538-7445.am2020-3475

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