Evolution of aberrant brain‐wide spatiotemporal dynamics of resting‐state networks in a Huntington's disease mouse model.

Autor: Vasilkovska, Tamara^1,2 (AUTHOR) tamara.vasilkovska@ucsf.edu, Verschuuren, Marlies^2,3,4 (AUTHOR), Pustina, Dorian⁵ (AUTHOR), van den Berg, Monica^1,2 (AUTHOR), Van Audekerke, Johan^1,2 (AUTHOR), Pintelon, Isabel^2,3,4 (AUTHOR), Cachope, Roger⁵ (AUTHOR), De Vos, Winnok H.^2,3,4 (AUTHOR), Van der Linden, Annemie^1,2 (AUTHOR), Adhikari, Mohit H.^1,2 (AUTHOR) mohit.adhikari@uantwerpen.be, Verhoye, Marleen^1,2 (AUTHOR)

Publikováno v: Clinical & Translational Medicine. Oct2024, Vol. 14 Issue 10, p1-24. 24p.

Frequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell-type-specific.

Autor: Jansen AH; Department of Cell biology & Histology, Academic Medical Center, Amsterdam, The Netherlands., van Hal M; Department of Cell biology & Histology, Academic Medical Center, Amsterdam, The Netherlands., Op den Kelder IC; Department of Cell biology & Histology, Academic Medical Center, Amsterdam, The Netherlands., Meier RT; Department of Cell biology & Histology, Academic Medical Center, Amsterdam, The Netherlands., de Ruiter AA; Department of Cell biology & Histology, Academic Medical Center, Amsterdam, The Netherlands., Schut MH; Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands., Smith DL; Department of Medical and Molecular Genetics, King's College London, London, United Kingdom., Grit C; Department of Neuroscience, Section Medical Physiology, University of Groningen, University Medical Center Groningen, Groningen, AV, 9713, The Netherlands., Brouwer N; Department of Neuroscience, Section Medical Physiology, University of Groningen, University Medical Center Groningen, Groningen, AV, 9713, The Netherlands., Kamphuis W; Netherlands Institute for Neuroscience, an institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands., Boddeke HW; Department of Neuroscience, Section Medical Physiology, University of Groningen, University Medical Center Groningen, Groningen, AV, 9713, The Netherlands., den Dunnen WF; Department of Neuroscience, Section Medical Physiology, University of Groningen, University Medical Center Groningen, Groningen, AV, 9713, The Netherlands., van Roon WM; Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands., Bates GP; Department of Medical and Molecular Genetics, King's College London, London, United Kingdom., Hol EM; Netherlands Institute for Neuroscience, an institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, The Netherlands.; Swammerdam Institute for Life Sciences, Center for Neuroscience, University of Amsterdam, The Netherlands., Reits EA; Department of Cell biology & Histology, Academic Medical Center, Amsterdam, The Netherlands.

Publikováno v: Glia [Glia] 2017 Jan; Vol. 65 (1), pp. 50-61. Date of Electronic Publication: 2016 Sep 12.

The phase coherence of the neurovascular unit is reduced in Huntington's disease.

Autor: Bjerkan, Juliane, Kobal, Jan, Lancaster, Gemma, Šešok, Sanja, Meglič, Bernard, McClintock, Peter V E, Budohoski, Karol P, Kirkpatrick, Peter J, Stefanovska, Aneta

Publikováno v: Brain Communications; 2024, Vol. 6 Issue 3, p1-17, 17p

Microglial physiological properties and interactions with synapses are altered at presymptomatic stages in a mouse model of Huntington's disease pathology.

Autor: Savage, Julie C.¹ (AUTHOR) julie.savage@gmail.com, St-Pierre, Marie-Kim¹ (AUTHOR), Carrier, Micaël¹ (AUTHOR), El Hajj, Hassan¹ (AUTHOR), Novak, Sammy Weiser^1,2 (AUTHOR), Sanchez, Maria Gabriela¹ (AUTHOR), Cicchetti, Francesca^1,3 (AUTHOR), Tremblay, Marie-Ève^1,4,5 (AUTHOR) tremblay0202@gmail.com

Publikováno v: Journal of Neuroinflammation. 4/2/2020, Vol. 17 Issue 1, p1-18. 18p.

Meso scale discovery-based assays for the detection of aggregated huntingtin.

Autor: Reindl, Wolfgang¹, Baldo, Barbara¹, Schulz, Jana¹, Janack, Isabell¹, Lindner, Ilka¹, Kleinschmidt, Markus¹, Sedaghat, Yalda¹, Thiede, Christina¹, Tillack, Karsten¹, Schmidt, Christina¹, Cardaun, Isabell¹, Schwagarus, Tom¹, Herrmann, Frank¹, Hotze, Madlen¹, Osborne, Georgina F.², Herrmann, Simone¹, Weiss, Andreas¹, Zerbinatti, Celina¹, Bates, Gillian P.², Bard, Jonathan³

Publikováno v: PLoS ONE. 3/26/2019, Vol. 14 Issue 3, p1-25. 25p.