An altered extracellular matrix-integrin interface contributes to Huntington's disease-associated CNS dysfunction in glial and vascular cells

Autor: Hernandez, Sarah J, Lim, Ryan G, Onur, Tarik, Dane, Mark A, Smith, Rebecca, Wang, Keona, Jean, Grace En-Hway, Reyes-Ortiz, Andrea, Devlin, Kaylyn, Miramontes, Ricardo, Wu, Jie, Casale, Malcolm, Kilburn, David, Heiser, Laura M, Korkola, James E, Van Vactor, David, Botas, Juan, Thompson-Peer, Katherine L, Thompson, Leslie M

Publikováno v: Human molecular genetics, vol 32, iss 9

Astrocytes and brain endothelial cells are components of the neurovascular unit that comprises the blood-brain barrier (BBB) and their dysfunction contributes to pathogenesis in Huntington's disease (HD). Defining the contribution of these cells to d

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https://escholarship.org/uc/item/15t7q8h1

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Reduction of Environmental Temperature Mitigates Local Anesthetic Cytotoxicity in Bovine Articular Chondrocytes.

Autor: Onur, Tarik¹ t.s.onur17@gmail.com, Dang, Alexis¹ alexis.dang@gmail.com

Publikováno v: Journal of Sports Science & Medicine. Sep2014, Vol. 13 Issue 3, p516-521. 6p.

Joint instability and cartilage compression in a mouse model of posttraumatic osteoarthritis

Autor: Onur, Tarik S, Wu, Ruobin, Chu, Stacey, Chang, Wenhan, Kim, Hubert T, Dang, Alexis BC

Publikováno v: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, vol 32, iss 2

Joint instability and cartilage trauma have been previously studied and identified as key mediators in the development of posttraumatic osteoarthritis (PTOA). The purpose of this study was to use an in vivo model to compare the effect of joint instab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::1b93793c4aed98939450a78af1562e8b
https://escholarship.org/uc/item/2dt1r4wv

An altered extracellular matrix-integrin interface contributes to Huntington's disease-associated CNS dysfunction in glial and vascular cells.

Autor: Hernandez SJ; Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA 92697, USA., Lim RG; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA 92697, USA., Onur T; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX, USA.; Genetics & Genomics Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA., Dane MA; Department of Biomedical Engineering, OHSU, Portland, OR 97239, USA., Smith R; Department of Biomedical Engineering, OHSU, Portland, OR 97239, USA., Wang K; Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA 92697, USA., Jean GE; Department of Developmental and Cell Biology, University of California, Irvine, CA 92697, USA., Reyes-Ortiz A; Department of Biological Chemistry, University of California Irvine, Irvine, CA 92697, USA., Devlin K; Department of Biomedical Engineering, OHSU, Portland, OR 97239, USA., Miramontes R; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA 92697, USA., Wu J; Department of Biological Chemistry, University of California Irvine, Irvine, CA 92697, USA., Casale M; Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA 92697, USA., Kilburn D; Department of Biomedical Engineering, OHSU, Portland, OR 97239, USA., Heiser LM; Department of Biomedical Engineering, OHSU, Portland, OR 97239, USA.; OHSU Knight Cancer Institute, Portland, OR 97239, USA., Korkola JE; Department of Biomedical Engineering, OHSU, Portland, OR 97239, USA.; OHSU Knight Cancer Institute, Portland, OR 97239, USA., Van Vactor D; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA., Botas J; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX, USA.; Genetics & Genomics Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA.; Quantitative & Computational Biosciences, Baylor College of Medicine, Houston, TX 77030, USA., Thompson-Peer KL; Department of Developmental and Cell Biology, University of California, Irvine, CA 92697, USA.; Reeve-Irvine Research Center, University of California, Irvine, CA 92697, USA.; Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697, USA.; Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine, CA 92697, USA., Thompson LM; Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA 92697, USA.; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA 92697, USA.; Department of Biological Chemistry, University of California Irvine, Irvine, CA 92697, USA.; Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697, USA.; Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine, CA 92697, USA.; Department of Psychiatry and Human Behavior, University of California Irvine, Irvine, CA 92697, USA.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2023 Apr 20; Vol. 32 (9), pp. 1483-1496.