Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Ook Joon Yoo"'
Autor:
Kyoo Hyun Kim, Jeon Yeob Jang, Young Jun Koh, Junyeop Lee, Daesoo Kim, Seung Hun Lee, Gou Young Koh, Ook Joon Yoo
Publikováno v:
Blood. 122:2151-2161
To unveil the organotypic role and vulnerability of lymphatic vessels, we generated a lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1)-Cre/iDTR double-transgenic mouse and ablated LYVE-1-expressing lymphatic vessels in adult mice in a diph
Autor:
Sungha Park, Yoon Seok Choi, Yangsoo Jang, Jong Chan Youn, Dong Yeop Chang, Sang Hak Lee, Hee Tae Yu, Jino Lee, Seok Min Kang, Myoung Ju Koh, Ook Joon Yoo, Eui-Cheol Shin, Beom Jin Lim
Publikováno v:
Hypertension. 62:126-133
The pathogenic role of T cells in hypertension has been documented well in recent animal studies. However, the existence of T-cell–driven inflammation in human hypertension has not been confirmed. Therefore, we undertook immunologic characterizatio
Autor:
Guang-Ho Cha, Young-Ha Lee, Kyu-Sun Lee, Sang-Gi Paik, Jongkyeong Chung, Ook-Joon Yoo, Wonseok Son, Oky Maeng
Publikováno v:
Molecules and Cells. 33:457-463
In Drosophila, broad complex, tramtrack, bric à brac (BTB)/ poxvirus and zinc finger (POZ) transcription factors are essential regulators of development. We searched the Drosophila genome for BTB/POZ-ZF domains and discovered an unknown Drosophila g
Autor:
Nam Kyu Lim, Jeung Eun Lee, Hoon Ki Sung, Gou Young Koh, Byeong Hwa Jeon, Kyung Eun Kim, Ho Min Kim, Minah Kim, Young Jun Koh, Seong Ik Hwang, Do-Hyun Nam, Keehoon Jung, Ook Joon Yoo, Choon Ju Jeon, Nuri Oh, Hak Zoo Kim, Andras Nagy, Gyun Min Lee
Publikováno v:
Cancer Cell. 18(2):171-184
SummaryTwo vascular growth factor families, VEGF and the angiopoietins, play critical and coordinate roles in tumor progression and metastasis. A single inhibitor targeting both VEGF and angiopoietins is not available. Here, we developed a chimeric d
Publikováno v:
Life Sciences. 86:66-72
Aims The phosphatase of regenerating liver (PRL) family is related to tumorigenesis and metastasis in various cancer types. Its overexpression increases cell motility and proliferation via the downregulation of p21 expression. In a previous study, we
Autor:
Ook Joon Yoo, Soon-Chun Jeong, Suk Weon Kim, Suk Min Ko, Hwa-Jee Chung, Jang R. Liu, Sung Hee Ban
Publikováno v:
Biotechnology and Bioprocess Engineering. 12:646-652
When whole cell extracts are subjected to proton nuclear magnetic resonance spectroscopy (1H NMR), metabolite profiles are generated that contain overlapping signals of the majority of compounds within the extract. In order to determine whether patte
Autor:
Beom Seok Park, Norio Matsushima, Sung-Eun Kim, Judong Lee, Ook Joon Yoo, Jie-Oh Lee, SeCheol Oh, Ho Min Kim, Hayyoung Lee, Purevjav Enkhbayar, Jung-In Kim
Publikováno v:
Cell. 130(5):906-917
SummaryTLR4 and MD-2 form a heterodimer that recognizes LPS (lipopolysaccharide) from Gram-negative bacteria. Eritoran is an analog of LPS that antagonizes its activity by binding to the TLR4-MD-2 complex. We determined the structure of the full-leng
Publikováno v:
Plant Biotechnology Reports. 1:61-65
Pyrolysis mass spectrometry (PyMS) is a rapid, simple, high-resolution analytical method based on thermal degradation of complex material in a vacuum, and has been widely applied to the discrimination of closely related microbial strains. Minimally p
Autor:
Hosung Bae, Ralf H. Adams, Intae Park, Ook Joon Yoo, Hail Kim, Kyun Hoo Kim, Daeyoung Park, Ki Yong Hong, Yoshiaki Kubota, Gou Young Koh, Eui Sic Cho
Publikováno v:
Development (Cambridge, England). 142(15)
Despite the growing interest in adipose tissue as a therapeutic target of metabolic diseases, the identity of adipocyte precursor cells (preadipocytes) and the formation of adipose tissue during embryonic development are still poorly understood. Here
Autor:
Gou Young Koh, Goo Taeg Oh, Kyung Tae Kim, Chung-Hyun Cho, Ook Joon Yoo, Hyae Gyeong Cheon, Hoon Ki Sung, Hyo Jeong Hong
Publikováno v:
Proceedings of the National Academy of Sciences. 103:4946-4951
Microvascular dysfunction is a major cause of impaired wound healing seen in diabetic patients. Therefore, reestablishment of structural and functional microvasculature could be beneficial to promote wound healing in these patients. Angiopoietin-1 (A