Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Onur Cizmecioglu"'
Publikováno v:
eLife, Vol 5 (2016)
We aimed to understand how spatial compartmentalization in the plasma membrane might contribute to the functions of the ubiquitous class IA phosphoinositide 3-kinase (PI3K) isoforms, p110α and p110β. We found that p110β localizes to membrane rafts
Externí odkaz:
https://doaj.org/article/26ce0d83ad30440eb3451f71eeb047fd
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e14711 (2011)
Entry into and progression through mitosis depends on phosphorylation and dephosphorylation of key substrates. In yeast, the nucleolar phosphatase Cdc14 is pivotal for exit from mitosis counteracting Cdk1-dependent phosphorylations. Whether hCdc14B,
Externí odkaz:
https://doaj.org/article/d49ac31b64f44c429650cd8981f7dbb5
Autor:
Thomas M. Roberts, Jean J. Zhao, Massimo Loda, Guo-Cheng Yuan, Sabina Signoretti, Isha Sethi, Yi Yang, Raymond Pagliarini, Lan Jiang, Fabienne Schmit, Zhigang Wang, Joshua M. Korn, Manav Korpal, Shidong Jia, Onur Cizmecioglu, Silvia Rodrigues, Thanh Von, Hyeyoun Chang, Cherubin Manokaran, Caroline F. Ribeiro, Yubao Wang, Xueliang Gao
Supplementary Table from Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20cef1f671739e29898e6794e46088ad
https://doi.org/10.1158/1541-7786.22527902
https://doi.org/10.1158/1541-7786.22527902
Autor:
Thomas M. Roberts, Jean J. Zhao, Massimo Loda, Guo-Cheng Yuan, Sabina Signoretti, Isha Sethi, Yi Yang, Raymond Pagliarini, Lan Jiang, Fabienne Schmit, Zhigang Wang, Joshua M. Korn, Manav Korpal, Shidong Jia, Onur Cizmecioglu, Silvia Rodrigues, Thanh Von, Hyeyoun Chang, Cherubin Manokaran, Caroline F. Ribeiro, Yubao Wang, Xueliang Gao
Supplementary Data from Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63af032d9cbd4d431caa25fcdc1d3af0
https://doi.org/10.1158/1541-7786.22527914.v1
https://doi.org/10.1158/1541-7786.22527914.v1
Autor:
Thomas M. Roberts, Jean J. Zhao, Massimo Loda, Guo-Cheng Yuan, Sabina Signoretti, Isha Sethi, Yi Yang, Raymond Pagliarini, Lan Jiang, Fabienne Schmit, Zhigang Wang, Joshua M. Korn, Manav Korpal, Shidong Jia, Onur Cizmecioglu, Silvia Rodrigues, Thanh Von, Hyeyoun Chang, Cherubin Manokaran, Caroline F. Ribeiro, Yubao Wang, Xueliang Gao
Supplementary Figure from Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ee2c6ec730da34e869cffe1113668e
https://doi.org/10.1158/1541-7786.22527908
https://doi.org/10.1158/1541-7786.22527908
Autor:
Xueliang Gao, Yubao Wang, Caroline F. Ribeiro, Cherubin Manokaran, Hyeyoun Chang, Thanh Von, Silvia Rodrigues, Onur Cizmecioglu, Shidong Jia, Manav Korpal, Joshua M. Korn, Zhigang Wang, Fabienne Schmit, Lan Jiang, Raymond Pagliarini, Yi Yang, Isha Sethi, Sabina Signoretti, Guo-Cheng Yuan, Massimo Loda, Jean J. Zhao, Thomas M. Roberts
Publikováno v:
Molecular Cancer Research
Mol Cancer Res
Mol Cancer Res
A common outcome of androgen deprivation in prostate cancer therapy is disease relapse and progression to castration-resistant prostate cancer (CRPC) via multiple mechanisms. To gain insight into the recent clinical findings that highlighted genomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417496ddabb9a0b6f08cefe8db0057fc
https://hdl.handle.net/11693/111708
https://hdl.handle.net/11693/111708
Autor:
Claude Antony, Ramona Bahtz, Florian Settele, Marc Arnold, Onur Cizmecioglu, Ingrid Hoffmann, Lena Ehret, Uta Haselmann-Weiß
Publikováno v:
The Journal of Cell Biology
Cep152 interacts with the cryptic Polo-box of Plk4 and is required for Plk4-induced centriole overduplication.
Both gain and loss of function studies have identified the Polo-like kinase Plk4/Sak as a crucial regulator of centriole biogenesis, b
Both gain and loss of function studies have identified the Polo-like kinase Plk4/Sak as a crucial regulator of centriole biogenesis, b
Publikováno v:
The EMBO Journal. 29:2395-2406
Control of centrosome duplication is tightly linked with the progression of the cell cycle. Recent studies suggest that the fundamental process of centriole duplication is evolutionally conserved. Here, we identified centrosomal P4.1-associated prote