Determinants of successful immune tolerance induction in hemophilia A: systematic review and meta-analysis

Autor: Oomen, Ilja, Camelo, Ricardo M., Rezende, Suely Meireles, Voorberg, Jan, Mancuso, Maria Elisa, Oldenburg, Johannes, Carcao, Manuel, Matino, Davide, Lillicrap, David, Fischer, Kathelijn, Fijnvandraat, Karin, Gouw, Samantha C.

Publikováno v: In Research and Practice in Thrombosis and Haemostasis January 2023 7(1)

Anti-rituximab antibodies affect pharmacokinetics and pharmacodynamics of rituximab in children with immune-mediated diseases

Autor: Oomen, Ilja, Rashid, Amara Nassar-Sheikh, Bouts, Antonia H. M., Gouw, Samantha C., Kuijpers, Taco W., Rispens, Theo, de Vries, Annick, Wolbink, Gertjan, van den Berg, J. Merlijn, Schonenberg-Meinema, Dieneke

Publikováno v: Clinical and experimental rheumatology, 39(5), 183-190. Clinical and Experimental Rheumatology S.A.S.
Clinical and Experimental Rheumatology, 40(1), 183-190. Clinical and Experimental Rheumatology S.A.S.
Clinical and Experimental Rheumatology, 39(5), 183-190. Clinical and Experimental Rheumatology S.A.S.
Oomen, I, Rashid, A N-S, Bouts, A H M, Gouw, S C, Kuijpers, T W, Rispens, T, de Vries, A, Wolbink, G, van den Berg, J M & Schonenberg-Meinema, D 2021, ' Anti-rituximab antibodies affect pharmacokinetics and pharmacodynamics of rituximab in children with immune-mediated diseases ', Clinical and Experimental Rheumatology, vol. 39, no. 5, pp. 183-190 . https://doi.org/10.55563/CLINEXPRHEUMATOL/FTIRA8

Objective Rituximab (RTX) is a chimeric monoclonal CD20-antibody. Lack of efficacy has been suggested to be related to the presence of anti-drug antibodies (ADA). The aims of this study were to determine if ADA impact the pharmacokinetics (PK) and ph

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Determinants of successful immune tolerance induction in hemophilia A: systematic review and meta-analysis.

Autor: Oomen I; Amsterdam University Medical Center location University of Amsterdam, Department of Pediatric Hematology, Meibergdreef 9, Amsterdam, The Netherlands.; Department of Molecular Hematology, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands., Camelo RM; Department of Internal Medicine, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Rezende SM; Department of Internal Medicine, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Voorberg J; Department of Molecular Hematology, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands., Mancuso ME; Center for Thrombosis and Hemorrhagic Diseases, Instituto di Ricovero e Cura a Carattere Scientifico Humanitas Research Hospital, Rozzano, Milan, Italy., Oldenburg J; Department of Internal Medicine, University Clinic Bonn, University of Bonn, Bonn, Germany., Carcao M; Division of Hematology/Oncology, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, Canada., Matino D; Department of Medicine, McMaster University, University of Hamilton, Hamilton, Canada., Lillicrap D; Department of Pathology and Molecular Medicine, Queen's University, Kingston, Canada., Fischer K; Department of Hematology, Van Creveldkliniek, University Medical Center Utrecht, Utrecht, The Netherlands., Fijnvandraat K; Amsterdam University Medical Center location University of Amsterdam, Department of Pediatric Hematology, Meibergdreef 9, Amsterdam, The Netherlands.; Department of Molecular Hematology, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands., Gouw SC; Amsterdam University Medical Center location University of Amsterdam, Department of Pediatric Hematology, Meibergdreef 9, Amsterdam, The Netherlands.; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

Publikováno v: Research and practice in thrombosis and haemostasis [Res Pract Thromb Haemost] 2022 Dec 20; Vol. 7 (1), pp. 100020. Date of Electronic Publication: 2022 Dec 20 (Print Publication: 2023).