Multiscale heterogeneity in gastric adenocarcinoma evolution is an obstacleto precision medicine

Autor: Röcken, C., Amallraja, A., Halske, C., Opašić, L., Traulsen, A., Behrens, H., Krüger, S., Liu, A., Haag, J., Egberts, J., Rosenstiel, P., Meissner, T.

Publikováno v: Research Square

Purpose: Cancer is a somatic evolutionary disease. Using multiregional whole exome sequencing, we tested the effect of somatic evolution on intratumoral heterogeneity and its putative clinical and biological implications in adenocarcinomas of the sto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1874::3c2dd7530063d2f292dd85b91724cc46
https://hdl.handle.net/21.11116/0000-0007-9ECA-421.11116/0000-0007-9EC8-6

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Embryo-Like Features in Developing Bacillus subtilis Biofilms.

Autor: Futo M; Laboratory of Evolutionary Genetics, Division of Molecular Biology, Ruđer Bošković Institute, Zagreb, Croatia., Opašić L; Laboratory of Evolutionary Genetics, Division of Molecular Biology, Ruđer Bošković Institute, Zagreb, Croatia.; Department for Evolutionary Theory, Max Planck Institute for Evolutionary Biology, Plön, Germany., Koska S; Laboratory of Evolutionary Genetics, Division of Molecular Biology, Ruđer Bošković Institute, Zagreb, Croatia., Čorak N; Laboratory of Evolutionary Genetics, Division of Molecular Biology, Ruđer Bošković Institute, Zagreb, Croatia., Široki T; Faculty of Electrical Engineering and Computing, University of Zagreb, Zagreb, Croatia., Ravikumar V; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs. Lyngby, Denmark., Thorsell A; Proteomics Core Facility, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Lenuzzi M; Laboratory of Evolutionary Genetics, Division of Molecular Biology, Ruđer Bošković Institute, Zagreb, Croatia.; Department of Evolutionary Biology, Max Planck Institute for Developmental Biology, Tübingen, Germany., Kifer D; Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia., Domazet-Lošo M; Faculty of Electrical Engineering and Computing, University of Zagreb, Zagreb, Croatia., Vlahoviček K; Bioinformatics Group, Division of Biology, Faculty of Science, University of Zagreb, Zagreb, Croatia.; School of Biosciences, University of Skövde, Skövde, Sweden., Mijakovic I; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs. Lyngby, Denmark.; Systems and Synthetic Biology Division, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden., Domazet-Lošo T; Laboratory of Evolutionary Genetics, Division of Molecular Biology, Ruđer Bošković Institute, Zagreb, Croatia.; Catholic University of Croatia, Zagreb, Croatia.

Publikováno v: Molecular biology and evolution [Mol Biol Evol] 2021 Jan 04; Vol. 38 (1), pp. 31-47.