Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Onno J. de Boer"'
Autor:
Kartika R. Pertiwi, Marcel B. M. Teunissen, Gabrielle Krebbers, Martine C.M. Willems, Laurens Huisman, Cindy Poelen, Allard C. van der Wal, Onno J. de Boer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionInnate lymphoid cells (ILCs) have been implicated in multiple pathologic conditions, including atherogenesis, as documented in experimental mice studies, however, their role in atherosclerosis in humans remains unexplored.MethodsHere, we
Externí odkaz:
https://doaj.org/article/4d9ca244153d4cf8b8cbf3794bc01946
Autor:
Amalia Mulia Utami, MD, Max M. Lokhorst, MD, PhD, Lorine B. Meijer-Jorna, MD, PhD, Mara A. Kruijt, BSc, Sophie E.R. Horbach, MD, PhD, Onno J. de Boer, PhD, Chantal M.A.M. van der Horst, MD, PhD, Allard C. van der Wal, MD, PhD
Publikováno v:
JAAD International, Vol 12, Iss , Pp 15-23 (2023)
Background: Discrepancies have been noted between the clinical and histologic diagnosis of vascular malformations. Objective: To evaluate the effectiveness of the International Society for Study of Vascular Anomalies (ISSVA) classification in diagnos
Externí odkaz:
https://doaj.org/article/17fd42cd614745aaaca8f81f6493a294
Autor:
Eva R. Meulendijks, Rushd F. M. Al-Shama, Makiri Kawasaki, Benedetta Fabrizi, Jolien Neefs, Robin Wesselink, Auriane C. Ernault, Sander Piersma, Thang V. Pham, Connie R. Jimenez, Jaco C. Knol, Wim J. P. van Boven, Antoine H. G. Driessen, Tim A. C. de Vries, Britt van der Leeden, Hans W. M. Niessen, Onno J. de Boer, Sébastien P. J. Krul, Joris R. de Groot
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Epicardial adipose tissue (EAT) secretome induces fibrosis. Fibrosis, primarily extracellular matrix (ECM) produced by fibroblasts, creates a substrate for atrial fibrillation (AF). Whether the EAT secretome from patients with AF
Externí odkaz:
https://doaj.org/article/b6cf7114ad5148eaab99d938a3be13c0
Autor:
Bart Van Gorsel, Michel J.M. Remmers, Louwerens D. Vos, Bas E. Scholzel, Dirk A.W. Haans, Ruud A.H.M. Aarts, Rob J. Versteylen, Anouk G.W. Van Norden, Casper A.M.M. Van Oers, Jeroen Vos, Sander J.J. IJsselmuiden, Ben J.L. Van Den Branden, Onno J. De Boer, Farshad Imani, Marco Alings, Kartika R. Pertiwi, Robbert J. De Winter, Ishita Miah, Allard C. Van Der Wal, Tim P. Van De Hoef, Martijn Meuwissen
Publikováno v:
Cerebrovascular Diseases Extra, Pp 1-1 (2023)
Introduction Acute mechanical thrombectomy is the preferred treatment for large vessel occlusion related stroke. Histopathological research on the obtained occlusive embolic thrombus may provide information regarding the etiology and pathology of the
Externí odkaz:
https://doaj.org/article/9ca4d7a5d25247c0be2e3c242b3c1442
Autor:
Zhe Liu, Alexander P.N.A. De Porto, Regina De Beer, Joris J.T.H. Roelofs, Onno J. De Boer, Sandrine Florquin, Cornelis Van’t Veer, Rudi W. Hendriks, Tom Van der Poll, Alex F. De Vos
Publikováno v:
Journal of Innate Immunity, Pp 1-15 (2022)
Humans with dysfunctional Bruton’s tyrosine kinase (Btk) are highly susceptible to bacterial infections. Compelling evidence indicates that Btk is essential for B cell-mediated immunity, whereas its role in myeloid cell-mediated immunity against in
Externí odkaz:
https://doaj.org/article/9a182f02185d4c06a7e0960e061482bc
Autor:
Nicoline W. E. van den Berg, Makiri Kawasaki, Benedetta Fabrizi, Fransisca A. Nariswari, Arianne C. Verduijn, Jolien Neefs, Robin Wesselink, Rushd F. M. Al‐Shama, Allard C. van der Wal, Onno J. de Boer, Jan Aten, Antoine H. G. Driessen, Aldo Jongejan, Joris R. de Groot
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 11, Pp n/a-n/a (2021)
Abstract Background Improved understanding of the interconnectedness of structural remodeling processes in atrial fibrillation (AF) in patients could identify targets for future therapies. Methods We present transcriptome sequencing of atrial tissues
Externí odkaz:
https://doaj.org/article/1856597343d24eb6845f5da16fe68c38
Autor:
Alexander P. de Porto, Zhe Liu, Regina de Beer, Sandrine Florquin, Joris J. T. H. Roelofs, Onno J. de Boer, Joke M. M. den Haan, Rudi W. Hendriks, Cornelis van ‘t Veer, Tom van der Poll, Alex F. de Vos
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Bruton’s tyrosine kinase (Btk) is a cytoplasmic kinase expressed in B cells and myeloid cells. It is essential for B cell development and natural antibody-mediated host defense against bacteria in humans and mice, but little is known about the role
Externí odkaz:
https://doaj.org/article/6534ee5b3c2444c6b14ce70febc59ba2
Autor:
Ilaria Jansen, Marit Lucas, C. Dilara Savci-Heijink, Sybren L. Meijer, Esmee I. M. L. Liem, Onno J. de Boer, Ton G. van Leeuwen, Henk A. Marquering, Daniel M. de Bruin
Publikováno v:
Diagnostic Pathology, Vol 14, Iss 1, Pp 1-7 (2019)
Abstract Background Histopathological analysis is the cornerstone in bladder cancer (BCa) diagnosis. These analysis suffer from a moderate observer agreement in the staging of bladder cancer. Three-dimensional reconstructions have the potential to su
Externí odkaz:
https://doaj.org/article/313e839a28934f3891bfcc53c28904fb
Autor:
Alexander P. de Porto, Zhe Liu, Regina de Beer, Sandrine Florquin, Onno J. de Boer, Rudi W. Hendriks, Tom van der Poll, Alex F. de Vos
Publikováno v:
Molecular Medicine, Vol 25, Iss 1, Pp 1-10 (2019)
Abstract Background Streptococcus pneumoniae is a major causative agent in community-acquired pneumonia and sepsis. Overwhelming lung inflammation during pneumococcal pneumonia may hamper lung function. Ibrutinib is an irreversible inhibitor of Bruto
Externí odkaz:
https://doaj.org/article/7cc2f9884a124007aa14943727f594cd
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 26, Iss , Pp - (2020)
Background: Coronary thrombosis is a process with unpredictable clinical outcome. Changes of thrombus composition overtime influence tissue repair and stabilization. We investigated rates of cell deaths and cell proliferation at different time points
Externí odkaz:
https://doaj.org/article/b2fa816e92ba4778b421c4fd2aae0a34